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Mouse models that recapitulate many aspects of the genesis, progression, and clinical course of human cancers are valuable resources to cancer researchers engaged in a variety of basic, translational, clinical, and epidemiological investigations. The NCI Mouse Models of Human Cancers Consortium (MMHCC) is a collaborative program designed to derive and characterize mouse models, and to generate resources, information, and innovative approaches to the application of mouse models in cancer research.
In addition to the MMHCC initiative, the NCI sponsors numerous other projects to develop, analyze, and apply mouse cancer models. This site is intended to provide the cancer research community with information about mouse models and mouse research generated by the MMHCC and other NCI-supported projects.
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Overviews of organ site models, mouse model publications, industrial partners,
and therapeutics
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Therapies resulting from clinical trials, and
comparisons between mouse and human cancers |
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Information about sources of mouse stocks, cancer genes, pathways, drugs, collections of mutants,
protocols and reagents, analytical tools, and funding opportunities
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Information regarding the MMHCC organization, organizational activities,
and meetings |
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Announcements, calendar of activities, newsletters, press releases, and the PI Listserv. Contact information for Principal Investigators, co-Principal Investigators and Collaborators.
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Tools for uploading and browsing mouse model related data
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Provides "how to" information for mouse model engineering, which includes tutorials about statistics and histology (comparison of mouse models and human disease, images, markers, and protocols).
Online books, journals, dictionary, cancer news, mouse strain nomenclature
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