U.S. Department of Health & Human Services National Institutes of Health Diseases and Conditions Index DCI Home NHLBI Home About This Site NHLBI Home NHLBI Home
U.S. Department of Health & Human Services * National Institutes of Health
National Heart, Lung, and Blood Institute:  Diseases and Conditions Index
Tell us what you think about this site
   Enter keywords to search this site. (Click here for Search Tips)  
DCI Home: Heart & Vascular Diseases: Coronary Artery Disease: What Is ...

      Coronary Artery Disease
 
What Is ...
Other Names
Causes
Who Is At Risk
Signs & Symptoms
Diagnosis
Prevention
Treatments
Summary
Links
 
What Is Coronary Artery Disease?

Coronary artery disease (CAD) occurs when the arteries that supply blood to the heart muscle (coronary arteries) become hardened and narrowed. The arteries harden and become narrow due to the buildup of plaque on the inner walls or lining of the arteries (atherosclerosis). Blood flow to the heart is reduced as plaque narrows the coronary arteries. This decreases the oxygen supply to the heart muscle.

CAD is the most common type of heart disease. It is the leading cause of death in the U.S. in both men and women.

When blood flow and oxygen supply to the heart are reduced or cut off, you can develop:
  • Angina. Angina is chest pain or discomfort that occurs when your heart is not getting enough blood.


  • Heart attack. A heart attack happens when a blood clot suddenly cuts off most or all blood supply to part of the heart. Cells in the heart muscle that do not receive enough oxygen-carrying blood begin to die. This can cause permanent damage to the heart muscle.
Over time, CAD can weaken your heart muscle and contribute to:
  • Heart failure. In heart failure, the heart is not able to pump blood to the rest of the body effectively. Heart failure does not mean that your heart has stopped or is about to stop working. But it does mean that your heart is failing to pump blood the way that it should.


  • Arrhythmias. Arrhythmias are changes in the normal rhythm of the heartbeats. Some can be quite serious.





NextOther Names


Email this Page Email all Sections Print all Sections Print all Sections of this Topic


Department of Health and Human Services National Institutes of Health National Heart, Lung, and Blood Institute
Blood Diseases | Heart and Blood Vessel Diseases | Lung Diseases | Sleep Disorders
NHLBI Privacy Statement | NHLBI Accessibility Policy
NIH Home | NHLBI Home | DCI Home | About DCI | Search
About NHLBI | Contact NHLBI

Note to users of screen readers and other assistive technologies: please report your problems here.