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Suboxone (Buprenorphine/Naloxone) Taper:
A Comparison of Two Schedules


For decades clinicians have been frustrated by the inability to successfully detoxify opiate addicted patients because opiate-based detoxification, one of the most effective means to achieving that goal, has been unavailable outside the very restrictive confines of narcotic treatment programs (NTPs). A new medication, Buprenorphine, shows promise as an effective aid for opiate detoxification. However, little data have been generated for the shorter-term use of Buprenorphine/Naloxone for this indication. This protocol will compare the clinical utility of two tapering dosage regimens in Buprenorphine/Naloxone stabilized subjects for opiate detoxification.

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The National Institute on Drug Abuse (NIDA) is part of the National Institutes of Health (NIH), a component of the U.S. Department of Health and Human Services. Questions? See our Contact Information. Last updated on Tuesday, February 17, 2004.