Defining and Managing Chronic Fatigue Syndrome: Clinical Focus

Musculoskeletal

Chronic Fatigue Syndrome

September 2001

Clinical Focus*

What are the existing case definitions of chronic fatigue syndrome (CFS) in adults?
Which case definitions, if any, have been substantiated and/or validated with reliably discriminating constellations of symptoms in adults?
What are the prevalence and natural history of CFS in adults?
Do controlled studies in adults show that particular therapies improve clinical symptoms of CFS when compared to placebo, no therapy, or each other?

*Addressed in the summary or evidence report.

Defining and Managing Chronic Fatigue Syndrome
Summary (Publication No. 01-E061, September 2001)
Evidence Report (Publication No. 02-E001, October 2001)
(File Download)

EPC: University of Texas HSC
Topic Nominator: National Institute of Allergy and Infectious Diseases

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