Evidence Report/Technology Assessment Number 26

Evaluation of Technologies for Identifying Acute Cardiac Ischemia in Emergency Departments

File Inventory


Prepared by:

New England Medical Center Evidence-based Practice Center
Joseph Lau, M.D.
   Principal Investigator
John P.A. Ioannidis, M.D.
Ethan Balk, M.D., M.P.H.
Catherine Milch, M.D.
Priscilla Chew, M.P.H.
Norma Terrin, Ph.D.
Thomas A. Lang, M.A.
Deeb Salem, M.D.
John B. Wong, M.D.
   Investigators


File Name		Description			Software	Version		File	Size
__________________________________________________________________________________________________________
01front.doc		Microsoft Word® Document	MS Word®	97 SR-1		38KB	6 pages
Contents: Inside Front Cover, Title Page, Preface, Structured Abstract

02cont.doc		Microsoft Word® Document	MS Word®	97 SR-1		26KB	3 pages
Contents: Table of Contents

03summ.doc		Microsoft Word® Document	MS Word®	97 SR-1		49KB	7 pages
Contents: Summary: Introduction; Reporting the Evidence; Methods; Findings; 
Results of Decision and Cost-Effectiveness Analysis; Future Research

04chap1.doc		Microsoft Word® Document	MS Word®	97 SR-1		121KB	11 pages
Contents: Chapter 1. Introduction: The 1997 NHAAP Report; The Charge To Update the 1997 Report; 
Issues in Diagnosing Acute Cardiac Ischemia in Emergency Departments; The Updated Evidence Report; 
Summary

05chap2.doc		Microsoft Word® Document	MS Word®	97 SR-1		86KB	12 pages
Contents: Chapter 2. Methods: Aim of the Evidence Report; Literature Search; Study Selection; 
Data Abstraction; Reporting the Results; Supplemental Analyses (Meta-Analysis, 
Decision and Cost-Effectiveness Analysis)

06chap3.doc		Microsoft Word® Document	MS Word®	97 SR-1		471KB	68 pages
Contents: Chapter 3. Results: Study Population Categories and Prevalence of AMI; 
Summary of Evidence for the Diagnostic Technologies

07chap4.doc		Microsoft Word® Document	MS Word®	97 SR-1		88KB	12 pages
Contents: Chapter 4. Conclusions: General Observations on the Studies Analyzed; 
Observations on the Prevalence of Acute Cardiac Ischemia; Conclusions About the 
Diagnostic Technologies; Decision and Cost-Effectiveness Analysis

08chap5.doc		Microsoft Word® Document	MS Word®	97 SR-1		30KB	3 pages
Contents: Chapter 5. Future Research: Diagnostic Performance Studies; 
Combinations of Diagnostic Technologies; Clinical Impact Studies; 
Multiple But Standardized Research Variables; Higher Quality Studies and Better Reporting

09refs.doc		Microsoft Word® Document	MS Word®	97 SR-1		72KB	9 pages
Contents: References

10etabls.doc		Microsoft Word® Document	MS Word®	97 SR-1		554KB	111 pages
Contents: Evidence Table 1a. Diagnostic performance studies evaluating prehospital 
12-lead electrocardiography for the diagnoses of acute cardiac ischemia; 
Evidence Table 1b. Clinical impact of randomized studies involving prehospital diagnoses 
to manage acute cardiac ischemia; 
Evidence Table 1c.  Clinical impact of nonrandomized studies involving prehospital diagnoses 
to manage acute cardiac ischemia; 
Evidence Table 2. Diagnostic performance studies evaluating continuous/serial electrocardiography 
for the diagnoses of acute cardiac ischemia in the emergency department; 
Evidence Table 3. Diagnostic performance evaluating nonstandard electrocardiography 
for the diagnoses of acute cardiac ischemia in the emergency department (all patients admitted); 
Evidence Table 4a. Diagnostic performance studies evaluating electrocardiographic exercise 
stress test for the diagnoses of acute cardiac ischemia in the emergency department; 
Evidence Table 4b. Clinical impact studies evaluating electrocardiographic exercise 
stress test to manage acute cardiac ischemia in the emergency department; 
Evidence Table 5a. Diagnostic performance studies evaluating presentation CK for AMI in the ED; 
Evidence Table 5b. Diagnostic performance studies evaluating presentation CK for AMI in the ED 
(other clinical studies); 
Evidence Table 6. Diagnostic performance studies evaluating serial CK for AMI in the ED; 
Evidence Table 7a. Diagnostic performance studies evaluating presentation CK-MB for AMI in the ED; 
Evidence Table 7b. Diagnostic performance studies evaluating presentation CK-MB for AMI in the ED 
(other clinical studies); 
Evidence Table 8a. Diagnostic performance studies evaluating serial CK-MB for AMI in the ED; 
Evidence Table 8b. Diagnostic performance studies evaluating serial CK-MB for AMI in the ED 
(other clinical trials); 
Evidence Table 9a. Diagnostic performance studies evaluating presentation troponin I 
for acute myocardial infarction in the emergency department; 
Evidence Table 9b. Diagnostic performance studies evaluating presentation troponin I 
for acute myocardial infarction in the emergency department (all patients admitted); 
Evidence Table 9c. Diagnostic performance studies evaluating serial troponin I 
for acute myocardial infarction in the emergency department; 
Evidence Table 9d. Diagnostic performance studies evaluating serial troponin I 
for acute myocardial infarction (patients admitted to CCU); 
Evidence Table 10a. Diagnostic performance studies evaluating presentation troponin T 
for acute myocardial infarction in the emergency department; 
Evidence Table 10b. Diagnostic performance studies evaluating presentation troponin T 
for acute myocardial infarction (other settings); 
Evidence Table 11a. Diagnostic performance studies evaluating serial troponin T 
for acute myocardial infarction in the emergency department; 
Evidence Table 11b. Diagnostic performance studies evaluating serial troponin T 
for acute myocardial infarction (other studies); 
Evidence Table 12. Diagnostic performance studies evaluating presentation myoglobin 
for AMI in the ED; 
Evidence Table 13a. Diagnostic performance studies evaluating serial myoglobin 
for AMI in the ED; 
Evidence Table 13b. Diagnostic performance studies evaluating serial myoglobin 
for AMI in the ED (other clinical trials); 
Evidence Table 14a. Diagnostic performance studies evaluating two-dimensional rest 
echocardiography for the diagnoses of acute cardiac ischemia in the emergency department; 
Evidence Table 14b. Diagnostic performance studies evaluating two-dimensional stress 
echocardiography for the diagnoses of acute cardiac ischemia in the emergency department; 
Evidence Table 15. Diagnostic performance studies evaluating technetium-99m sestamibi 
for the diagnoses of acute cardiac ischemia in the emergency department; 
Evidence Table 16a. Diagnostic performance studies evaluating ACI predictive instrument 
and ACI time-insensitive predictive instrument for the diagnoses of acute cardiac ischemia 
in the emergency department; 
Evidence Table 16b. Clinical impact studies evaluating ACI predictive instrument 
and ACI time-insensitive predictive instrument to manage acute cardiac ischemia 
in the emergency department; 
Evidence Table 17a. Diagnostic performance studies evaluating Goldman predictive instrument 
for the diagnoses of acute cardiac ischemia in the emergency department; 
Evidence Table 17b. Clinical impact studies evaluating Goldman predictive instrument 
to manage acute cardiac ischemia in the emergency department; 
Evidence Table 18a. Diagnostic performance studies evaluating algorithm protocols 
for the diagnoses of acute cardiac ischemia in the emergency department; 
Evidence Table 18b. Clinical impact studies evaluating algorithm protocols 
to manage acute cardiac ischemia in the emergency department; 
Evidence Table 19a. Diagnostic performance studies evaluating computer-based decision aids 
for the diagnoses of acute cardiac ischemia in the emergency department; 
Evidence Table 19b. Clinical impact studies evaluating computer-based decision aids 
to manage acute cardiac ischemia in the emergency department

11meta.doc		Microsoft Word® Document	MS Word®	97 SR-1		209KB	23 pages
Contents: Supplemental Analyses: Meta-Analyses

12deccst.doc		Microsoft Word® Document	MS Word®	97 SR-1		966KB	32 pages
Contents: Supplemental Analyses: Decision and Cost-Effectiveness Analysis

13biblio.doc		Microsoft Word® Document	MS Word®	97 SR-1		76KB	10 pages
Contents: Bibliography

14appa-1.doc		Microsoft Word® Document	MS Word®	97 SR-1		27KB	2 pages
Contents: Appendix A. Data Abstraction Forms: DIAGNOSTIC TESTS FOR ACI IN THE EMERGENCY DEPARTMENT 
INITIAL ARTICLE SCREEN FORM

15appa-2.doc		Microsoft Word® Document	MS Word®	97 SR-1		40KB	3 pages
Contents: Appendix A. Data Abstraction Forms: DIAGNOSTIC TESTS FOR ACI IN THE EMERGENCY DEPARTMENT

16appa-3.doc		Microsoft Word® Document	MS Word®	97 SR-1		30KB	2 pages
Contents: Appendix A. Data Abstraction Forms: Quality Assessment of Evaluations 
of Diagnostic Test Performance for ACI/AMI

17appb.doc		Microsoft Word® Document	MS Word®	97 SR-1		23KB	2 pages
Contents: Appendix B. Acknowledgments

18appc.doc		Microsoft Word® Document	MS Word®	97 SR-1		21KB	1 page
Contents: Appendix C. Acronyms
__________________________________________________________________________________________________________

AHRQ Publication No. 01-E006
Current as of May 2001


Internet Citation:

Evaluation of Technologies for Identifying Acute Cardiac Ischemia in Emergency Departments. File Inventory, Evidence Report/Technology Assessment Number 26. AHRQ Publication No. 01-E006, May 2001. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/clinic/aciscinv.htm


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