Prepared by:
RTI International-University of North Carolina Evidence-based Practice Center
Research Triangle Park, North Carolina
Investigators
Arthur J. Bonito, Ph.D.
Kathleen N. Lohr, Ph.D.
Linda Lux, M.P.A.
Sonya Sutton, B.S.P.H.
Anne Jackman, M.S.W.
Lynn Whitener, Dr.P.H.
Christian Evensen, M.S.
| File Name | Description | Software and Version | Size |
|---|---|---|---|
| 01title.doc | Title page | Word® 2002 | 73KB, 2 pages |
| 02pref.doc | Preface | Word® 2002 | 24KB, 2 pages |
| 03ackn.doc | Acknowledgments | Word® 2002 | 25KB, 1 page |
| 04abstr.doc | Structured Abstract | Word® 2002 | 71KB, 2 pages |
| 05conts.doc | Table of Contents | Word® 2002 | 81KB, 4 pages |
| 06summ.doc | Summary: Objectives, Methodology, Findings, Conclusions | Word® 2002 | 91KB, 5 pages |
| 07chap1.doc | Chapter 1. Introduction: Periodontal Disease and Periodontitis; Controlling Periodontal Infections; Origins of this Evidence Report; Organization of the Report; Table 1. Technical Expert Advisory Group for the Evidence Report on Effectiveness of Adjuncts to Scaling and Root Planing Therapy for Periodontitis; Figure 1. Diagrammatic Representation of Mechanical and/or Antimicrobial Therapy on Both the Microbial Load and Disease Risk | Word® 2002 | 131KB, 7 pages |
| 08chap2.doc | Chapter 2. Methods: Overview; Key Question and Causal Pathway; Literature Search and Analysis Strategy; Meta-Analysis; Quality Rating of Articles; Development of the Evidence Report; Figure 2. Added Effectiveness of Therapies Adjunctive to Scaling and Root Planing for Treatment of Chronic Periodontitis: Causal Pathway; Table 2. Strategy and Results of Original and Follow-up MEDLINE Searches; Table 3. Strategy and Results of EMBASE Search; Table 4. Inclusion/Exclusion Criteria For Studies of Added Effectiveness of Periodontitis Therapies Adjunctive to Scaling and Root Planing | Word® 2002 | 163KB, 12 pages |
| 09chap3.doc | Chapter 3. Results: Overview; Tetracycline; Minocycline; Metronidazole; Metronidazole with Amoxicillin; Chlorhexidine; Other Antibiotics; Local Antibiotics; Other Antimicrobials; Table 5. Main Features and Findings on Probing Depth and Clinical Attachment Level: Trials of Systemic Tetracycline; Table 6. Main Features and Findings on Probing Depth and Clinical Attachment Level: Trials of Local Tetracycline; Table 7. Main Features and Findings on Probing Depth and Clinical Attachment Level: Trials of Systemic Minocycline; Table 8. Main Features and Findings on Probing Depth and Clinical Attachment Level: Trials of Local Minocycline; Table 9. Main Features and Findings on Probing Depth and Clinical Attachment Level: Trials of Systemic Metronidazole; Table 10. Main Features and Findings on Probing Depth and Clinical Attachment Level: Trials of Local Metronidazole; Table 11. Main Features and Findings on Probing Depth and Clinical Attachment Level: Trials of Systemic Metronidazole plus Amoxicillin; Table 12. Main Features and Findings on Probing Depth and Clinical Attachment Level: Trials of Local Chlorhexidine; Table 13. Main Features and Findings on Probing Depth and Clinical Attachment Level: Trials of Other Systemic Antibiotics; Table 14. Main Features and Findings on Probing Depth and Clinical Attachment Level: Trials of Other Local Antibiotics; Table 15. Main Features and Findings on Probing Depth and Clinical Attachment Level: Trials of Other Antimicrobials; Figure 3. Meta-analysis of Systemic Tetracycline and SRP versus SRP Alone: Probing Depth; Figure 4. Meta-analysis of Local Tetracycline and SRP versus SRP Alone: Probing Depth; Figure 5. Meta-analysis of Local Tetracycline and SRP versus SRP Alone: Clinical Attachment Level; Figure 6. Meta-analysis of Local Minocycline and SRP versus SRP Alone: Probing Depth; Figure 7. Meta-analysis of Local Minocycline and SRP versus SRP Alone: Clinical Attachment Level; Figure 8. Meta-analysis of Local Metronidazole and SRP versus SRP Alone: Probing Depth; Figure 9. Meta-analysis of Local Metronidazole and SRP versus SRP Alone: Clinical Attachment Level; Figure 10. Meta-analysis of Local Chlorhexidine and SRP versus SRP Alone: Probing Depth; Figure 11. Meta-analysis of Local Chlorhexidine and SRP versus SRP Alone: Clinical Attachment Level | Word® 2002 | 848KB, 52 pages |
| 10chap4.doc | Chapter 4. Conclusions: Overview; Summary of Results; Concluding Comments; Table 16. Summary of Qualitative and Quantitative Results for Probing Depth and Clinical Attachment Level | Word® 2002 | 95KB, 8 pages |
| 11chap5.doc | Chapter 5. Recommendations for Future Research: Clinical Issues Concerning Antimicrobials; Improving Study Design and Conduct | Word® 2002 | 71KB, 6 pages |
| 12refs.doc | Chapter 6. References | Word® 2002 | 81KB, 8 pages |
| 13biblio.doc | Chapter 7. Full Bibliography | Word® 2002 | 241KB, 37 pages |
| 14appa.doc | Appendix A. Dental Abstraction Form | Word® 2002 | 186KB, 17 pages |
| 15appb.doc | Appendix B. Quality Review Checklist | Word® 2002 | 40KB, 4 pages |
| 16etcov.doc | Title page for Volume 2, Evidence Tables | Word® 2002 | 73KB, 2 pages |
| 17evtbls.doc | Evidence Tables: List of acronyms; Evidence Table 1a. Effectiveness of Systemic Tetracycline as an Adjunct to Scaling and Root Planing to Treat Chronic Periodontitis; Evidence Table 1b. Effectiveness of Local Tetracycline as an Adjunct to Scaling and Root Planing to Treat Chronic Periodontitis; Evidence Table 2a. Effectiveness of Systemic Minocycline as an Adjunct to Scaling and Root Planing to Treat Chronic Periodontitis; Evidence Table 2b. Effectiveness of Local Minocycline as an Adjunct to Scaling and Root Planing to Treat Chronic Periodontitis; Evidence Table 3a. Effectiveness of Systemic Metronidazole as an Adjunct to Scaling and Root Planing to Treat Chronic Periodontitis; Evidence Table 3b. Effectiveness of Local Metronidazole as an Adjunct to Scaling and Root Planing to Treat Chronic Periodontitis; Evidence Table 4. Effectiveness of Systemic Metronidazole and Amoxicillin as an Adjunct to Scaling and Root Planing to Treat Chronic Periodontitis; Evidence Table 5. Effectiveness of Local Chlorhexidine Combinations as an Adjunct to Scaling and Root Planing to Treat Chronic Periodontitis; Evidence Table 6a. Effectiveness of Other Systemic Antibiotics as an Adjunct to Scaling and Root Planing to Treat Chronic Periodontitis; Evidence Table 6b. Effectiveness of Other Local Antibiotics as an Adjunct to Scaling and Root Planing to Treat Chronic Periodontitis; Evidence Table 7. Effectiveness of Other Antimicrobials as an Adjunct to Scaling and Root Planing to Treat Chronic Periodontitis | Word® 2002 | 3.5MKB, 344 pages |
AHRQ Publication No. 04-E014-2
Current as of March 2004
Internet Citation:
Effectiveness of Antimicrobial Adjuncts to Scaling and Root Planing Therapy for Periodontitis. File Inventory, Evidence Report/Technology Assessment Number 88. AHRQ Publication No. 04-E014-2, March 2004. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/clinic/perioinv.htm
Return to Evidence-based Practice
Clinical Information
AHRQ Home Page
Department of Health and Human Services