Evidence Report/Technology Assessment Number 67

Management of Allergic Rhinitis in the Working-Age Population

File Inventory


Prepared by:

Duke Evidence-based Practice Center

Douglas C. McCrory, M.D., M.H.Sc.
John W. Williams, M.D.
Rowena J. Dolor, M.D., M.H.S.
Rebecca N. Gray, D.Phil.
Jane T. Kolimaga, M.A.
Shelby Reed, Ph.D.
John Sundy, M.D., Ph.D.
David L. Witsell, M.D.
   Investigators


File Name	Description			Software	Version	File	Size
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01front.doc	Microsoft Word® Document	MS Word®	2002	51KB	7 pages
Contents: Cover, Title Page, Preface, Structured Abstract
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02conts.doc	Microsoft Word® Document	MS Word®	2002	26KB	3 pages
Contents: Table of Contents
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03summ.doc	Microsoft Word® Document	MS Word®	2002	53KB	7 pages
Contents: Summary: Overview, Reporting the Evidence, Methodology, Findings, Future Research
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04chap1.doc	Microsoft Word® Document	MS Word®	2002	136KB	11 pages
Contents: Chapter 1. Introduction: Background, Scope and Purpose, Epidemiology of Allergic 
Rhinitis, Overview of Disease Biology, Burden of Illness, Management Strategies and Treatment 
Options, Costs and Work Performance, Treatment Outcomes by Clinician Specialty, Prevalence 
and Patient Outcomes by Race and Ethnicity, Target Populations, Target Practice Settings, 
Target Audience, Limitations of the Report; Table 1. 1996 US prevalence rates and numbers 
for hay fever/allergic rhinitis without asthma by age, sex, race, and family income; 
Table 2. 1996 US prevalence rates and numbers for hay fever/allergic rhinitis without asthma, 
by geographic location and place of residence
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05chap2.doc	Microsoft Word® Document	MS Word®	2002	267KB	23 pages
Contents: Chapter 2. Methodology: Topic Assessment and Refinement, Causal Pathway, Literature 
Search and Review, Data Abstraction, Grading of Articles (Quality Scoring), Quality Control 
Procedures; Figure 1. Causal Pathway; Table 3. Search strategy - preliminary general search, 
MEDLINE®, 1966 through September 2001; Table 4. Search strategy - clinician specialty differences, 
MEDLINE®, 1966 to October Week 3 2001; Table 5. Search strategy - environmental measures (1), 
MEDLINE®, 1966 to October Week 1 2001; Table 6. Search strategy - environmental measures (2), 
MEDLINE®, 1966 to October Week 1 2001; Table 7. Included study designs, by key research question; 
Table 8. Abstract and full-text screening criteria; Table 9. Summary of results of abstract and 
full-text screening; Table 10. Full-text screening results, by key research question and by 
inclusion/exclusion criteria; Table 11. Partial data abstraction - sample; Table 12. Oxford 
Centre for Evidence-based Medicine levels of evidence (May 2001)
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06chap3.doc	Microsoft Word® Document	MS Word®	2002	807KB	55 pages
Contents: Chapter 3. Results: Costs and Work Performance, Environmental Measures, Immunotherapy, 
Combined Treatments, Clinician Specialty Differences, Racial and Ethnic Variation; Figure 2. 
Meta-analysis of placebo-controlled trials of immunotherapy for seasonal allergic rhinitis; 
Figure 3. Meta-analysis of trials comparing antihistamine + decongestant combinations versus 
antihistamine alone: effect size based on differences in total symptom severity; Figure 4. 
Meta-analysis of trials comparing antihistamine + decongestant combinations versus antihistamine 
alone: effect size based on differences in nasal symptom severity; Figure 5. Meta-analysis of 
trials comparing antihistamine + decongestant combinations versus decongestant alone: effect 
size based on differences in total symptom severity; Figure 6. Meta-analysis of trials comparing 
antihistamine + decongestant combinations versus decongestant alone: effect size based on 
differences in nasal symptom severity; Figure 7. Meta-analysis of trials comparing antihistamine 
+ nasal glucocorticoid combinations versus antihistamine alone: effect size based on differences 
in nasal symptom severity; Figure 8. Meta-analysis of trials comparing antihistamine + nasal 
glucocorticoid combinations versus nasal glucocorticoid alone: effect size based on differences 
in nasal symptom severity; Table 13. Summary of types of data reported in studies abstracted 
in Evidence Table 1; Table 14. Placebo-controlled randomized controlled trials of injection 
immunotherapy (IT) for seasonal allergic rhinitis, by type of allergen; Table 15. Data abstracted 
for meta-analysis of placebo-controlled trials of immunotherapy (IT) for seasonal allergic 
rhinitis; Table 16. Placebo-controlled randomized controlled trials of injection immunotherapy 
(IT) for perennial allergic rhinitis, by type of allergen; Table 17. Randomized controlled trials 
comparing combination pharmacotherapy to monotherapy for allergic rhinitis; Table 18. Data 
abstracted for meta-analysis of combination treatment articles; Table 19. Summary of meta-analysis 
of randomized controlled trials comparing combination pharmacotherapy to monotherapy for allergic 
rhinitis
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07chap4.doc	Microsoft Word® Document	MS Word®	2002	32KB	3 pages
Contents: Chapter 4. Conclusions: Costs and Work Performance, Environmental Measures, Immunotherapy, 
Combined Treatments, Clinician Specialty Differences, Racial and Ethnic Variation
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08chap5.doc	Microsoft Word® Document	MS Word®	2002	31KB	3 pages
Contents: Chapter 5. Future Research: Costs and Work Performance, Environmental Measures, 
Immunotherapy, Combined Treatments, Clinician Specialty Differences, Racial and Ethnic Variation, 
Need for Improved and More Uniform Trial Reporting
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09refs.doc	Microsoft Word® Document	MS Word®	2002	81KB	9 pages
Contents: References
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10etbl1.doc	Microsoft Word® Document	MS Word®	2002	387KB	35 pages
Contents: Evidence Table 1. Costs and Work Performance
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11etbl2.doc	Microsoft Word® Document	MS Word®	2002	374KB	30 pages
Contents: Evidence Table 2. Environmental Measures
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12etbl3.doc	Microsoft Word® Document	MS Word®	2002	826KB	73 pages
Contents: Evidence Table 3. Immunotherapy
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13etbl4.doc	Microsoft Word® Document	MS Word®	2002	577KB	36 pages
Contents: Evidence Table 4. Combined Treatments
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14etbl5.doc	Microsoft Word® Document	MS Word®	2002	111KB	7 pages
Contents: Evidence Table 5. Provider Specialty
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15etbl6.doc	Microsoft Word® Document	MS Word®	2002	76KB	4 pages
Contents: Evidence Table 6. Racial and Ethnic Variation
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16biblio.doc	Microsoft Word® Document	MS Word®	2002	501KB	69 pages
Contents: Bibliography
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17acros.doc	Microsoft Word® Document	MS Word®	2002	21KB	2 pages
Contents: Appendix: Acronyms and Abbreviations
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AHRQ Publication No. 03-E015
Current as of March 2003


Internet Citation:

Management of Allergic Rhinitis in the Working-Age Population. File Inventory, Evidence Report/Technology Assessment Number 67. AHRQ Publication No. 03-E015, March 2003. Agency for Healthcare Research and Quality, Rockville, M.D.. http://www.ahrq.gov/clinic/rhnwkinv.htm


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