Evidence Report/Technology Assessment Number 73

Criteria for Determining Disability in Infants and Children: Short Stature

File Inventory


Prepared by:

Tufts-New England Medical Center EPC
Boston, MA

Investigators
   Patricia Wheeler, M.D.
   Karen Bresnahan, M.D.
   Barbara Shephard, M.D.
EPC Staff
   Joseph Lau, M.D., Director
   Ethan Balk, M.D., M.P.H., Project Leader
   Deirdre DeVine, M.Litt., Project Manager
   Mei Chung, M.P.H., Research Associate
   Kimberly Miller, B.A., Research Assistant


File Name	Description			Software	Version		File	Size
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01front.doc	Microsoft Word® Document	MS Word®	2002		112KB	12 pages
Contents: Title Page, Preface, Structured Abstract, Table of Contents
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02summ.doc	Microsoft Word® Document	MS Word®	2002		77KB	12 pages
Contents: Summary: Overview, Causes of Short Stature in Children, Reporting the Evidence, 
Methods, Findings, Limitations, Future Research
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03chap1.doc	Microsoft Word® Document	MS Word®	2002		41KB	4 pages
Contents: Chapter 1. Introduction: Scope of the Problem, Causes of Short Stature in Children
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04chap2.doc	Microsoft Word® Document	MS Word®	2002		50KB	6 pages
Contents: Chapter 2. Methodology: Key Questions Addressed by the Evidence Report 
(Question 1. Definition of Short Stature as a Result of Medically Determinable Impairment,
Question 2. Definition of Short Stature as a Result of Skeletal Dysplasia, Question 3. 
Chronic Disease and Linear Growth Velocity); Search Strategies; Study Selection; 
Data Abstraction; Summary Tables; Limitations
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05chap3.doc	Microsoft Word® Document	MS Word®	2002		1.0MB	58 pages
Contents: Chapter 3. Results: Search Results; Evidence Found Regarding Key Questions; 

Question 1. Is Short Stature as a Result of a Medically Determinable Impairment Associated 
With Severe Functional Limitations, According to, But Not Limited to, SSA's Definition of 
Disability?; Table 1. Mean Academic Achievement Scores of Children With Short Stature Due to 
Medical Impairment; Table 2. Mean Intelligence Quotients of Children With Short Stature 
Due to Medical Impairment; Table 3. Association of Height to Visual-Motor Skills Among Children 
With Short Stature Due to Medical Impairment; Table 4. Association of Height to Psychomotor 
Development Among Children With Short Stature Due to Medical Impairment; Table 5. Association 
of Height to Teacher-Graded Behavior Problems Among Children  With Short Stature Due to Medical 
Impairment;

Question 2. What is the Evidence That Short Stature Due to a Skeletal Dysplasia is Disabling 
According to, But Not Limited to, SAA's Definition of Disability? If So, Are Children Disabled 
by Virtue of Their Size or Other Features of Their Conditions?; Table 6. Academic Achievement 
Score of Children With Short Stature due to Skeletal Dysplasia; Table 7. Intelligence Quotient 
of Children With Short Stature Due to Skeletal Dysplasia; Table 8. Visual Motor Skills in Children 
With Short Stature Due to Skeletal Dysplasia; Table 9. Motor Development in Children With Short 
Stature Due to Skeletal Dysplasia; Table 10. Motor Development Patterns in Children With Short 
Stature Due to Skeletal Dysplasia; Table 11. Neuromuscular Findings in Chldren With Skeletal 
Dysplasia; Table 12. Ambulation/Mobility of Children With Short Stature Due to Skeletal Dysplasia; 
Table 13. Limb Range of Motion in Children With Skeletal Dysplasia; Table 14. Spinal Curvature 
in Children With Skeletal Dysplasia; Table 15. Heating Loss in Children With Short Stature 
Due to Skeletal Dysplasia; Table 16. Sleep Apnea in Children With Short Stature Due to Skeletal 
Dysplasia; Table 17. Pulmonary Function in Children With Short Stature Due to Skeletal Dysplasia; 
Table 18. Psychological Outcomes in Chldren With Skeletal Dysplasia;

Question 3. What is the Evidence That a Sustained Decrease in Linear Growth Velocity Can Be Used 
as a Marker of Severity of an Underlying Disease? Is Such a Process Likely To Be Disabling?; 
Table 19. Height Association With Severity of Asthma; Table 20. Growth Retardation Association With 
Severity of Congenital Heart Disease; Table 21. Growth Retardation Association With Control/Severity 
of Insulin Dependent Diabetes Mellitus; Table 22. Growth Retardation Association With Hemoglobin 
Level/Severity of ?-Thalassemia; Table 23. Growth Retardation Association With Severity of 
Inflammatory Bowel Disease; Table 24. Growth Retardation Association With Subtypes/Severity of 
Juvenile Rheumatoid Arthritis; Table 25. Growth Retardation Association With Severity of Chronic 
Kidney Disease; Table 26. Growth Retardation Association With Severity of Human Immunodeficiency 
Virus; Table 27. Growth Retardation Association With Severity of Atopic Dermatitis/Eczema
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06chap4.doc	Microsoft Word® Document	MS Word®	2002		58KB	10 pages
Contents: Chapter 4. Conclusions: Overview, Question 1, Question 2, Question 3, Limitations
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07chap5.doc	Microsoft Word® Document	MS Word®	2002		23KB	1 page
Contents: Chapter 5. Future Research: Questions 1 and 2, Question 3
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08refs.doc	Microsoft Word® Document	MS Word®	2002		67KB	6 pages
Contents: References and Bibliography
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09etbl1.doc	Microsoft Word® Document	MS Word®	2002		264KB	25 pages
Contents: Evidence Table 1. Studies Evaluating Short Stature Secondary to Medical Impairment
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10etbl2.doc	Microsoft Word® Document	MS Word®	2002		355KB	34 pages
Contents: Evidence Table 2. Studies Evaluating Short Stature Secondary to Skeletal Dysplasia
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11etbl3.doc	Microsoft Word® Document	MS Word®	2002		568KB	64 pages
Contents: Evidence Table 3. Association of Decreased Growth Velocity With Severity of Disease
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12appa.doc	Microsoft Word® Document	MS Word®	2002		94KB	2 pages
Contents: Appendix A. Main Search Performed in MEDLINE®
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13appb.doc	Microsoft Word® Document	MS Word®	2002		74KB	3 pages
Contents: Appendix B. Acronyms and Abbreviations
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14appc.doc	Microsoft Word® Document	MS Word®	2002		34KB	3 pages
Contents: Appendix C. Acknowledgements
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AHRQ Publication No. 03-E025
Current as of March 2003


Internet Citation:

Criteria for Determining Disability in Infants and Children: Short Stature. File Inventory, Evidence Report/Technology Assessment Number 73. AHRQ Publication No. 03-E025, March 2003. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/clinic/shortinv.htm


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