Prepared by:
Southern California Evidence-based Practice Center
George C. Velmahos, M.D., Ph.D., Principal Investigator
Jack Kern, Ph.D.
Linda Chan, Ph.D.
Danila Oder
James A. Murray, M.D.
Paul Shekelle, M.D.
File Name Description Software Version File Size _________________________________________________________________________________ 01title.doc Microsoft Word® Document MS Word® 97 SR-1 29KB 4 pages Contents: Cover Pages _________________________________________________________________________________ 02front.doc Microsoft Word® Document MS Word® 97 SR-1 48KB 7 pages Contents: Preface, Structured Abstract, Table of Contents _________________________________________________________________________________ 03summ.doc Microsoft Word® Document MS Word® 97 SR-1 41KB 6 pages Contents: Summary _________________________________________________________________________________ 04cover.doc Microsoft Word® Document MS Word® 97 SR-1 19KB 2 pages Contents: Cover Page for Body of Evidence Report _________________________________________________________________________________ 05chap1.doc Microsoft Word® Document MS Word® 97 SR-1 40KB 4 pages Contents: Chapter 1. Introduction: Purpose, Scope of Work, Background and Description of the Problem _________________________________________________________________________________ 06chap2.doc Microsoft Word® Document MS Word® 97 SR-1 364KB 36 pages Contents: Chapter 2. Methodology: Scope of Work, Design of Technical Experts Panel, Design of the Study, Process of Selecting Variables to Be Studied, Refining the Questions: Defining Causal Pathways for the Selected Questions, Literature Search, Design of the Database, Data Collection Forms, Synthesis of Existing Data _________________________________________________________________________________ 07chap3.doc Microsoft Word® Document MS Word® 97 SR-1 786KB 40 pages Contents: Chapter 3. Results: Incidence of Deep Venous Thrombosis and Pulmonary Embolism in Trauma Patients, Question 1: What Is the Best Method of Venous Thromboembolism Prophylaxis?, Question 2: What Groups of Patients Are at High Risk of Developing Venous Thromboembolism?, Question 3: What Is the Best Method of Screening for Venous Thromboembolism?, Question 4: What Is the Role of Vena Cava Filters in Preventing Pulmonary Embolism? _________________________________________________________________________________ 08chap4.doc Microsoft Word® Document MS Word® 97 SR-1 98KB 10 pages Contents: Chapter 4. Supplemental Analysis: Analysis of Complications of Methods of Venous Thromboembolism Prevention, Cost-Effectiveness Analysis _________________________________________________________________________________ 09chap5.doc Microsoft Word® Document MS Word® 97 SR-1 54KB 6 pages Contents: Chapter 5. Conclusions: What Is the Incidence of Deep Venous Thrombosis and Pulmonary Embolism?, What Is the Best Method of Preventing Venous Thromboembolism?, What Are the Risk Factors for Venous Thromboembolism?, What Is the Role of Vena Cava Filters in Preventing Pulmonary Embolism?, Cost-Effectiveness, Limitations _________________________________________________________________________________ 10chap6.doc Microsoft Word® Document MS Word® 97 SR-1 30KB 4 pages Contents: Chapter 6. Future Research: Methods of Screening, Selection of Appropriate Patients for Venous Thromboembolism Prophylaxis, The Role of Vena Cava Filters _________________________________________________________________________________ 11refs.doc Microsoft Word® Document MS Word® 97 SR-1 43KB 6 pages Contents: References _________________________________________________________________________________ 12cover.doc Microsoft Word® Document MS Word® 97 SR-1 20KB 2 pages Contents: Cover Page for Evidence Tables _________________________________________________________________________________ 13etbls.doc Microsoft Word® Document MS Word® 97 SR-1 145KB 38 pages Contents: Evidence Tables: Evidence Table 1. Description of 12 unused randomized controlled trials, Evidence Table 2. Four randomized controlled trials comparing low-dose heparin vs. no prophylaxis, Evidence Table 3. Three randomized controlled trials comparing mechanical prophylaxis vs. no prophylaxis, Evidence Table 4. Three studies comparing low-dose heparin vs. low-molecular-weight heparin, Evidence Table 5. Four studies comparing low-dose heparin vs. mechanical prophylaxis, Evidence Table 6. Five studies comparing mechanical prophylaxis vs. no prophylaxis, Evidence Table 7. Six studies comparing low-dose heparin vs. no prophyl- axis, Evidence Table 8. Four studies using gender as a risk factor, Evidence Table 9. Eight studies using head injury as a risk factor, Evidence Table 10. Twelve studies using long-bone fracture as a risk factor, Evidence Table 11. Eight studies using pelvic fracture as a risk factor, Evidence Table 12. Ten studies using spinal fracture as a risk factor, Evidence Table 13. Five studies using spinal-cord injury as a risk factor, Evidence Table 14. Ten studies evaluating age of patients with and without deep venous thrombosis, Evidence Table 15. Nine studies evaluating Injury Severity Score in patients with and without deep venous thrombosis, Evidence Table 16. Three studies evaluating blood transfusion in patients with and without deep venous thrombosis, Evidence Table 17. Three studies comparing methods of screening for deep venous thrombosis, Evidence Table 18. Six studies reporting on pulmonary embolism and fatal pulmonary embolism after vena cava filter placement _________________________________________________________________________________ 14biblio.doc Microsoft Word® Document MS Word® 97 SR-1 99KB 14 pages Contents: Bibliography _________________________________________________________________________________ 15cover.doc Microsoft Word® Document MS Word® 97 SR-1 19KB 2 pages Contents: Cover Page for Appendixes _________________________________________________________________________________ 16appa.doc Microsoft Word® Document MS Word® 97 SR-1 108KB 9 pages Contents: Appendix A: Study Design _________________________________________________________________________________ 17appb.doc Microsoft Word® Document MS Word® 97 SR-1 23KB 2 pages Contents: Appendix B: Contributor and Peer Reviewers _________________________________________________________________________________ 18appc.doc Microsoft Word® Document MS Word® 97 SR-1 23KB 2 pages Contents: Appendix C: Acronyms and Abbreviations _________________________________________________________________________________ 19fig2&3.jpg Compressed Bitmap File Generic graphic 86KB 1 page Contents: Figures 2 and 3. Decision tree for diagnosis and treatment of venous thromboembolism _________________________________________________________________________________ 20fig20.jpg Compressed Bitmap File Generic graphic 112KB 1 page Contents: Figure 20. Cost of VT prophylaxis with LDH vs. no prophylaxis _________________________________________________________________________________ 21fig21.jpg Compressed Bitmap File Generic graphic 116KB 1 page Contents: Figure 21. Cost of VT prophylaxis with mechanical vs. no prophylaxis _________________________________________________________________________________ 22fig22.jpg Compressed Bitmap File Generic graphic 136KB 1 page Contents: Figure 22. Cost of VT prophylaxis with LMWH vs. no prophylaxis _________________________________________________________________________________
AHRQ Publication No. 01-E004
Current as of November 2000
Internet Citation:
Prevention of Venous Thromboembolism After Injury. File Inventory, Evidence Report/Technology Assessment Number 22. AHRQ Publication No. 01-E004, November 2000. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/clinic/vtinv.htm
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