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Microbial Production of a Novel Compount, 7,10-Dihydroxy-8-Octadecenoic Acid from Oleic Acid
Patent Number: 5900496
Docket Number: 19896
Serial Number: 8665600
Date Patented: 05/04/1999
Agency:
Agricultural Research Service
Date Filed:
June 18, 1996
Abstract:
The invention involves the enzymatic conversion of oleic acid derived from oilseeds, such as sunflower, safflower, soybean and corn, to the compound, 7,10-dihydroxy-8-octadecenoic acid (DOD). The invention uses a newly-discovered strain of Pseudomonas bacterium (NRRL B-18602) to produce an optically-active product. The production of DOD is unique because it involves a hydroxylation at two positions and a rearrangement of the double bond of the substrate molecule. The new multi functional, long-chain aliphatic acid has potential use as a plasticizer and as a source of intermediates in the synthesis of specialty chemicals.
Inventors:
| Ching T. Hou |
| USDA, ARS, NCAUR |
| Peoria, IL |
| (309) 681-6531 |
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| (309) 681-7814 -- fax |
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Industry Keywords:
specialty chemicals, biotechnology, Pseudomonas, microbiology, enzymatic, fermentation, new uses, oleic acid, soybean, corn, sunflower, safflower
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