SHAM-Sensitive Terminal Oxidase Gene From Xylose-Fermenting Yeast

Agency:

Forest Service

Technology Description:

This invention discloses a SHAM-sensitive terminal oxidase (STO) gene from the xylose-fermenting yeast Pichia stipitis, which, when disrupted through mutation, results in an enhanced fermentation of xylose to ethanol by the yeast. The use of ethanol as an alternative energy and fuel source has become increasingly prevalent in recent years and it is estimated that future needs will greatly outweigh the current production levels. Due to this, it has become necessary to focus on fermentation methods that utilize sugars from alternative biomass from that currently used. With this invention, a novel method of producing ethanol at sufficient levels for use as a fuel source has been established.

Reference:

Please refer to USPN 6,391,599, which issued on May 21, 2002.

Inventors:

Thomas W. Jeffries USDA Forest Service Forest Products Laboratory One Gifford Pinchot Drive Madison, WI 53705 (608) 231-9453

Nian-Qing Shi (Non-Forest Service)