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Summaries of Newsworthy Clinical Trial Results

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11.  Largest-Yet Mesothelioma Study Shows Survival Benefit with New Drug
(Updated: 05/20/2002) - Researchers with the largest phase III trial to date for mesothelioma, an aggressive cancer affecting the lining of the lung, reported results showing that patients on a new chemotherapy drug regimen live longer and have less pain than those on an older drug. The findings were announced at the annual meeting of the American Society of Clinical Oncology meeting in Orlando, Fla., on May 20, 2002.

12.  No Clear Winner Among Multidrug Treatments for Non-Small Cell Lung Cancer
(Posted: 02/19/2002) - A comparison of four multidrug regimens used to treat advanced (metastatic) non-small cell lung cancer found that no one regimen offered a significant survival benefit over another, researchers with the Eastern Cooperative Oncology Group reported in the January 10, 2002, issue of the New England Journal of Medicine.

13.  Uncertainty Still Surrounds Use of Vitamin A in Lung Cancer
(Posted: 04/18/2001) - In a major clinical trial exploring treatment of stage I non-small-cell lung cancer, the vitamin-A-type drug isotretinoin failed to protect patients from developing more tumors in the lungs and upper airways. The trial results were reported in the April 18, 2001, issue of the Journal of the National Cancer Institute.

14.  Chemotherapy and Advanced Lung Cancer: Less Treatment May Be Enough
(Posted: 03/14/2001) - Patients with advanced non-small cell lung cancer are often given six courses of chemotherapy. Now a March 2001 British study indicates that three rounds of treatment may offer the same benefit to patients as six or more.

15.  Adding Chemotherapy to Radiation After Surgery Adds No Benefit in Lung Cancer
(Posted: 10/26/2000) - Adding chemotherapy to radiation therapy does not prolong survival in operable, non-small cell lung cancer, according to a study in the Oct. 26, 2000, issue of the New England Journal of Medicine.
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