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A Growing Threat
Disease-causing microbes that have become resistant to drug therapy
are an increasing public health problem. Tuberculosis, gonorrhea,
malaria, and childhood ear infections are just a few of the diseases
that have become hard to treat with antibiotic drugs. Part of the
problem is that bacteria and other microorganisms that cause infections
are remarkably resilient and can develop ways to survive drugs meant
to kill or weaken them. This antibiotic resistance, also
known as antimicrobial resistance or drug resistance,
is due largely to the increasing use of antibiotics. Other facts:
- Though food-producing animals are given antibiotic drugs for
important therapeutic, disease prevention or production reasons,
these drugs can cause microbes to become resistant to drugs used
to treat human illness, ultimately making some human sicknesses
harder to treat.
- About 70 percent of bacteria that cause infections in hospitals
are resistant to at least one of the drugs most commonly used
to treat infections.
- Some organisms are resistant to all approved antibiotics and
must be treated with experimental and potentially toxic drugs.
- Some research has shown that antibiotics are given to patients
more often than guidelines set by federal and other healthcare
organizations recommend. For example, patients sometimes ask their
doctors for antibiotics for a cold, cough, or the flu, all of
which are viral and don't respond to antibiotics. Also, patients
who are prescribed antibiotics but don't take the full dosing
regimen can contribute to resistance.
- Unless antibiotic resistance problems are detected as they emerge,
and actions are taken to contain them, the world could be faced
with previously treatable diseases that have again become untreatable,
as in the days before antibiotics were developed.
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General Background
"The Battle of
the Bugs: Fighting Antibiotic Resistance" (FDA Consumer
article)
FDA Publishes Final
Rule to Require Labeling About Antibiotic Resistance (FDA Press
Release)
HHS,
Public Health Partners Unveil New Campaign to Promote Awareness
of Proper Antibiotic Use (DHHS Release, Sept. 17, 2003)
"Antibiotic Resistance
from Down on the Farm" (FDA Consumer article)
"Miracle Drugs vs.
Superbugs" (FDA Consumer article)
Antibiotic
resistance fact sheet (National Institutes of Health)
Drug information
(FDA Center for Drug Evaluation and Research)
Prevention
tips for Consumers (Centers for Disease Control and Prevention)
Questions
and answers (CDC)
Antibiotic-Resistant
Bacteria (Washington state health dept.)**
When the Antibiotics
Quit Working... (University of Wisconsin)**
Veterinary/Industry Information
FDA Outlines New
Approach To Preventing Antimicrobial Resistance from Use of Animal
Drugs (Oct. 23, 2003)
"Human Health Impact and Regulatory Issues Involving Antimicrobial
Resistance in the Food Animal Production Environment"
(FDA National Center for Toxicological Research)
HTML
PDF
FDA Center for
Veterinary Medicine
antibiotic resistance information
Antibiotic resistance
monitoring (NARMS--National Antimicrobial Resistance Monitoring
System)
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