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  • The NCI Center for Bioinformatics (NCICB) Overview

    In order to capitalize on extraordinary opportunities the NCI has launched an extensive series of research initiatives. These initiatives serve as nucleation points for the larger collection of investigator-initiated cancer research efforts. The NCI initiatives are diverse. They are also highly interdependent. Each domain has important intersections with other research areas.

    NCI Center for Bioinformatics NCI Center for Bioinformatics
    Mouse Models Molecular Signatures
    caCORE
    Clinical Trials Cancer Genomics

    Each NCI initiative requires informatics support. The majority of this support entails the development of infrastructure components and tools that largely affect the proximate research activities for that initiative. However, because of their interdependence, each effort also consumes and generates information of significance to other initiatives, and to the broader cancer research community. In order to maximize the utility of information obtained within an effort and its exchange between initiatives coordination is required. This coordination is needed for efficiency in building infrastructure and to assure the existence of conduits of electronic communication. The goal of this coordination is to expand the insights that can be obtained by the cancer research community.

    To address these informatics needs the NCI has established the Center for Bioinformatics (NCICB). Its mission is to provide bioinformatics support and integration of NCI supported research initiatives. To achieve this goal the NCICB has been constituted as a network of Initiative-Specific Core Modules connected through intelligent interfaces and coordinated through an NCI Core Module. Each Core Module has three inter-related missions: projects (development and support of production activities related to the initiative), service (facilitating research within the initiative), and research (within the initiative's defined domain).

    mission Mission
    The NCICB's charge and functional statement.
    modules Module Components
    Description of components provided by the NCICB to support the research initiatives.
    Context NCICB and NCI Informatics
    Description of the roles of the NCICB in the context of the larger efforts of NCI.
    personnel Staff
    Listing of NCICB staff and other NCI personnel providing support to NCICB efforts.

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