NIDA Research Monograph, Number 121 [Printed in 1992]
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Download Monograph121.pdf - Buprenorphine: An Alternative Treatment for Opioid Dependence (1.3 MB)
Introduction-----1
Jack O. Blaine
Buprenorphine-Background to Its Development as a Treatment for Opiate Dependence-----5
John W. Lewis and Donald Walter
Behavioral Pharmacology of Buprenorphine: Issues Relevant to Its Potential in Treating Drug Abuse-----12
James H. Woods, Charles P. France, and Gail D. Winger
Assessment of Buprenorphine in a Drug Discrimination Procedure in Humans-----28
George E. Bigelow and Kenzie L. Preston
Human Laboratory Studies of Buprenorphine-----38
Jack H. Menedelson and Nancy K. Mello
Primate Studies of the Behavioral Pharmacology of Buprenorphine-----61
Nancy K. Mello and Jack H. Mendelson
Phase II Clinical Trials of Buprenorphine: Detoxification and Induction Onto Naltrexone-----101
Thomas R. Kosten, Charles Morgan, and Herbert D. Kleber
Development of Buprenophine for the Treatment of Opioid Dependence-----120
Rolley E. Johnson and Paul J. Fudala
List of NIDA Research Monographs-----142
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