NIDA Research Monograph, Number 96 [Printed in 1990]
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Download Monograph96.pdf - Drugs of Abuse: Chemistry, Pharmacology, Immunology, and AIDS (2.4 MB)
Table of Contents
Introduction-----1
Phuong Thi Kim Pham
The Bivalent Ligand Approach in the Design of Highly Selective Opioid Receptor Antagonists-----3
Philip S. Portoghese
Opium Alkaloids and Affinity Labels-----21
Sydney Archer, Jean Bidlack, and G. Keith Mulholland
Novel Thebainelike Morphinandienes and Their Diels-Alder Adducts-----35
Leendert Maat
Opioid Antagonists: Structure Activity Relationships-----50
Dennis M. Zimmerman and J. David Leander
Effect of Fluorine Substitution on the Anti-HIV Activity of Dideoxynucleosides-----61
Victor E. Marquez
Opiate Antagonists and Anti-HIV Agents-----80
Elliot F. Hahn
Classical and Nonclassical Cannabinoids: Mechanism of Action-Brain Binding-----100
Allyn C. Hewlett, M. Ross Johnson, and Lawrence S. Melvin
Cocaine Receptor-Design of Ligands-----112
F.I. Carroll, Abraham Philip, and Anita H. Lewin
Structural and Functional Similarities of Opiate Receptors of Neural and Immune Origin-----122
Daniel J.J. Carr and J. Edwin Blalock
Immunomodulatory Effects of Chronic Morphine Treatment: Pharmacologic and Mechanistic Studies-----131
Henry U. Bryant, Edward W. Bernton, and John W. Holaday
Morphine-Induced Immune Modulation: Does It Predispose to HIV Infection?-----150
Prince Kumar Arora
A Murine Retrovitus Model for Studies of the Role of Cofactors and Ethanol in AIDS Development-----166
Ronald R. Watson
Drug Abuse and AIDS: Causes for the Connection-----181
Robert M. Donahoe
Immune Function in Heroin Addicts and Former Heroin Addicts in Treatment: Pre- and Post-AIDS Epidemic-----192
Mary Jeanne Kreek
Opioid Peptides, Receptors, and Immune Function-----220
Hemendra N. Bhargava
Summary of Recommendations for Future Research-----234
Louis Harris
List of NIDA Research Monographs-----237
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