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Science for the Brain
The nation's leading supporter of biomedical research on disorders of the brain and nervous system


Funding Resources

Program Areas
  • Neurodegeneration

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National Institutes of
Health

  Neurodegeneration

Scientific Area of Research

Neuronal cell death, how protein aggregation damages neurons, and the interaction of genes and the environment in the etiology of neurodegenerative diseases.

2004 Event Series Calendar
2003 Event Series Calendar

Funding Opportunities

Current Neurodegeneration Funding Announcements

Archived Neurodegeneration Funding Announcements

Additional Information

Mission:
The Neurodegeneration cluster portfolio consists of research on the adult onset neurodegenerative diseases of all types, broadly focusing on the pathogenesis, treatment and prevention. Necessarily included is research on the normal structure and function of the neural systems to more readily identify intervention strategies. The role of the programmatic team is to develop, implement and manage these research programs and to promote the translation of research findings into clinical practice.

  • Encourage and Support Research designed to obtain a clearer understanding of neuronal cell death.

  • Neurodegenerative diseases in the portfolio include:
    • Parkinson's Disease, including early onset forms (Autosomal recessive juvenile Parkinson's; ARJP), Lewy body dementias, and general synucleinopathies.
    • Alzheimer's disease, including frontotemporal dementias (FTD), corticobasal degeneration (CBD), progressive supranuclear palsy (PSP), and general tauopathies and amyloidopathies.
    • Amyotrophic Lateral Sclerosis, including adult-onset motor neuron disease.
    • Huntington's disease, including spino-cerebellar ataxias and adult onset trinucleotide repeat disorders.

  • Encourage and Support Research to describe how protein aggregation damages neurons.

  • Examples:
    Amyloid plaques of Alzheimer's disease
    Lewy bodies of Parkinson's disease
    Prion protein aggregates in Creutzfeldt-Jakob disease

  • Encourage and Support Research on the interaction of genes and the environment in the etiology of neurodegenerative disease.


    Initiatives:
    Implementation of the Provisions of the "Udall Bill," including Morris K. Udall Centers for Excellence in Parkinson's Disease
    Scientists Training Program
    National Genetic Resource Center for Neurological Disorders
    National Education Program And Clearinghouse
    Trans-NIH Planning and Coordination
    Biennial Research Planning Conference
    Parkinson's Disease Research Web Site
  • Additional Links

    Information on Stem Cell Research
    Compounds Tested by NINDS Drug Screening Consortium

    Workshops and Summaries

    Conferences from 2004

    Conferences from 2003

    Conferences from 2002

    Conferences from 2001

    Conferences from Previous Years

    Personnel

    Diane D. Murphy, Ph.D.
    Program Director
    dm152o@nih.gov

    Eugene Oliver, Ph.D.
    Program Director
    eo11c@nih.gov

    Paul Sheehy, Ph.D.
    Program Director
    ps32h@nih.gov

    Lynn Morin
    Program Analyst
    bm201h@nih.gov

    Liza Saavedra
    Program Assistant
    ll196k@nih.gov

    Audrey Warner
    Program Assistant
    aw46m@nih.gov

    Address

    Neurodegeneration
    Neuroscience Center
    6001 Executive Blvd.
    Bethesda, MD 20892-9520
    For courier service only, use Rockville, MD 20852
    Phone:(301) 496-5680
    Fax: (301) 480-1080


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