Evidence Report/Technology Assessment Number 56

Management of Clinically Inapparent Adrenal Mass

File Inventory


Prepared by:

New England Medical Center Evidence-based Practice Center
Joseph Lau, M.D.
   EPC/Project Director
Ethan Balk, M.D., M.P.H.
   Assistant Project Director
Michael Rothberg, M.D.
John P.A. Ioannidis, M.D.
Deirdre DeVine, M.Litt.
Priscilla Chew, M.P.H.
Bruce Kupelnick, B.A.
Kimberly Miller, B.A.
   Investigators


File Name		Description			Software	Version	File	Size
__________________________________________________________________________________________________________
01front.doc		Microsoft Word® Document	MS Word®	2002	32KB	3 pages
Contents: Title Page, Preface

02abstr.doc		Microsoft Word® Document	MS Word®	2002	29KB	2 pages
Contents: Structured Abstract

03conts.doc		Microsoft Word® Document	MS Word®	2002	131KB	5 pages
Contents: Table of Contents

04summ.doc		Microsoft Word® Document	MS Word®	2002	84KB	6 pages
Contents: Summary: Overview; Reporting the Evidence; Methods; Findings; Future Research

05chap1.doc		Microsoft Word® Document	MS Word®	2002	100KB	7 pages
Contents: Chapter 1. Introduction: Overview; Clinically Inapparent Adrenal Mass; 
Survival for Adrenal Cortical Carcinoma; Management of Adrenal Incidentaloma

06chap2.doc		Microsoft Word® Document	MS Word®	2002	61KB	8 pages
Contents: Chapter 2. Methods: Key Questions Addressed in this Report; Definition of 
Adrenal Incidentaloma; Literature Search; Study Selection; Summarizing the Literature

07chap3.doc		Microsoft Word® Document	MS Word®	2002	1.5MB	56 pages
Contents: Chapter 3. Results: Findings for Specific Questions: Question 1. What are the 
causes and prevalence of clinically inapparent adrenal masses?; Question 2. What is the 
diagnostic accuracy (sensitivity, specificity) of evaluation modalities (FNA/biopsy, 
CT, MRI, US, biochemical tests) used to differentiate adrenal masses (adrenal carcinoma, 
pheochromocytoma, adenoma, adrenal hyperplasia, etc.)?; Question 3. What are the surgical 
complication rates for various approaches used to excise adrenal masses; specifically 
laparoscopic, transabdominal, and retroperitoneal approaches?; Question 4. What are the 
patient outcomes after surgical excision of adrenocortical carcinoma (morbidity and 
mortality)?; Question 5. What evidence is there to support the use of periodic biochemical 
and imaging studies to follow untreated adrenal masses?

08chap4.doc		Microsoft Word® Document	MS Word®	2002	32KB	3 pages
Contents: Chapter 4. Conclusions

09chap5.doc		Microsoft Word® Document	MS Word®	2002	29KB	2 pages
Contents: Chapter 5. Future Research: The Need to Understand Issues Related to the 
Diagnosis of Incidentaloma; Diagnostic Tests to Evaluate Adrenal Mass; Assessment of 
Surgical Techniques for Adrenalectomy; Follow up of Untreated Adrenal Masses; 
The Need for an International Registry of Adrenal Incidentaloma

10refs.doc		Microsoft Word® Document	MS Word®	2002	64KB	10 pages
Contents: References

11etbl1.doc		Microsoft Word® Document	MS Word®	2002	352KB	23 pages
Contents: Evidence Table 1. Prevalence of pathologies of adrenal incidentaloma

12etbl2.doc		Microsoft Word® Document	MS Word®	2002	649KB	36 pages
Contents: Evidence Table 2. Diagnostic performance of tests to evaluate adrenal masses

13etbl3.doc		Microsoft Word® Document	MS Word®	2002	142KB	15 pages
Contents: Evidence Table 3. Risk of complications from fine needle aspiration biopsy 
of the adrenal gland

14etbl4.doc		Microsoft Word® Document	MS Word®	2002	45KB	1 page
Contents: Evidence Table 4. Cohort/series of surgical complications of open transperitoneal 
adrenalectomy

15etbl5.doc		Microsoft Word® Document	MS Word®	2002	125KB	6 pages
Contents: Evidence Table 5. Cohort/series of surgical complications of open retroperitoneal 
adrenalectomy

16etbl6.doc		Microsoft Word® Document	MS Word®	2002	92KB	7 pages
Contents: Evidence Table 6. Surgical complications of comparative open adrenalectomy 
techniques

17etbl7.doc		Microsoft Word® Document	MS Word®	2002	336KB	24 pages
Contents: Evidence Table 7. Surgical complications of transperitoneal laparoscopic 
adrenalectomy

18etbl8.doc		Microsoft Word® Document	MS Word®	2002	157KB	10 pages
Table 13. Evidence Table 8. Surgical complications of retroperitoneal laparoscopic 
adrenalectomy

19etbl9.doc		Microsoft Word® Document	MS Word®	2002	373KB	33 pages
Contents: Evidence Table 9. Surgical complications of open vs. endoscopic adrenalectomy 
techniques

20etbl10.doc		Microsoft Word® Document	MS Word®	2002	142KB	11 pages
Contents: Evidence Table 10. Surgical complications of comparative endoscopic adrenalectomy 
techniques

21etbl11.doc		Microsoft Word® Document	MS Word®	2002	358KB	36 pages
Contents: Evidence Table 11. Morbidity/mortality of adrenocortical carcinoma after 
surgical excision

22etbl12.doc		Microsoft Word® Document	MS Word®	2002	72KB	7 pages
Contents: Evidence Table 12. Follow-up studies of incidentally discovered untreated 
adrenal masses by established protocol

23etbl13.doc		Microsoft Word® Document	MS Word®	2002	77KB	4 pages
Contents: Evidence Table 13. Follow-up studies of incidentally discovered untreated 
adrenal masses without established protocol

24biblio.doc		Microsoft Word® Document	MS Word®	2002	20KB	1 page
Contents: Bibliography

25appa.doc		Microsoft Word® Document	MS Word®	2002	29KB	3 pages
Contents: Appendix A. Literature Search Strategies

26appb.doc		Microsoft Word® Document	MS Word®	2002	25KB	2 pages
Contents: Appendix B. Acknowledgements

27appc.doc		Microsoft Word® Document	MS Word®	2002	49KB	7 pages
Contents: Appendix C. Biases of Case Series and Potential Hazards in Making Recommendations 
from Case Series Reports

28appd.doc		Microsoft Word® Document	MS Word®	2002	47KB	2 pages
Contents: Appendix D. Acronyms and Abbreviations
__________________________________________________________________________________________________________

AHRQ Publication No. 02-E014
Current as of May 2002


Internet Citation:

Management of Clinically Inapparent Adrenal Mass. File Inventory, Evidence Report/Technology Assessment Number 56. AHRQ Publication No. 02-E014, May 2002. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/clinic/admasinv.htm


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