Prepared by:
RTI International-University of North Carolina
Evidence-based Practice Center
Meera Viswanathan, Ph.D.
Valerie J. King, M.D., M.P.H.
Clay Bordley, M.D., M.P.H.
Amanda A. Honeycutt, Ph.D.
John Wittenborn, B.A., B.S.
Anne M. Jackman, M.S.W.
Sonya F. Sutton, B.S.P.H.
Kathleen N. Lohr, Ph.D.
File Name Description Software Version File Size ________________________________________________________________________________________________ 01front.doc Microsoft Word® Document MS Word® 2002 51KB 5 pages Contents: Cover, Title Page, Preface ________________________________________________________________________________________________ 02ackn.doc Microsoft Word® Document MS Word® 2002 126KB 1 page Contents: Acknowledgments ________________________________________________________________________________________________ 03abstr.doc Microsoft Word® Document MS Word® 2002 132KB 2pages Contents: Structured Abstract ________________________________________________________________________________________________ 04conts.doc Microsoft Word® Document MS Word® 2002 121KB 4pages Contents: Table of Contents ________________________________________________________________________________________________ 05summ.doc Microsoft Word® Document MS Word® 2002 154KB 8 pages Contents: Summary: Overview, Reporting the Evidence, Methodology, Findings, Future Research ________________________________________________________________________________________________ 06chap1.doc Microsoft Word® Document MS Word® 2002 164KB 8 pages Contents: Chapter 1. Introduction: Background, Clinical Issues, Justification for this Evidence Report, Key Questions and Causal Pathways, Organization of this Report ________________________________________________________________________________________________ 07fig1.doc Microsoft Word® Document MS Word® 2002 132KB 1 page Contents: Figure 1. Diagnosis and Treatment of Bronchiolitis Among Infants and Children ________________________________________________________________________________________________ 08fig2.doc Microsoft Word® Document MS Word® 2002 133KB 1 page Contents: Figure 2. Effectiveness and Costs of Respiratory Syncytial Virus Prophylaxis of Bronchiolitis for Infants and Children ________________________________________________________________________________________________ 09chap2.doc Microsoft Word® Document MS Word® 2002 161KB 8 pages Contents: Chapter 2. Methodology: Literature Review Methods, Data Collection, Analysis Strategy ________________________________________________________________________________________________ 10tbl1.doc Microsoft Word® Document MS Word® 2002 132KB 1 page Contents: Table 1. Management of Bronchiolitis in Infants and Children: Inclusion and Exclusion Criteria ________________________________________________________________________________________________ 11tbl2.doc Microsoft Word® Document MS Word® 2002 134KB 1 page Contents: Table 2. Management of Bronchiolitis in Infants and Children: Search Terms ________________________________________________________________________________________________ 12tbl3.doc Microsoft Word® Document MS Word® 2002 131KB 1 page Contents: Table 3. Electronic Databases for Literature Searches ________________________________________________________________________________________________ 13fig3.doc Microsoft Word® Document MS Word® 2002 150KB 1 page Contents: Figure 3. Cost Effectiveness Decision Tree ________________________________________________________________________________________________ 14chap3.doc Microsoft Word® Document MS Word® 2002 378KB 33 pages Contents: Chapter 3. Results: Key Question 1: Effectiveness of Diagnostic Tools for Diagnosing Bronchiolitis in Infants and Children ________________________________________________________________________________________________ 15tbl4.doc Microsoft Word® Document MS Word® 2002 139KB 1 page Contents: Table 4. Studies Examining the Accuracy of Virologic Tests ________________________________________________________________________________________________ 16tbl5.doc Microsoft Word® Document MS Word® 2002 149KB 2 pages Contents: Table 5. Studies Measuring Predictors of Disease Severity ________________________________________________________________________________________________ 17tbl6.doc Microsoft Word® Document MS Word® 2002 163KB 3 pages Contents: Table 6. Use of Chest X-rays for Diagnosis of Bronchiolitis ________________________________________________________________________________________________ 18tbl7.doc Microsoft Word® Document MS Word® 2002 149KB 1 page Contents: Table 7. Studies Examining Complete Blood Counts Performed ________________________________________________________________________________________________ 19tbl8.doc Microsoft Word® Document MS Word® 2002 182KB 1 page Contents: Table 8. Results of IMpact RSV Trial ________________________________________________________________________________________________ 20tbl9.doc Microsoft Word® Document MS Word® 2002 200KB 2 pages Contents: Table 9. RSV Hospitalization Rates ________________________________________________________________________________________________ 21tbl10.doc Microsoft Word® Document MS Word® 2002 142KB 1 page Contents: Table 10. Cost Estimates Used in Analyses ________________________________________________________________________________________________ 22tbl11.doc Microsoft Word® Document MS Word® 2002 141KB 1 page Contents: Table 11. 2001 Cost Per Hospitalization Avoided ________________________________________________________________________________________________ 23chap4.doc Microsoft Word® Document MS Word® 2002 166KB 6 pages Contents: Chapter 4. Conclusions: Diagnosis, Treatment, Prophylactic Therapy, Racial and Ethnic Subpopulations ________________________________________________________________________________________________ 24tbl12.doc Microsoft Word® Document MS Word® 2002 174KB 2 pages Contents: Table 12. Summary of Evidence for Treatment of Bronchiolitis ________________________________________________________________________________________________ 25tbl13.doc Microsoft Word® Document MS Word® 2002 142KB 1 page Contents: Table 13. Summary of Evidence for Prophylaxis of Bronchiolitis ________________________________________________________________________________________________ 26chap5.doc Microsoft Word® Document MS Word® 2002 135KB 5 pages Contents: Chapter 5. Future Research: Priorities for Further Research, General Guidelines for Further Research ________________________________________________________________________________________________ 27refs.doc Microsoft Word® Document MS Word® 2002 164KB 8 pages Contents: References ________________________________________________________________________________________________ 28gloss.doc Microsoft Word® Document MS Word® 2002 187KB 4 pages Contents: Glossary for Evidence Tables ________________________________________________________________________________________________ 29etbls.doc Microsoft Word® Document MS Word® 2002 1.5MB 148 pages Contents: Evidence Tables: Evidence Table 1. Nebulized Epinephrine vs. Nebulized Saline Placebo Evidence Table 2. Subcutaneous Epinephrine vs. Saline Placebo Evidence Table 3. Nebulized Epinephrine vs. Nebulized Bronchodilators (Salbutamol or Albuterol) Evidence Table 4. Nebulized Bronchodilators (Salbutamol or Albuterol) vs. Oral Bronchodilators, Nebulized Ipratropium Bromide, or Saline Placebo or No Treatment Evidence Table 5. Nebulized Salbutamol or Albuterol plus Nebulized Ipratropium Bromide vs. Bronchodilators or Ipratropium Bromide Alone and/or Saline Placebo Evidence Table 6. Oral Corticosteroids vs. Placebo, With or Without Bronchodilators Evidence Table 7. Parenteral Dexamethasone vs. Placebo Evidence Table 8. Nebulized Corticosteroids vs. Placebo or Usual Care Evidence Table 9. Ribavirin vs. Placebo Evidence Table 10. Antibiotics vs. No Treatment or Other Antibiotics Evidence Table 11. RSVIG IV as Treatment for Bronchiolitis Evidence Table 12. Other Miscellaneous Treatments for Bronchiolitis Evidence Table 13. RSVIG IV vs. Placebo or Standard Care to Prevent RSV Bronchiolitis Evidence Table 14. Monoclonal Antibody for Prophylaxis of RSV Bronchiolitis Evidence Table 15. Vaccines to Prevent RSV Bronchiolitis ________________________________________________________________________________________________ 30appa.doc Microsoft Word® Document MS Word® 2002 268KB 18 pages Contents: Appendix A. Clinical Scales ________________________________________________________________________________________________ 31appb.doc Microsoft Word® Document MS Word® 2002 143KB 4 pages Contents: Appendix B. Abstract Review Form ________________________________________________________________________________________________ 32appc.doc Microsoft Word® Document MS Word® 2002 592KB 48 pages Contents: Appendix C. Final Abstraction Forms ________________________________________________________________________________________________ 33appd.doc Microsoft Word® Document MS Word® 2002 148KB 4 pages Contents: Appendix D. Quality Rating Form ________________________________________________________________________________________________
AHRQ Publication No. 03-E014
Current as of January 2003
Internet Citation:
Management of Bronchiolitis in Infants and Children. File Inventory, Evidence Report/Technology Assessment Number 69. AHRQ Publication No. 03-E014, January 2003. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/clinic/broncinv.htm
Return to Evidence-based Practice
Clinical Information
AHRQ Home Page
Department of Health and Human Services