Prepared by:
Tufts-New England Medical Center EPC, Boston, MA
Investigators
Ellen C. Perrin, M.D., M.A.
Cynthia H. Cole, M.D., M.P.H.
Deborah A. Frank, M.D.
Stephan R. Glicken, M.D.
Nicholas Guerina, M.D.
Kevin Petit, M.D.
Robert Sege, M.D., Ph.D.
MaryAnn V. Volpe, M.D.
EPC Staff
Joseph Lau, M.D., Director
Caroline A. McFadden, M.D., and Priscilla Chew M.P.H., Project Leaders
Deirdre DeVine, M.Litt., Project Manager
Kimberly Miller, B.A., Research Assistant
File Name Description Software Version File Size ________________________________________________________________________________________________ 01front1.doc Microsoft Word® Document MS Word® 2002 105KB 12 pages Contents: Title Page, Preface, Structured Abstract, Table of Contents ________________________________________________________________________________________________ 02summ.doc Microsoft Word® Document MS Word® 2002 61KB 9 pages Contents: Summary: Overview, Causes of Failure to Thrive, Reporting the Evidence, Methodology, Findings, Future Research ________________________________________________________________________________________________ 03chap1.doc Microsoft Word® Document MS Word® 2002 38KB 6 pages Contents: Chapter 1. Introduction: Definitions; Causes and Effects of FTT; Association of FTT with Immunological Functioning; Association of FTT with Neurological Functioning; Growth Abnormalities; Other Associated Health Problems; Summary ________________________________________________________________________________________________ 04chap2.doc Microsoft Word® Document MS Word® 2002 64KB 6 pages Contents: Chapter 2. Methodology: Key Question Addressed in the Evidence Report; Search Strategies; Table 1. Outcomes and covariates studied; Study Selection; Covariates/Outcomes Considered; Abstraction; Reporting the Evidence; Evidence Tables; Summary Tables; Summarizing the Evidence of Individual Studies ________________________________________________________________________________________________ 05chap3.doc Microsoft Word® Document MS Word® 2002 422KB 26 pages Contents: Chapter 3. Results: Persistent Disorders of Growth Following Diagnosis of Failure to Thrive; Table 2. Studies of persistent anthropometric abnormalities following diagnosis of Failure to Thrive in developed countries; Table 3. Studies of persistent anthropometrics abnormalities in malnourished cases in developing countries; Associations of FTT with Immunologic/Infectious Outcomes; Table 4. Studies with associations of immunologic dysfunction or infectious diseases to Failure to Thrive & healthy comparison groups in developed countries; Table 5. Studies with associations of immunologic dysfunction or infectious diseases and malnourished cases compared to well-nourished controls in developing countries; Child Behavior Problems Associated with Failure to Thrive; Table 6. Studies with association of behavioral correlates to Failure to Thrive compared to healthy comparison groups in developed and developing countries; Developmental Disorders Associated with Failure to Thrive; Table 7. Studies with association of cognitive & neurological development to Failure to Thrive compared to healthy comparison groups in developed countries; Table 8. Studies with association cognitive & neurological development and malnourished cases compared to well-nourished controls in developing countries; Evidence that Failure to Thrive (FTT) is Associated with Other Clinical, Psychosocial and Family Factors ________________________________________________________________________________________________ 06chap4.doc Microsoft Word® Document MS Word® 2002 33KB 3 pages Contents: Chapter 4. Conclusions: Overview; Persistent Disorders of Growth; Association of FTT with Immunologic/Infectious Outcomes; Behavior Difficulties Associated with Failure to Thrive; Developmental Disorders Associated with Failure to Thrive; Evidence that Failure to Thrive is Associated with Other Clinical, Psychosocial and Family Factors ________________________________________________________________________________________________ 07chap5.doc Microsoft Word® Document MS Word® 2002 26KB 2 pages Contents: Chapter 5. Future Research ________________________________________________________________________________________________ 08refs.doc Microsoft Word® Document MS Word® 2002 38KB 3 pages Contents: References and Bibliography ________________________________________________________________________________________________ 09etbl1.doc Microsoft Word® Document MS Word® 2002 105KB 6 pages Contents: Evidence Table 1. Studies associating anthropometrics to Failure to Thrive cases compared to healthy control group in developed countries ________________________________________________________________________________________________ 10etbl2.doc Microsoft Word® Document MS Word® 2002 107KB 7 pages Contents: Evidence Table 2. Studies associating anthropometrics with malnourished patients compared to well-nourished control subjects in developing countries ________________________________________________________________________________________________ 11etbl3.doc Microsoft Word® Document MS Word® 2002 63KB 3 pages Contents: Evidence Table 3. Studies associating immunologic response or infectious diseases with Failure to Thrive patients compared to healthy control subjects in developed countries ________________________________________________________________________________________________ 12etbl4.doc Microsoft Word® Document MS Word® 2002 95KB 6 pages Contents: Evidence Table 4. Studies associating immunologic response or infectious diseases with malnourished patients compared to well-nourished control subjects in developing countries ________________________________________________________________________________________________ 13etbl5.doc Microsoft Word® Document MS Word® 2002 217KB 13 pages Contents: Evidence Table 5. Studies associating behavioral problems with Failure to Thrive patients compared to healthy control subjects in developed countries ________________________________________________________________________________________________ 14etbl6.doc Microsoft Word® Document MS Word® 2002 45KB 1 page Contents: Evidence Table 6. Study associating behavioral problems with malnourished patients compared to healthy control subjects in developing country ________________________________________________________________________________________________ 15etbl7.doc Microsoft Word® Document MS Word® 2002 182KB 12 pages Contents: Evidence Table 7. Studies associating cognitive & neurological development with Failure to Thrive patients compared to healthy control subjects in developed countries ________________________________________________________________________________________________ 16etbl8.doc Microsoft Word® Document MS Word® 2002 126KB 7 pages Contents: Evidence Table 8. Studies associating cognitive & neurological development with malnourished patients compared to well-nourished control subjects in developing countries ________________________________________________________________________________________________ 17etbl9.doc Microsoft Word® Document MS Word® 2002 165KB 13 pages Contents: Evidence Table 9. Studies associating other correlates / outcomes with Failure to Thrive patients compared to healthy control subjects in developed countries ________________________________________________________________________________________________ 18etbl10.doc Microsoft Word® Document MS Word® 2002 74KB 4 pages Contents: Evidence Table 10. Studies associating other correlates / outcomes with malnourished patients compared to well nourished control subjects in developing countries ________________________________________________________________________________________________ 19appa.doc Microsoft Word® Document MS Word® 2002 27KB 4 pages Contents: Appendix A. Literature Search Strategies ________________________________________________________________________________________________ 20appb.doc Microsoft Word® Document MS Word® 2002 139KB 5 pages Contents: Appendix B. Data Abstraction Form ________________________________________________________________________________________________ 21appc.doc Microsoft Word® Document MS Word® 2002 36KB 3 pages Contents: Appendix C. Acknowledgements ________________________________________________________________________________________________ 22appd.doc Microsoft Word® Document MS Word® 2002 25KB 2 pages Contents: Appendix D. Acronyms/Abbreviations ________________________________________________________________________________________________
AHRQ Publication No. 03-E026
Current as of March 2003
Internet Citation:
Criteria for Determining Disability in Infants and Children: Failure to Thrive. File Inventory, Evidence Report/Technology Assessment Number 72. AHRQ Publication No. 03-E026, March 2003. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/clinic/flthrinv.htm
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