Evidence Report/Technology Assessment Number 85

Hyperbaric Oxygen Therapy for Brain Injury, Cerebral Palsy, and Stroke

File Inventory


Prepared by:

Oregon Health & Science University Evidence-based Practice Center
Portland, Oregon

Marian S. McDonagh, Pharm.D., Principal Investigator
Susan Carson, M.P.H.
Joan S. Ash, M.L.S., M.B.A., Ph.D.
Barry S. Russman, M.D.
P. Zoë Stavri, Ph.D.
Kathryn Pyle Krages, A.M.L.S., M.A.
Mark Helfand, M.D., M.S., EPC Director


File Name	Description			Software	Version	File	Size
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01front.doc	Microsoft Word® Document	MS Word®	2002	67KB	4 pages
Contents: Title Page, Preface, Acknowledgments
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02abstr.doc	Microsoft Word® Document	MS Word®	2002	26KB	1 page
Contents: Structured Abstract
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03conts.doc	Microsoft Word® Document	MS Word®	2002	37KB	3 pages
Contents: Table of Contents
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04summ.doc	Microsoft Word® Document	MS Word®	2002	122KB	9 pages
Contents: Summary: Overview, Reporting the Evidence, Methodology, Findings, Future Research
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05chap1.doc	Microsoft Word® Document	MS Word®	2002	222KB	13 pages
Contents: Chapter 1. Introduction: Purpose, Background, Table 1. Glasgow Coma Scale
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06chap2.doc	Microsoft Word® Document	MS Word®	2002	120KB	8 pages
Contents: Chapter 2. Methodology: Technical Expert Advisory Group, Scope and Key Questions, 
Literature Search Strategy, Management of References, Assessment of Papers for Eligibility, 
Data Extraction, Assessment of Study Validity, Quality of the Body of Evidence, 
Synthesis of Results, Peer Review
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07chap3.doc	Microsoft Word® Document	MS Word®	2002	377KB	20 pages
Contents: Chapter 3. Results: 
Studies Meeting Eligibility Criteria;
1. Does HBOT improve mortality and morbidity in patients who have traumatic brain injury 
or nontraumatic brain injury, such as anoxic ischemic encephalopathy?
Table 2. Results for Study by Artu, Chacornac, and Deleuze; 
Table 3. Results of Study by Rockswold, Ford, et al
2. Does HBOT improve functional outcomes in patients who have cerebral palsy?
3. Does HBOT improve mortality and morbidity in patients who have suffered a stroke?
4. What are the adverse effects of using HBOT in brain injury, cerebral palsy, or stroke patients?
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08fig1.doc	Microsoft Word® Document	MS Word®	2002	49KB	1 page
Contents: Figure 1. HBOT Literature search results (Chapter 3)
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09fig2.doc	Microsoft Word® Document	MS Word®	2002	41KB	1 page
Contents: Contents: Figure 2. Study Design Algorithm (Chapter 3)
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10tbl4.xls	Microsoft Excel® Worksheet	MS Excel®	2002	17KB	1 page
Contents: Table 4. Controlled Trials of HBOT in Brain Injury (Chapter 3)
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11tbl5.xls	Microsoft Excel® Worksheet	MS Excel®	2002	17KB	1 page
Contents: Table 5. Controlled Trials of HBOT in Cerebral Palsy (Chapter 3)
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12tbl6.xls	Microsoft Excel® Worksheet	MS Excel®	2002	20KB	2 pages
Contents: Table 6. Controlled Trials of HBOT in Stroke (Chapter 3)
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13chap4.doc	Microsoft Word® Document	MS Word®	2002	85KB	2 pages
Contents: Chapter 4. Conclusions
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14chap5.doc	Microsoft Word® Document	MS Word®	2002	93KB	3 pages
Contents: Chapter 5. Future Research: Outcomes Studies, Studies of Diagnostic Tests 
and Intermediate Outcome Measures
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15refs.doc	Microsoft Word® Document	MS Word®	2002	134KB	8 pages
Contents: References
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16etbl1.xls	Microsoft Excel® Worksheet	MS Excel®	2002	25KB	6 pages
Contents: Evidence Table 1. Brain Injury Controlled Trial Data
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17etbl2.xls	Microsoft Excel® Worksheet	MS Excel®	2002	41KB	18 pages
Contents: Evidence Table 2. Brain Injury Observational Study Data
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18etbl3.xls	Microsoft Excel® Worksheet	MS Excel®	2002	21KB	4 pages
Contents: Evidence Table 3. Cerebral Palsy Controlled Trial Data
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19etbl4.xls	Microsoft Excel® Worksheet	MS Excel®	2002	23KB	6 pages
Contents: Evidence Table 4. Cerebral Palsy Observational Study Data
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20etbl5.xls	Microsoft Excel® Worksheet	MS Excel®	2002	28KB	9 pages
Contents: Evidence Table 5. Stroke Controlled Trial Data
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21etbl6.xls	Microsoft Excel® Worksheet	MS Excel®	2002	51KB	21 pages
Contents: Evidence Table 6. Stroke Observational Study Data
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22etbl7.xls	Microsoft Excel® Worksheet	MS Excel®	2002	63KB	24 pages
Contents: Evidence Table 7. Conference Proceedings and Abstract-only Study Data
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23etbl8.xls	Microsoft Excel® Worksheet	MS Excel®	2002	32KB	9 pages
Contents: Evidence Table 8. Quality Assessment of Controlled Studies
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24etbl9.xls	Microsoft Word® Document	MS Word®	2002	42KB	18 pages
Contents: Evidence Table 9. Quality Assessment of Observational Studies
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25biblio.doc	Microsoft Word® Document	MS Word®	2002	275KB	38 pages
Contents: Bibliography
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26appa.doc	Microsoft Word® Document	MS Word®	2002	47KB	2 pages
Contents: Appendix A. Indications for HBOT
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27appb.doc	Microsoft Word® Document	MS Word®	2002	52KB	5 pages
Contents: Appendix B. Research Team, Technical Expert Advisory Group, and Peer Reviewers
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28appc.doc	Microsoft Word® Document	MS Word®	2002	62KB	4 pages
Contents: Appendix C. Literature Search Strategies
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29appd.doc	Microsoft Word® Document	MS Word®	2002	45KB	3 pages
Contents: Appendix D. Quality Assessment Criteria
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30appe.doc	Microsoft Word® Document	MS Word®	2002	40KB	6 pages
Contents: Appendix E. Excluded Studies
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31appf.doc	Microsoft Word® Document	MS Word®	2002	26KB	2 pages
Contents: Appendix F. Studies with Intermediate Outcomes
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32appg.doc	Microsoft Word® Document	MS Word®	2002	29KB	2 pages
Contents: Appendix G. Unretrieved Studies
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33apph.doc	Microsoft Word® Document	MS Word®	2002	55KB	3 pages
Contents: Appendix H. Outcome Measures Used in HBOT Studies
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34acro.doc	Microsoft Word® Document	MS Word®	2002	23KB	2 pages
Contents: Abbreviations and Acronyms
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35gloss.doc	Microsoft Word® Document	MS Word®	2002	33KB	3 pages
Contents: Glossary of Terms
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36supp.doc	Microsoft Word® Document	MS Word®	2002	106KB	9 pages
Contents: Supplement. A Qualitative Assessment of Brain Injury, Cerebral Palsy, and Stroke 
Patient, Caregiver and Clinician Values of Outcomes
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37supfig.doc	Microsoft Word® Document	MS Word®	2002	26KB	1 page
Contents: Supplement Figure
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38supapp.doc	Microsoft Word® Document	MS Word®	2002	32KB	3 pages
Contents: Supplement Appendix. Interview Guides
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AHRQ Publication No. 04-E003
Current as of September 2003


Internet Citation:

Hyperbaric Oxygen Therapy for Brain Injury, Cerebral Palsy, and Stroke. File Inventory, Evidence Report/Technology Assessment Number 85. AHRQ Publication No. 04-E003, September 2003. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/clinic/hypoxinv.htm


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