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Pantoprazole

(pan toe' pra zole)

Brand name(s): Protonix

Why is this medication prescribed?

Pantoprazole is in a class of drugs called proton pump inhibitors. It is used for short-term treatment of heartburn and injury of the food pipe (esophagus) caused by backward flow of acid from the stomach. It decreases the amount of acid made in the stomach.

This medicine is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

How should this medicine be used?

Pantoprazole comes as an extended-release (long-acting) tablet to take by mouth. It is usually taken once a day, with or without food. Do not split, chew, or crush the tablets; swallow them whole. Pantoprazole is usually taken for 8 weeks, but your doctor may want you to take it for another 8 weeks if your esophagus has not healed. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take pantoprazole exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Symptoms of heartburn and injury to the esophagus should improve within 8 weeks of beginning pantoprazole. If your symptoms do not improve, or if they worsen, call your doctor. Once you and your doctor are sure the drug works for you, continue to take pantoprazole even if you feel well. Do not stop taking pantoprazole without talking to your doctor.

What special precautions should I follow?

Before taking pantoprazole,

• tell your doctor and pharmacist if you are allergic to lansoprazole, omeprazole, pantoprazole, rabeprazole, or any other drugs.
• tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially ampicillin, iron-containing medications (including multivitamins), ketoconazole (Nizoral), and vitamins and herbal products.
• tell your doctor if you have or have ever had liver disease.
• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking pantoprazole, call your doctor.
• If you are having surgery, including dental surgery, tell the doctor or dentist that you are taking pantoprazole.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed dose.

What side effects can this medication cause?

Although side effects from pantoprazole are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away:

• upset stomach
• headache
• diarrhea
• constipation
• stomach pain
• cough
• mild rash
• back, neck, or joint pain

If you experience any of the following symptoms, call your doctor immediately:

• chest pain
• difficulty breathing or swallowing
• itching
• weakness
• rash or hives
• severe skin rash with swelling and peeling
• swollen face, lower legs, or ankles
• vision changes
• vomiting
• yellowing of skin or eyes
• fever
• confusion
• slow movements
• speech problems
• increased salivation
• difficulty maintaining balance
• ringing in the ears
• sinus or upper respiratory tract infection

Pantoprazole may cause hyperglycemia (high blood sugar). If you have any of the following symptoms of hyperglycemia, call your doctor immediately:

• thirst
• dry mouth
• tiredness
• flushing
• dry skin
• frequent urination
• lost of appetite
• trouble breathing

What storage conditions are needed for this medicine?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

What other information should I know?

Pantoprazole may interfere with some laboratory tests for cholesterol and kidney function. If you are scheduled for any laboratory tests, tell your doctor that you take pantoprazole.

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check you response to pantoprazole.

Do not let anyone else take your medicine. Ask your pharmacist any questions you have about refilling your prescription.

Last Revised - 01/01/2003

American Society of Health-System Pharmacists, Inc. Disclaimer

The MedMaster™ Patient Drug Information database provides information copyrighted by the American Society of Health-System Pharmacists, Inc., Bethesda, Maryland Copyright© 2004. All Rights Reserved.

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