Description
What is cancer of the adrenal cortex?
What is cancer of the adrenal cortex?
Cancer of the adrenal cortex, a rare cancer, is a disease in which cancer
(malignant) cells are found in the adrenal cortex, which is the outside layer
of the adrenal gland. Cancer of the adrenal cortex is also called
adrenocortical carcinoma. There are two adrenal glands, one above each kidney
in the back of the upper abdomen. The adrenal glands are also called the
suprarenal glands. The inside layer of the adrenal gland is called the adrenal
medulla. Cancer that starts in the adrenal medulla is called pheochromocytoma
and is discussed in a separate PDQ patient information summary.
The cells in the adrenal cortex make important hormones that help the body work
properly. When cells in the adrenal cortex become cancerous, they may make too
much of one or more hormones, which can cause symptoms such as high blood
pressure, weakening of the bones, or diabetes. If male or female hormones are
affected, the body may go through changes such as a deepening of the voice,
growing hair on the face, swelling of the sex organs, or swelling of the
breasts. Cancers that make hormones are called functioning tumors. Many
cancers of the adrenal cortex do not make extra hormones and are called
nonfunctioning tumors.
A doctor should be seen if the following symptoms appear and won’t go away:
- pain in the abdomen,
- loss of weight without dieting, or
- weakness.
If there is
a functioning tumor, there may be symptoms or signs caused by too many
hormones.
If there are symptoms, a doctor will order blood and urine tests to see whether
the amounts of hormones in the body are normal. A doctor may also order a
computed tomography scan of your abdomen, a special x-ray that uses a computer
to make a picture of the inside of the abdomen. Other special x-rays may also
be done to tell what kind of tumor is present.
The chance of recovery (prognosis) depends on how far the cancer has spread
(stage) and on whether a doctor was able to surgically remove all of the
cancer.
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