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Childhood Cancer Trial Results
1. Improved Survival for Those With Ewing's Sarcoma
(Posted: 02/27/2003) - Addition of the drugs ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma significantly improved five-year survival in patients whose disease had not spread to other organs, according to the February 20, 2003, issue of the New England Journal of Medicine.
2. Alternate Drug Less Toxic, Less Effective Than Standard Treatment for ALL
(Posted: 05/20/2002) - Acute lymphoblastic leukemia (ALL) is the most common cancer in children. Now two new studies suggest that, given at the same dose, the standard E. coli form of the drug asparaginase -- a mainstay for more than 30 years in the treatment of ALL -- appears to be more effective, though more toxic, than another form known as Erwinia asparaginase.
3. High Doses of Chemotherapy Drug Lead to Better Survival for Children with Leukemia and Lymphoma
(Posted: 05/14/2001) - Higher doses of a common chemotherapy drug, methotrexate, may lead to less recurrences of a certain type of leukemia and lymphoma in children.
4. Less Chemotherapy Needed for Wilms' Tumor Patients
(Posted: 05/01/1999) - People with Wilms' tumor (a cancer of the kidney that most commonly occurs in children) can now receive fewer chemotherapy treatments with fewer side effects, according to a report in the January 1998 issue of the Journal of Clinical Oncology.
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