THURSDAY, Jan. 22 (HealthDayNews) -- Two proteins appear to work together in mice to prevent the formation of the brain plaques that are characteristic of Alzheimer's disease. Researchers at Washington University School of Medicine in St. Louis report in the Jan. 22 issue of Neuron that the proteins clusterin and apolipoprotein E (apoE) seem to orchestrate the removal of potentially hazardous molecules from the brain. Ironically, previous research implicated these same proteins in a key stage of brain plaque formation. "This is one of the first demonstrations in living animals that these proteins affect amyloid clearance," Dr. David H. Holtzman, head of the neurology department, says in a prepared statement. "Our findings suggest it is worthwhile to explore the use of drugs or therapies to alter or perhaps increase the expression of these proteins as a potential treatment for Alzheimer's disease," Holtzman says. More information Here's where you can learn more about Alzheimer's disease. (SOURCE: Washington University School of Medicine, news release, Jan. 21, 2004) Copyright © 2004 ScoutNews, LLC. All rights reserved. HealthDayNews articles are derived from various sources and do not reflect federal policy. healthfinder® does not endorse opinions, products, or services that may appear in news stories. For more information on health topics in the news, visit the healthfinder® health library. |