Prepared by:
Johns Hopkins Evidence-based Practice Center
Harold P. Lehmann, M.D., Ph.D.
Principal Investigator
John S. Andrews, M.D.
Co-Principal Investigator
Karen A. Robinson, M.Sc.
Victoria L. Holloway, M.D., M.P.H.
Steven N. Goodman, M.D., Ph.D.
Investigators
File Name Description Software Version File Size __________________________________________________________________________________________________________ 01v1frnt.wpd Corel WordPerfect® Document Corel WordPerfect® 6/7/8 38KB 9 pages Contents: Volume 1. Evidence Report and Appendixes: Title Page, Preface, Abstract, Table of Contents __________________________________________________________________________________________________________ 02v1summ.wpd Corel WordPerfect® Document Corel WordPerfect® 6/7/8 23KB 4 pages Contents: Summary: Overview, Reporting the Evidence, Methodology, Findings, Future Research __________________________________________________________________________________________________________ 03v1chp1.wpd Corel WordPerfect® Document Corel WordPerfect® 6/7/8 34KB 8 pages Contents: Chapter 1. Introduction: Epidemiology, Disease Biology and Natural History, Burden of Illness: Morbidity and Mortality, Psychological Impact and Quality of Life, Medical Costs, Treatment of Acne, Uses of This Report __________________________________________________________________________________________________________ 04v1chp2.wpd Corel WordPerfect® Document Corel WordPerfect® 6/7/8 3.8MB 9 pages Contents: Chapter 2. Methodology: Recruitment of Technical Experts, Patient Population, Questions, Causal Pathway, Literature Search Methods, Article Review, Peer Review __________________________________________________________________________________________________________ 05v1chp3.wpd Corel WordPerfect® Document Corel WordPerfect® 6/7/8 278KB 14 pages Contents: Chapter 3. Results: Summary of Literature: Literature Search and Abstract Review, Article Review, Description of the Acne Literature __________________________________________________________________________________________________________ 06v1chp4.wpd Corel WordPerfect® Document Corel WordPerfect® 6/7/8 535KB 80 pages Contents: Chapter 4. Results: Evidence: Summary of Evidence; Summaries of Treatment Classes: A. Cleansers, B. Keratolytic (topical), C. Anti-bacterial (topical), D. Anti-bacterial (topical)/Keratolytic (topical) Combinations, E. Retinoid (topical), F. Retinoid (topical)/Keratolytic, G. Retinoid (topical)/Anti-bacterial (topical), H. Anti-bacterial (oral), I. Anti-bacterial (oral)/Keratolytic (topical), J. Anti-bacterial (oral)/Retinoid (topical), K. Retinoid (oral), L. Retinoid (oral)/Keratolytic, M. Anti-androgen, N. Other; Psychological Outcomes; Compliance __________________________________________________________________________________________________________ 07v1chp5.wpd Corel WordPerfect® Document Corel WordPerfect® 6/7/8 63KB 8 pages Contents: Chapter 5. Conclusions: Characteristics of the Acne Clinical Research Literature, Overarching Conclusions, Answers to Specific Questions, Limitations __________________________________________________________________________________________________________ 08v1chp6.wpd Corel WordPerfect® Document Corel WordPerfect® 6/7/8 19KB 3 pages Contents: Future Research __________________________________________________________________________________________________________ 09v1refs.doc Microsoft Word® Document MS Word® 97 SR-1 90KB 15 pages Contents: References __________________________________________________________________________________________________________ 10v1appa.wpd Corel WordPerfect® Document Corel WordPerfect® 6/7/8 14KB 4 pages Contents: Appendix A. Technical Experts and Peer Reviewers __________________________________________________________________________________________________________ 11v1appb.wpd Corel WordPerfect® Document Corel WordPerfect® 6/7/8 34KB 4 pages Contents: Appendix B. Study Questions: Refinement by Experts __________________________________________________________________________________________________________ 12v1appc.wpd Corel WordPerfect® Document Corel WordPerfect® 6/7/8 10KB 2 pages Contents: Appendix C. Study Questions __________________________________________________________________________________________________________ 13v1appd.wpd Corel WordPerfect® Document Corel WordPerfect® 6/7/8 18KB 2 pages Contents: Appendix D. Study Questions: Expert Feedback __________________________________________________________________________________________________________ 14v1appe.wpd Corel WordPerfect® Document Corel WordPerfect® 6/7/8 7KB 2 pages Contents: Appendix E. Search Terms and Strategies __________________________________________________________________________________________________________ 15v1appf.wpd Corel WordPerfect® Document Corel WordPerfect® 6/7/8 11KB 2 pages Contents: Appendix F. Abstract Form __________________________________________________________________________________________________________ 16v1apg1.doc Microsoft Word® Document MS Word® 97 SR-1 78KB 8 pages Contents: Appendix G. Article Review Forms: Article Form __________________________________________________________________________________________________________ 17v1apg2.doc Microsoft Word® Document MS Word® 97 SR-1 53KB 6 pages Contents: Appendix G. Article Review Forms: Arm Form __________________________________________________________________________________________________________ 18v1apg3.doc Microsoft Word® Document MS Word® 97 SR-1 36KB 2 pages Contents: Appendix G. Article Review Forms: Outcome Form __________________________________________________________________________________________________________ 19v1apph.wpd Corel WordPerfect® Document Corel WordPerfect® 6/7/8 119KB 28 pages Contents: Appendix H. Included and Excluded Trials __________________________________________________________________________________________________________ 20v2frnt.wpd Corel WordPerfect® Document Corel WordPerfect® 6/7/8 18KB 5 pages Contents: Volume 2. Evidence Tables and Bibliography: Title Page, Table of Contents __________________________________________________________________________________________________________ 21v2desc.wpd Corel WordPerfect® Document Corel WordPerfect® 6/7/8 25KB 5 pages Contents: Description of the Evidence Tables: Summary Information, Presentation of Two- and Three-Arm vs. Multi-Arm Trials __________________________________________________________________________________________________________ 22v2indx.wpd Corel WordPerfect® Document Corel WordPerfect® 6/7/8 127KB 12 pages Contents: Index to Evidence Tables __________________________________________________________________________________________________________ 23etsumm.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 182KB 68 pages Contents: Summary Evidence Table. Trials included in the article review __________________________________________________________________________________________________________ 24eta1.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 6KB 1 page Contents: Evidence Table A.1. Articles/arms for class Cleanser (topical) __________________________________________________________________________________________________________ 25eta2.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 15KB 1 page Contents: Evidence Table A.2. Continuous outcomes for class Cleanser (topical) __________________________________________________________________________________________________________ 26eta3.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 14KB 1 page Contents: Evidence Table A.3. Discrete outcomes for class Cleanser (topical) __________________________________________________________________________________________________________ 27etb1.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 12KB 2 pages Contents: Evidence Table B.1. Articles/arms for class Keratolytic (topical) __________________________________________________________________________________________________________ 28etb2.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 25KB 4 pages Contents: Evidence Table B.2. Continuous outcomes for class Keratolytic (topical) __________________________________________________________________________________________________________ 29etb3.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 21KB 3 pages Contents: Evidence Table B.3. Discrete outcomes for class Keratolytic (topical) __________________________________________________________________________________________________________ 30etc1.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 19KB 5 pages Contents: Evidence Table C.1. Articles/arms for class Anti-bacterial (topical) __________________________________________________________________________________________________________ 31etc2.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 69KB 21 pages Contents: Evidence Table C.2. Continuous outcomes for class Anti-bacterial (topical) __________________________________________________________________________________________________________ 32etc3.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 30KB 7 pages Contents: Evidence Table C.3. Discrete outcomes for class Anti-bacterial (topical) __________________________________________________________________________________________________________ 33etd1.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 16KB 4 pages Contents: Evidence Table D.1. Articles/arms for class Anti-bacterial (topical)/Keratolytic (topical) __________________________________________________________________________________________________________ 34etd2.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 34KB 7 pages Contents: Evidence Table D.2. Continuous outcomes for class Anti-bacterial (topical)/Keratolytic (topical) __________________________________________________________________________________________________________ 35etd3.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 24KB 4 pages Contents: Evidence Table D.3. Discrete outcomes for class Anti-bacterial (topical)/Keratolytic (topical) __________________________________________________________________________________________________________ 36ete1.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 20KB 5 pages Contents: Evidence Table E.1. Articles/arms for class Retinoid (topical) __________________________________________________________________________________________________________ 37ete2.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 63KB 18 pages Contents: Evidence Table E.2. Continuous outcomes for class Retinoid (topical) __________________________________________________________________________________________________________ 38ete3.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 49KB 15 pages Contents: Evidence Table E.3. Discrete outcomes for class Retinoid (topical) __________________________________________________________________________________________________________ 39etg1.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 9KB 1 page Contents: Evidence Table G.1. Articles/arms for class Anti-bacterial/Retinoid (topical) G.2. Continuous outcomes for class Anti-bacterial/Retinoid (topical) __________________________________________________________________________________________________________ 40etg2.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 19KB 2 pages Contents: Evidence Table G.2. Continuous outcomes for class Anti-bacterial/Retinoid (topical) __________________________________________________________________________________________________________ 41eth1.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 27KB 7 pages Contents: Evidence Table Evidence Table H.1. Articles/arms for class Anti-bacterial (oral) __________________________________________________________________________________________________________ 42eth2.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 56KB 15 pages Contents: Evidence Table H.2. Continuous outcomes for class Anti-bacterial (oral) __________________________________________________________________________________________________________ 43eth3.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 50KB 14 pages Contents: Evidence Table H.3. Discrete outcomes for class Anti-bacterial (oral) __________________________________________________________________________________________________________ 44eti1.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 6KB 1 page Contents: Evidence Table I.1. Articles/arms for class Anti-bacterial (oral)/Keratolytic (topical) __________________________________________________________________________________________________________ 45eti2.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 17KB 2 pages Contents: Evidence Table I.2. Continuous outcomes for class Anti-bacterial (oral)/Keratolytic (topical) __________________________________________________________________________________________________________ 46etj1.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 6KB 1 page Contents: Evidence Table J.1. Articles/arms for class Anti-bacterial (oral)/Retinoid (topical) __________________________________________________________________________________________________________ 47etj2.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 16KB 2 pages Contents: Evidence Table J.2. Continuous outcomes for class Anti-bacterial (oral)/Retinoid (topical) __________________________________________________________________________________________________________ 48etj3.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 14KB 1 page Contents: Evidence Table J.3. Discrete outcomes for class Anti-bacterial (oral)/Retinoid (topical) __________________________________________________________________________________________________________ 49etk1.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 11KB 2 pages Contents: Evidence Table K.1. Articles/arms for class Retinoid (oral) __________________________________________________________________________________________________________ 50etk2.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 33KB 7 pages Contents: Evidence Table K.2. Continuous outcomes for class Retinoid (oral) __________________________________________________________________________________________________________ 51etk3.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 17KB 2 pages Contents: Evidence Table K.3. Discrete outcomes for class Retinoid (oral) __________________________________________________________________________________________________________ 52etm1.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 17KB 4 pages Contents: Evidence Table M.1. Articles/arms for class Anti-androgen __________________________________________________________________________________________________________ 53etm2.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 35KB 7 pages Contents: Evidence Table M.2. Continuous outcomes for class Anti-androgen __________________________________________________________________________________________________________ 54etm3.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 29KB 7 pages Contents: Evidence Table M.3. Discrete outcomes for class Anti-androgen __________________________________________________________________________________________________________ 55etn1.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 24KB 6 pages Contents: Evidence Table N.1. Articles/arms for class Other __________________________________________________________________________________________________________ 56etn2.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 41KB 10 pages Contents: Evidence Table N.2. Continuous outcomes for class Other __________________________________________________________________________________________________________ 57etn3.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 38KB 10 pages Contents: Evidence Table N.3. Discrete outcomes for class Other __________________________________________________________________________________________________________ 58etmul1.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 22KB 2 pages Contents: Evidence Table Multi.1. Trials with multi-arm outcomes __________________________________________________________________________________________________________ 59etmul2.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 146KB 10 pages Contents: Evidence Table Multi.2. Continuous outcomes of multi-arm trials __________________________________________________________________________________________________________ 60etmul3.pdf Adobe Acrobat® Document Adobe Acrobat® 3.02 117KB 11 pages Contents: Evidence Table Multi.3. Discrete outcomes of multi-arm trials __________________________________________________________________________________________________________ 61etabbr.wpd Corel WordPerfect® Document Corel WordPerfect® 6/7/8 8KB 1 page Contents: Selected Clinical Abbreviations Used in the Evidence Tables __________________________________________________________________________________________________________ 62biblio.wpd Corel WordPerfect® Document Corel WordPerfect® 6/7/8 121KB 32 pages Contents: Bibliography __________________________________________________________________________________________________________
AHRQ Publication No. 01-E019
Current as of September 2001
Internet Citation:
Management of Acne. File Inventory, Evidence Report/Technology Assessment Number 17. AHRQ Publication No. 01-E019, September 2001. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/clinic/acneinv.htm
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