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Blair R, Fang H, Branham WS, Hass B, Dial SL, Moland CL, Tong W, Shi L, Perkins R, Sheehan DM. Estrogen receptor relative binding affinities of 188 natural and xenochemicals: structural diversity of ligands. Toxicol. Sci. 54:138-153; 2000.
Branham WS, Dial SL, Moland CL, Hass B, Blair R, Fang H, Shi L, Tong W, Perkins R, Sheehan DM. Phytoestrogen and mycoestrogen binding to rat uterine estrogen receptor. American Journal of Nutrition; 2001 (accepted).
Fang H, Tong W, Perkins R, Soto A, Prechtl N, Sheehan DM. Quantitative comparison of in vitro assays for estrogenic activity. Environ. Health Perspect. 108(8): 723-729; 2000.
Fang H, Tong W, Shi L, Blair R, Perkins R, Branham WS, Dial SL, Moland CL, Sheehan DM. Structure - activity relationships for a large diverse set of natural, synthetic and environmental estrogens. Chem. Res. Toxicol. 14(3): 280-294, 2001.
Hong H, Tong W, Fang H, Shi L, Qian X, Wu J, Perkins R, Walker JD, Branham W, Sheehan D. Prediction of estrogen receptor binding for 58,000 chemicals using an integrated system of a tree-based model with structural alerts. Environ. Health Perspect. 2001 (in press).
Perkins RG, Anson JF, Blair RM, Branham WS, Chen Y, Dial SL, Fang H, Hass BS, Jackson MA, Lu M, Meehan JF, Moland CL, Nossaman RK, Shi LM, Tong W, Tu M, Welsh WJ, and Sheehan DM. The Estrogen Knowledge Base: A prototype toxicological knowledge base and predictive models for endocrine disrupting compounds, 2000, Walker JD, SETAC, Pensacola, FL.
Sheehan DM, Branham WS, Tong W, Perkins R. Phytoestrogens and synthetic chemicals as Developmental Endocrine Disruptors. Newsletter Japan 2:3; 1998.
Shi LM, Tong W, Fang H, Perkins R, Wu J, Tu M, Blair R, Branham W, Waller C, Walker J, Sheehan D. An integrated "Four-Phase" approach for priority setting of endocrine disruptors - Phase I and II for prediction of potential estrogenic endocrine disruptor. SAR/QSAR in Environ. Res. 2001 (in press).
Shi LM, Fang H, Tong W, Wu J, Perkins R, Blair R, Branham W, Sheehan D. QSAR models using a large diverse set of estrogens. J. Chem. Inf. Comp. Sci. 41(1): 186-195, 2001.
Tong W, Perkins R, Strelitz R, Collantes ER, Keenan S, Welsh WJ, Branham WS, Sheehan DM. Quantitative structure-activity relationships (QSARs) for estrogen binding to the estrogen receptor: predictions across species. Environ. Health Perspect. 105:1116-24; 1997.
Tong W, Perkins R, Xing L, Welsh WJ, Sheehan DM. QSAR models for binding of estrogenic compounds to estrogen receptor alpha and beta subtypes. Endocrin. 138:4022-5; 1997.
Tong W, Lowis DR, Perkins R, Chen Y, Welsh WJ, Goddette DW, Heritage TW, Sheehan DM. Evaluation of quantitative structure-activity relationship methods for large-scale prediction of chemicals binding to the estrogen receptor. J. Chem. Inf. Comput. Sci. 38:669-77; 1998.
Tong W, Perkins R, Wu J, Shi L, Tu M, Fang H, Blair R, Branham W, Sheehan DM. An integrated computational approach for prioritizing potential estrogens. Proceeding of the International Symposium on Environmental Endocrine Disruptors, Dec, Kobe, Japan, 1999.
Tong W, Perkins R, Sheehan DM. Perspectives on three-dimensional Quantitative Structure-Activity Relationship (3D-QSAR)/Comparative Molecular Field Analysis (CoMFA) in determining estrogenic effects. Japan Chemistry Today 2:50-57; 1999.
Xing L, Welsh WJ, Tong W, Perkins R, Sheehan DM. Comparison of estrogen receptor alpha and beta subtypes based on comparative molecular field analysis (CoMFA). SAR/QSAR Environ. Res. 10:215-237; 1999.
Fang H, Tong W, Sheehan DM. QSARs in receptor-mediated Effects: The nuclear receptor superfamily. Journal of Molecular Structure (THEOCHEM) (in preparation; invited review paper for special issue of "QSAR in Toxicology and Drug Design"), 2001
Perkins R, Fang H, Tong W, Welsh WJ. Quantitative structure-activity relationship (QSAR) methods: Perspective on drug discovery and toxicology Environmental Toxicology and Chemistry, 2001 (submitted).
Qian X, Tong W, Fang H, Hong H, Tu M, Perkins R, Blair R, Branham W, Sheehan D. Pharmacophore searching as a priority setting technique for screening and testing of endocrine disruptors. 2001 (in preparation).
Tong W, Welsh WJ, Shi L,
Fang H, Perkins R.SAR approaches and applications. Environmental Toxicology
and Chemistry, 2001 (submitted).
