Prepared by:
New England Medical Center Evidence-based Practice Center
Joseph Lau, M.D.
Principal Investigator
John P.A. Ioannidis, M.D.
Ethan Balk, M.D., M.P.H.
Catherine Milch, M.D.
Priscilla Chew, M.P.H.
Norma Terrin, Ph.D.
Thomas A. Lang, M.A.
Deeb Salem, M.D.
John B. Wong, M.D.
Investigators
File Name Description Software Version File Size __________________________________________________________________________________________________________ 01front.doc Microsoft Word® Document MS Word® 97 SR-1 38KB 6 pages Contents: Inside Front Cover, Title Page, Preface, Structured Abstract 02cont.doc Microsoft Word® Document MS Word® 97 SR-1 26KB 3 pages Contents: Table of Contents 03summ.doc Microsoft Word® Document MS Word® 97 SR-1 49KB 7 pages Contents: Summary: Introduction; Reporting the Evidence; Methods; Findings; Results of Decision and Cost-Effectiveness Analysis; Future Research 04chap1.doc Microsoft Word® Document MS Word® 97 SR-1 121KB 11 pages Contents: Chapter 1. Introduction: The 1997 NHAAP Report; The Charge To Update the 1997 Report; Issues in Diagnosing Acute Cardiac Ischemia in Emergency Departments; The Updated Evidence Report; Summary 05chap2.doc Microsoft Word® Document MS Word® 97 SR-1 86KB 12 pages Contents: Chapter 2. Methods: Aim of the Evidence Report; Literature Search; Study Selection; Data Abstraction; Reporting the Results; Supplemental Analyses (Meta-Analysis, Decision and Cost-Effectiveness Analysis) 06chap3.doc Microsoft Word® Document MS Word® 97 SR-1 471KB 68 pages Contents: Chapter 3. Results: Study Population Categories and Prevalence of AMI; Summary of Evidence for the Diagnostic Technologies 07chap4.doc Microsoft Word® Document MS Word® 97 SR-1 88KB 12 pages Contents: Chapter 4. Conclusions: General Observations on the Studies Analyzed; Observations on the Prevalence of Acute Cardiac Ischemia; Conclusions About the Diagnostic Technologies; Decision and Cost-Effectiveness Analysis 08chap5.doc Microsoft Word® Document MS Word® 97 SR-1 30KB 3 pages Contents: Chapter 5. Future Research: Diagnostic Performance Studies; Combinations of Diagnostic Technologies; Clinical Impact Studies; Multiple But Standardized Research Variables; Higher Quality Studies and Better Reporting 09refs.doc Microsoft Word® Document MS Word® 97 SR-1 72KB 9 pages Contents: References 10etabls.doc Microsoft Word® Document MS Word® 97 SR-1 554KB 111 pages Contents: Evidence Table 1a. Diagnostic performance studies evaluating prehospital 12-lead electrocardiography for the diagnoses of acute cardiac ischemia; Evidence Table 1b. Clinical impact of randomized studies involving prehospital diagnoses to manage acute cardiac ischemia; Evidence Table 1c. Clinical impact of nonrandomized studies involving prehospital diagnoses to manage acute cardiac ischemia; Evidence Table 2. Diagnostic performance studies evaluating continuous/serial electrocardiography for the diagnoses of acute cardiac ischemia in the emergency department; Evidence Table 3. Diagnostic performance evaluating nonstandard electrocardiography for the diagnoses of acute cardiac ischemia in the emergency department (all patients admitted); Evidence Table 4a. Diagnostic performance studies evaluating electrocardiographic exercise stress test for the diagnoses of acute cardiac ischemia in the emergency department; Evidence Table 4b. Clinical impact studies evaluating electrocardiographic exercise stress test to manage acute cardiac ischemia in the emergency department; Evidence Table 5a. Diagnostic performance studies evaluating presentation CK for AMI in the ED; Evidence Table 5b. Diagnostic performance studies evaluating presentation CK for AMI in the ED (other clinical studies); Evidence Table 6. Diagnostic performance studies evaluating serial CK for AMI in the ED; Evidence Table 7a. Diagnostic performance studies evaluating presentation CK-MB for AMI in the ED; Evidence Table 7b. Diagnostic performance studies evaluating presentation CK-MB for AMI in the ED (other clinical studies); Evidence Table 8a. Diagnostic performance studies evaluating serial CK-MB for AMI in the ED; Evidence Table 8b. Diagnostic performance studies evaluating serial CK-MB for AMI in the ED (other clinical trials); Evidence Table 9a. Diagnostic performance studies evaluating presentation troponin I for acute myocardial infarction in the emergency department; Evidence Table 9b. Diagnostic performance studies evaluating presentation troponin I for acute myocardial infarction in the emergency department (all patients admitted); Evidence Table 9c. Diagnostic performance studies evaluating serial troponin I for acute myocardial infarction in the emergency department; Evidence Table 9d. Diagnostic performance studies evaluating serial troponin I for acute myocardial infarction (patients admitted to CCU); Evidence Table 10a. Diagnostic performance studies evaluating presentation troponin T for acute myocardial infarction in the emergency department; Evidence Table 10b. Diagnostic performance studies evaluating presentation troponin T for acute myocardial infarction (other settings); Evidence Table 11a. Diagnostic performance studies evaluating serial troponin T for acute myocardial infarction in the emergency department; Evidence Table 11b. Diagnostic performance studies evaluating serial troponin T for acute myocardial infarction (other studies); Evidence Table 12. Diagnostic performance studies evaluating presentation myoglobin for AMI in the ED; Evidence Table 13a. Diagnostic performance studies evaluating serial myoglobin for AMI in the ED; Evidence Table 13b. Diagnostic performance studies evaluating serial myoglobin for AMI in the ED (other clinical trials); Evidence Table 14a. Diagnostic performance studies evaluating two-dimensional rest echocardiography for the diagnoses of acute cardiac ischemia in the emergency department; Evidence Table 14b. Diagnostic performance studies evaluating two-dimensional stress echocardiography for the diagnoses of acute cardiac ischemia in the emergency department; Evidence Table 15. Diagnostic performance studies evaluating technetium-99m sestamibi for the diagnoses of acute cardiac ischemia in the emergency department; Evidence Table 16a. Diagnostic performance studies evaluating ACI predictive instrument and ACI time-insensitive predictive instrument for the diagnoses of acute cardiac ischemia in the emergency department; Evidence Table 16b. Clinical impact studies evaluating ACI predictive instrument and ACI time-insensitive predictive instrument to manage acute cardiac ischemia in the emergency department; Evidence Table 17a. Diagnostic performance studies evaluating Goldman predictive instrument for the diagnoses of acute cardiac ischemia in the emergency department; Evidence Table 17b. Clinical impact studies evaluating Goldman predictive instrument to manage acute cardiac ischemia in the emergency department; Evidence Table 18a. Diagnostic performance studies evaluating algorithm protocols for the diagnoses of acute cardiac ischemia in the emergency department; Evidence Table 18b. Clinical impact studies evaluating algorithm protocols to manage acute cardiac ischemia in the emergency department; Evidence Table 19a. Diagnostic performance studies evaluating computer-based decision aids for the diagnoses of acute cardiac ischemia in the emergency department; Evidence Table 19b. Clinical impact studies evaluating computer-based decision aids to manage acute cardiac ischemia in the emergency department 11meta.doc Microsoft Word® Document MS Word® 97 SR-1 209KB 23 pages Contents: Supplemental Analyses: Meta-Analyses 12deccst.doc Microsoft Word® Document MS Word® 97 SR-1 966KB 32 pages Contents: Supplemental Analyses: Decision and Cost-Effectiveness Analysis 13biblio.doc Microsoft Word® Document MS Word® 97 SR-1 76KB 10 pages Contents: Bibliography 14appa-1.doc Microsoft Word® Document MS Word® 97 SR-1 27KB 2 pages Contents: Appendix A. Data Abstraction Forms: DIAGNOSTIC TESTS FOR ACI IN THE EMERGENCY DEPARTMENT INITIAL ARTICLE SCREEN FORM 15appa-2.doc Microsoft Word® Document MS Word® 97 SR-1 40KB 3 pages Contents: Appendix A. Data Abstraction Forms: DIAGNOSTIC TESTS FOR ACI IN THE EMERGENCY DEPARTMENT 16appa-3.doc Microsoft Word® Document MS Word® 97 SR-1 30KB 2 pages Contents: Appendix A. Data Abstraction Forms: Quality Assessment of Evaluations of Diagnostic Test Performance for ACI/AMI 17appb.doc Microsoft Word® Document MS Word® 97 SR-1 23KB 2 pages Contents: Appendix B. Acknowledgments 18appc.doc Microsoft Word® Document MS Word® 97 SR-1 21KB 1 page Contents: Appendix C. Acronyms __________________________________________________________________________________________________________
AHRQ Publication No. 01-E006
Current as of May 2001
Internet Citation:
Evaluation of Technologies for Identifying Acute Cardiac Ischemia in Emergency Departments. File Inventory, Evidence Report/Technology Assessment Number 26. AHRQ Publication No. 01-E006, May 2001. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/clinic/aciscinv.htm
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