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Human/Mouse Homology Relationships |
| PubMed | Entrez | BLAST | OMIM | Taxonomy | Structure |
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Michael F. Seldin, Rowe Program in Genetics, Departments of Biological Chemistry and Medicine, University of California, Davis.
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This is the Davis Human/Mouse Homology Map, a table comparing genes
in homologous segments of DNA from human and mouse sources, sorted by
position in each genome. A total of 1793 loci are presented, most of which are
genes. The authors did not include pseudogenes, members of multigene families
where specific homology relationships could not be determined, nor any other
genes for which homology was in doubt. In addition, for 568 of the loci
there are provisional assignments of markers that link the homology map with
that of the
Gene Map of the Human Genome. These links also provide a rough
approximation of the position of markers in the Genethon linkage map.
In constructing this table, the authors first ordered genes so as to best
maintain
order according to both human cytogenetic position and mouse genetic map
position. Within these homologous regions, genes were ordered according to the
mouse genetic mapping data. For approximately half of the genes in this
database, no more detailed information is available; thus, much of this map
should be interpreted as a
reflection of probable, not confirmed, homology relationships. Where more
detailed information was to be found, the authors adjusted the map to
correspond to available human physical mapping data, which they consider to be
definitive. The present rendition contains 201 homology groupings.
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Description