Clinical Trial: Evaluating Pancreatic Tumors in Patients with Zollinger-Ellison Syndrome


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Evaluating Pancreatic Tumors in Patients with Zollinger-Ellison Syndrome

This study is currently recruiting patients.

Sponsored by:	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Information provided by:	Warren G Magnuson Clinical Center (CC)

Purpose

This protocol concerns the approach to the localization, diagnosis of MEN1 and management of the tumor and the tissue samples in patients with Zollinger-Ellison syndrome. It details the diagnostic imaging tests to be used to localize the tumor, investigations for MEN1 the subsequent management of the tumor and tissue samples for research.

Condition
Gastrinoma Zollinger Ellison Syndrome

Study Type: Observational
Study Design: Natural History

Official Title: Evaluation of the Gastrinoma in Patients with Zollinger-Ellison Syndrome

Further Study Details:

Expected Total Enrollment: 999

Study start: May 22, 1990

This protocol concerns the approach to tumor localization, diagnosis of MEN1 and management of the tumor and the tissue samples in patients with Zollinger-Ellison syndrome. It details the diagnostic imaging tests to be used to localize the tumor, investigations for MEN1 the subsequent management of the tumor and tissue samples for research.

Eligibility

Genders Eligible for Study: Both

Criteria

INCLUSION CRITERIA:
New patients will be evaluated initially as described in the protocol entitled, "Diagnostic evaluation of patients with suspected abnormalities of gastric secretion" (89-DK-0005).
Only those patients that are being treated under the protocol entitled, "Medical Therapy of Zollinger-Ellison Syndrome" (protocol # 89-DK-0015) will be entered into this tumor localization and management protocol.

Location and Contact Information

Maryland
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), 9000 Rockville Pike, Bethesda, Maryland, 20892, United States; Recruiting

Patient Recruitment and Public Liaison Office 1-800-411-1222 prpl@mail.cc.nih.gov
TTY 1-866-411-1010

More Information

Detailed Web Page

Publications

Wolfe MM, Jensen RT. Zollinger-Ellison syndrome. Current concepts in diagnosis and management. N Engl J Med. 1987 Nov 5;317(19):1200-9. Review.

Andersen DK. Current diagnosis and management of Zollinger-Ellison syndrome. Ann Surg. 1989 Dec;210(6):685-703. Review.

Creutzfeldt W, Arnold R, Creutzfeldt C, Track NS. Pathomorphologic, biochemical, and diagnostic aspects of gastrinomas (Zollinger-Ellison syndrome). Hum Pathol. 1975 Jan;6(1):47-76.

Study ID Numbers: 900137; 90-DK-0137
Record last reviewed: April 14, 2004
Last Updated: April 14, 2004
Record first received: November 3, 1999
ClinicalTrials.gov Identifier: NCT00001254
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2004-11-08

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National Institutes of Health, Department of Health & Human Services