Prepared by:
Minnesota Evidence-based Practice Center, Minneapolis, Minnesota
Investigators
Robert L. Kane, M.D.
Khaled J. Saleh, M.D., M.Sc., FRCSC
Timothy J. Wilt, M.D., M.P.H.
Boris Bershadsky, Ph.D.
William W. Cross III, B.A.
Roderick M. MacDonald, M.S.
Indulis Rutks, B.S.
File Name Description Software Version File Size ________________________________________________________________________________________________ 01titlpg.doc Microsoft Word® Document MS Word® 2002 27KB 2 pages Contents: Title Page ________________________________________________________________________________________________ 02pref.doc Microsoft Word® Document MS Word® 2002 25KB 2 pages Contents: Preface ________________________________________________________________________________________________ 03ackn.doc Microsoft Word® Document MS Word® 2002 20KB 1 page Contents: Acknowledgments ________________________________________________________________________________________________ 04abstr.doc Microsoft Word® Document MS Word® 2002 31KB 2 pages Contents: Structured Abstract ________________________________________________________________________________________________ 05conts.doc Microsoft Word® Document MS Word® 2002 36KB 4 pages Contents: Table of Contents ________________________________________________________________________________________________ 06chap1.doc Microsoft Word® Document MS Word® 2002 35KB 5 pages Contents: Chapter 1. Introduction ________________________________________________________________________________________________ 07tbl1.doc Microsoft Word® Document MS Word® 2002 56KB 4 pages Contents: Table 1. Studies of beliefs about indications, referrals, and thresholds for total knee arthroplasty ________________________________________________________________________________________________ 08tbl2.doc Microsoft Word® Document MS Word® 2002 39KB 3 pages Contents: Table 2. Summary of studies of clinical agreement about patient factors for either referral or surgery ________________________________________________________________________________________________ 09chap2.doc Microsoft Word® Document MS Word® 2002 34KB 4 pages Contents: Chapter 2. Methods and Analytic Framework: TKA Indicators, TKA Access, TKA Revisions ________________________________________________________________________________________________ 10fig1.doc Microsoft Word® Document MS Word® 2002 27KB 2 pages Contents: Figure 1. TKA article inclusion/exclusion flow chart ________________________________________________________________________________________________ 11chap3.doc Microsoft Word® Document MS Word® 2002 62KB 10 pages Contents: Chapter 3. Results: Baseline Characteristics of Patients; What is the Magnitude of Effect of Primary TKA?; Revisions and Complications; What are the Correlates of Functional Outcomes?; Does Access to TKA Vary with Race and Gender?; Total Knee Arthroplasty Revisions (TKAR) ________________________________________________________________________________________________ 12tbl3.doc Microsoft Word® Document MS Word® 2002 38KB 1 page Contents: Table 3. Descriptive statistics on 62 studies ________________________________________________________________________________________________ 13tbl4.doc Microsoft Word® Document MS Word® 2002 32KB 1 page Contents: Table 4. Mean followup duration according to functional assessment scale ________________________________________________________________________________________________ 14tbl5.doc Microsoft Word® Document MS Word® 2002 30KB 1 page Contents: Table 5. Weighted baseline and followup scores for TKA outcomes measures ________________________________________________________________________________________________ 15tbl6.doc Microsoft Word® Document MS Word® 2002 490KB 7 pages Contents: Table 6. Functional outcomes by measure and followup interval based on number of subjects ________________________________________________________________________________________________ 16tbl7.doc Microsoft Word® Document MS Word® 2002 317KB 5 pages Contents: Table 7. Functional outcomes by measure and followup interval based on number of knees ________________________________________________________________________________________________ 17tbl8.doc Microsoft Word® Document MS Word® 2002 84KB 1 page Contents: Table 8. Meta analysis for HSS ________________________________________________________________________________________________ 18tbl9.doc Microsoft Word® Document MS Word® 2002 157KB 2 pages Contents: Table 9. Meta analysis for KS ________________________________________________________________________________________________ 19tbl10.doc Microsoft Word® Document MS Word® 2002 56KB 1 page Contents: Table 10. Meta analysis for WOMAC ________________________________________________________________________________________________ 20tbl11.doc Microsoft Word® Document MS Word® 2002 46KB 1 page Contents: Table 11. Meta analysis for SF-36 ________________________________________________________________________________________________ 21tbl12.doc Microsoft Word® Document MS Word® 2002 29KB 1 page Contents: Table 12. Revision rates after primary TKAs ________________________________________________________________________________________________ 22tbl13.doc Microsoft Word® Document MS Word® 2002 119KB 7 pages Contents: Table 13. Assessmentg of TKA prostheses and surgical procedures ________________________________________________________________________________________________ 23tbl14.doc Microsoft Word® Document MS Word® 2002 35KB 2 pages Contents: Table 14. Asessment of TKA procedures/programs ________________________________________________________________________________________________ 24tbl15.doc Microsoft Word® Document MS Word® 2002 41KB 2 pages Contents: Table 15. Complications: Prevention of Venous Thrombosis (VT)/Pulmonary Embolism (PE) studies ________________________________________________________________________________________________ 25tbl16.doc Microsoft Word® Document MS Word® 2002 31KB 1 page Contents: Table 16. Complications: Prevention of infection studies ________________________________________________________________________________________________ 26tbl17.doc Microsoft Word® Document MS Word® 2002 28KB 1 page Contents: Table 17. Complications: Tourniquet studies ________________________________________________________________________________________________ 27tbl18.doc Microsoft Word® Document MS Word® 2002 27KB 1 page Contents: Table 18. Number of studies that include potential correlates of function ________________________________________________________________________________________________ 28tbl19.doc Microsoft Word® Document MS Word® 2002 72KB 1 page Contents: Table 19. TKA outcomes scores based on age, gender, BMI-index/obesity, and type of arthritis ________________________________________________________________________________________________ 29tbl20.doc Microsoft Word® Document MS Word® 2002 56KB 2 pages Contents: Table 20. TKAR studies using multiple regression modeling ________________________________________________________________________________________________ 30tbl21.doc Microsoft Word® Document MS Word® 2002 37KB 2 pages Contents: Table 21. Gender/racial disparities in total knee arthroplasty studies ________________________________________________________________________________________________ 31tbl22.doc Microsoft Word® Document MS Word® 2002 30KB 1 page Contents: Table 22. Summary of race and gender effects on TKA rates ________________________________________________________________________________________________ 32tbl23.doc Microsoft Word® Document MS Word® 2002 61KB 4 pages Contents: Table 23. Updates on total knee revision studies ________________________________________________________________________________________________ 33fig2-4.doc Microsoft Word® Document MS Word® 2002 856KB 3 pages Contents: Figure 2. Mean increase in Knee Society scores (postoperative less preoperative scores) as a function of postoperative followup (months) for subjects undergoing TKA revision surgery; Figure 3. Mean increase in Hospital Special Surgery scores (postoperative less preoperative scores) as a function of postoperative followup (months) for subjects undergoing TKA revision surgery; Figure 4. Proportion of subjects undergoing TKA revision surgery in each cohort self-rated as excellent or good as a function of postoperative followup (months) ________________________________________________________________________________________________ 34chap4.doc Microsoft Word® Document MS Word® 2002 44KB 6 pages Contents: Chapter 4. Discussion: Research Recommendations, Research Agenda ________________________________________________________________________________________________ 35tbl24.doc Microsoft Word® Document MS Word® 2002 40KB 2 pages Contents: Table 24. Potential study questions ________________________________________________________________________________________________ 36refs.doc Microsoft Word® Document MS Word® 2002 75KB 6 pages Contents: References and Included Studies ________________________________________________________________________________________________ 37exclst.doc Microsoft Word® Document MS Word® 2002 323KB 26 pages Contents: Listing of Excluded Studies ________________________________________________________________________________________________ 38acros.doc Microsoft Word® Document MS Word® 2002 46KB 2 pages Contents: List of Acronyms/Abbreviations ________________________________________________________________________________________________ 39appa.doc Microsoft Word® Document MS Word® 2002 207KB 14 pages Contents: Appendix A. Measurement Scales: Hospital for Special Surgery score (HSS); Knee Society (KS) score; Western Ontario and MacMaster University (WOMAC) Osteoarthritis Index ________________________________________________________________________________________________ 40appb.doc Microsoft Word® Document MS Word® 2002 36KB 4 pages Contents: Appendix B. Technical Expert Panel Members and Reviewers ________________________________________________________________________________________________ 41appc.doc Microsoft Word® Document MS Word® 2002 30KB 6 pages Contents: Appendix C. Exact Search Strings: Search Strings for Total Knee Arthroplasty (TKA) Scores; Search Strings for Total Knee Arthroplasty Access; Search Strings for Total Knee Arthroplasty Revisions ________________________________________________________________________________________________ 42appd.doc Microsoft Word® Document MS Word® 2002 263KB 18 pages Contents: Appendix D. Abstracting Form ________________________________________________________________________________________________ 43appe.doc Microsoft Word® Document MS Word® 2002 1.2MB 24 pages Contents: Appendix E. Functional Outcome Following Total Knee Arthroplasty Revision: A Meta Analysis (Saleh et al.) ________________________________________________________________________________________________ 44evtbl1.doc Microsoft Word® Document MS Word® 2002 172KB 10 pages Contents: Evidence Table 1. Primary TKA studies with at least a pre/post design ________________________________________________________________________________________________ 45evtbl2.doc Microsoft Word® Document MS Word® 2002 153KB 4 pages Contents: Evidence Table 2. Basic information for calculating revision rates ________________________________________________________________________________________________ 46evtbl3.doc Microsoft Word® Document MS Word® 2002 130KB 4 pages Contents: Evidence Table 3. Basic information for calculating complication rates ________________________________________________________________________________________________
AHRQ Publication No. 04-E006-2
Current as of December 2003
Internet Citation:
Total Knee Replacement. File Inventory, Evidence Report/Technology Assessment Number 86. AHRQ Publication No. 04-E006-2, December 2003. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/clinic/kneeinv.htm
Return to Evidence-based Practice
Clinical Information
AHRQ Home Page
Department of Health and Human Services