Accessible Version

Science for the Brain
The nation's leading supporter of biomedical research on disorders of the brain and nervous system

Browse all disorders

Browse all health
   organizations

More about
Tourette Syndrome
Studies with patients
Research literature
Press releases

Disclaimer

(help)
Contact us
My privacy

NINDS is part of the
National Institutes of
Health

  NINDS Tourette Syndrome Information Page
  
Reviewed  07-01-2001  

Get Web page suited for printing
Email this to a friend or colleague

Table of Contents (click to jump to sections)

What is Tourette Syndrome?
Is there any treatment?
What is the prognosis?
What research is being done?

Organizations
Related NINDS Publications and Information
Additional resources from MEDLINEplus

What is Tourette Syndrome?
Tourette Syndrome (TS) is an inherited neurological disorder characterized by repeated involuntary movements and uncontrollable vocal sounds called tics. In a few cases, such tics can include inappropriate words and phrases. The symptoms of TS generally appear before the individual is 18 years old. Although TS symptoms range from very mild to quite severe, the majority of cases fall into the mild category. The first symptoms of TS are usually facial tics - commonly eye blinking. With time, other motor tics may appear, such as head jerking, neck stretching, foot stamping, or body twisting and bending. It is not uncommon for a person with TS to continuously clear his or her throat, cough, sniff, grunt, yelp, bark, or shout. A person with TS may touch other people excessively or repeat actions obsessively and unnecessarily. A few patients with TS demonstrate self-harming behaviors such as lip and cheek biting and head banging. People with TS can sometimes suppress their tics for a short time, but eventually tension mounts to the point where the tic escapes. Tics worsen in stressful situations and improve when the person relaxes or is absorbed in an activity. TS is diagnosed by observing the symptoms and evaluating family history. Tics must be present for at least one year. TS is a clinical diagnosis.

Is there any treatment?
The majority of people with TS require no medication, but medication is available to help when symptoms interfere with functioning. TS medications are only able to help reduce specific symptoms. Neuroleptic and antihypertensive drugs can have long- and short-term side effects, and use of stimulants is controversial. Relaxation techniques and biofeedback may be useful in alleviating stress.

What is the prognosis?
There is no cure for TS; however, the condition in many individuals improves as they mature. Individuals with TS can expect to live a normal life span. Although TS is generally lifelong and chronic, it is not degenerative. In a few cases, complete remission occurs after adolescence.

What research is being done?
Investigators are conducting genetic linkage studies in large multigenerational families affected with TS in an effort to find the chromosomal location of the TS gene(s). Understanding the genetics of TS will directly benefit patients who are concerned about recurrence in their families and will ultimately help to clarify the development of the disorder. Investigators also are studying certain neurotransmitters to explore the role they play in the disease process and develop more effective therapies. Others are researching how environmental factors may influence the expression of the disease.

Select this link to view a list of all studies currently seeking patients.

 Organizations

Tourette Syndrome Association
42-40 Bell Boulevard
Suite 205
Bayside, NY 11361-2820
ts@tsa-usa.org
http://tsa-usa.org
Tel: 718-224-2999 888-4-TOURET (486-8738)
Fax: 718-279-9596

National Institute of Mental Health (NIMH)
National Institutes of Health, DHHS
6001 Executive Blvd. Rm. 8184, MSC 9663
Bethesda, MD 20892-9663
nimhinfo@nih.gov
http://www.nimh.nih.gov
Tel: 301-443-4513/301-443-8431 (TTY) 866-615-NIMH (-6464)
Fax: 301-443-4279

National Institute on Deafness and Other Communication Disorders (NIDCD)
National Institutes of Health, DHHS
31 Center Drive, Rm. 3C35 MSC 2320
Bethesda, MD 20892-2320
nidcdinfo@nidcd.nih.gov
http://www.nidcd.nih.gov
Tel: 301-496-7243 301-241-1055 (TTD/TTY)

Related NINDS Publications and Information

  • Tourette Syndrome Fact Sheet

  • Tourette Syndrome fact sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS)

  • Síndrome de Tourette

  • Informacion de Sindrome de Tourette/Spanish-language fact sheet on Tourette Syndrome compiled by the National Institute of Neurological Disorders and Stroke (NINDS).

  • NINDS Seeks Patients with Tourette Syndrome

  • Lay-language descriptions of new NINDS program announcements, requests for applications, and clinical studies seeking patients.

  • Methylphenidate and Clonidine Help Children With ADHD and Tics

  • April 2002 news summary on a clinical trial of methylphenidate and clonidine in children with ADHD and tics.


    NINDS health-related material is provided for information purposes only and does not necessarily represent endorsement by or an official position of the National Institute of Neurological Disorders and Stroke or any other Federal agency. Advice on the treatment or care of an individual patient should be obtained through consultation with a physician who has examined that patient or is familiar with that patient's medical history.

    All NINDS-prepared information is in the public domain and may be freely copied. Credit to the NINDS or the NIH is appreciated.


    Provided by:
    The National Institute of Neurological Disorders and Stroke
    National Institutes of Health
    Bethesda, MD 20892




    Return to top






    National Institute of Neurological Disorders and Stroke
    Home | About NINDS | Disorders | Funding | News & Events | Find People | Jobs & Training | Accessibility
    H H S Logo - link to U. S. Department of Health and Human Services     N I H logo - link to U. S. National Institutes of Health    N I N D S logo - link to National Institute of Neurological Disorders and Stroke    FirstGov Logo - link To FirstGov