Synonym(s): Tic Douloureux
Reviewed 05-29-2001 Get Web page suited for printing
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Table of Contents (click to jump to sections)
What is Trigeminal Neuralgia?
Is there any treatment?
What is the prognosis?
What research is being done?
Organizations
Related NINDS Publications and Information
What is Trigeminal Neuralgia?
Trigeminal neuralgia, also called tic douloureux, is a condition that affects the trigeminal nerve (the 5th cranial nerve), one of the largest nerves in the head. The trigeminal nerve is responsible for sending impulses of touch, pain, pressure, and temperature to the brain from the face, jaw, gums, forehead, and around the eyes. Trigeminal neuralgia is characterized by a sudden, severe, electric shock-like or stabbing pain typically felt on one side of the jaw or cheek. The disorder is more common in women than in men and rarely affects anyone younger than 50. The attacks of pain, which generally last several seconds and may be repeated one after the other, may be triggered by talking, brushing teeth, touching the face, chewing, or swallowing. The attacks may come and go throughout the day and last for days, weeks, or months at a time, and then disappear for months or years.Is there any treatment?
Treatment for trigeminal neuralgia typically includes anticonvulsant medications such as carbamazepine or phenytoin. Baclofen, clonazepam, gabapentin, and valproic acid may also be effective and may be used in combination to achieve pain relief. If medication fails to relieve pain, surgical treatment may be recommended.
What is the prognosis?
The disorder is characterized by recurrences and remissions, and successive recurrences may incapacitate the patient. Due to the intensity of the pain, even the fear of an impending attack may prevent activity. Trigeminal neuralgia is not fatal.
What research is being done?
Within the NINDS research programs, trigeminal neuralgia is addressed primarily through studies associated with pain research. NINDS vigorously pursues a research program seeking new treatments for pain and nerve damage with the ultimate goal of reversing debilitating conditions such as trigeminal neuralgia. NINDS has notified research investigators that it is seeking grant applications both in basic and clinical pain research.
Select this link to view a list of all studies currently seeking patients.
OrganizationsAmerican Chronic Pain Association (ACPA)
P.O. Box 850
Rocklin, CA
95677-0850
ACPA@pacbell.net
http://www.theacpa.org
Tel: 916-632-0922
800-533-3231
Fax: 916-632-3208
National Chronic Pain Outreach Association
(NCPOA)
P.O. Box 274
Millboro, VA
24460
ncpoa@cfw.com
http://www.chronicpain.org
Tel: 540-862-9437
Fax: 540-862-9485
Trigeminal Neuralgia Association
2801 SW Archer Road
Suite C
Gainesville, FL
32608
tnanational@tna-support.org
http://www.tna-support.org
Tel: 352-376-9955
Fax: 352-376-8688
National Foundation for the Treatment of Pain
P.O. Box 70045
Houston, TX
77270
markgordon@paincare.org
http://www.paincare.org
Tel: 713-862-9332
Fax: 713-862-9346
International Radiosurgery Support Association (IRSA)
P.O. Box 5186
Harrisburg, PA
17110
getinfo@irsa.org
http://www.irsa.org
Tel: 717-260-9808
Fax: 717-260-9809
Mayday Fund [For Pain Research]
c/o SPG
136 West 21st Street, 6th Floor
New York, NY
10011
mayday@maydayfund.org
http://www.painandhealth.org
Tel: 212-366-6970
Fax: 212-366-6979
Related NINDS Publications and InformationChronic Pain: Hope Through Research
Information booklet on pain compiled by the National Institute of Neurological Disorders and Stroke (NINDS).
Headache: Hope Through Research
Information booklet about headaches, including migraines.
Trigeminal Neuralgia: Opportunities for Research and Treatment
Summary of a workshop, "Trigeminal Neuralgia: Opportunities for Research and Treatment," September 1999.
NINDS health-related material is provided for information purposes only and does not necessarily represent endorsement by or an official position of the National Institute of Neurological Disorders and Stroke or any other Federal agency. Advice on the treatment or care of an individual patient should be obtained through consultation with a physician who has examined that patient or is familiar with that patient's medical history.
All NINDS-prepared information is in the public domain and may be freely copied. Credit to the NINDS or the NIH is appreciated.
Provided by:
The National Institute of Neurological Disorders and Stroke
National Institutes of Health
Bethesda, MD 20892
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