Placebo Controlled Study Evaluating the Effectiveness of Medication in Elderly Subjects with Major Depressive Disorder (MDD)

Condition	Treatment or Intervention	Phase
Major Depressive Disorder	Drug: Investigational Major Depression Disorder drug	Phase III

Ages Eligible for Study:  65 Years and above,  Genders Eligible for Study:  Both

Criteria

Inclusion Criteria:

• Primary diagnosis of Major Depressive Disorder with DSM-IV criteria for their current episode for at least 8 weeks.

Exclusion Criteria:

• Patient has current or past history of seizure disorder or brain injury.
• Patient has a diagnosis of anorexia or bulimia within the past 12 months.
• Patient has a past or current DMS-IV diagnosis of schizophrenia or any other psychotic disorder(s).
• Patient has had a myocardial infarction within 1 year or a history of uncontrolled hypertension or unstable heart disease with 6 months.

California
      Oceanside,  California,  92056,  United States; Recruiting
      Temecula,  California,  92591,  United States; Recruiting
Connecticut
      Norwich,  Connecticut,  06360,  United States; Recruiting
Florida
      Miami,  Florida,  33125,  United States; Recruiting
      Miami,  Florida,  33125,  United States; Recruiting
      Ocala,  Florida,  34474,  United States; Terminated
Louisiana
      Shreveport,  Louisiana,  71101,  United States; Recruiting
Maryland
      Rockville,  Maryland,  20852,  United States; Terminated
New York
      New York,  New York,  10021,  United States; Recruiting
Pennsylvania
      Philadelphia,  Pennsylvania,  19149,  United States; Recruiting
Tennessee
      Memphis,  Tennessee,  38119,  United States; Recruiting
Texas
      Richardson,  Texas,  75080,  United States; Recruiting

Study ID Numbers:  AK130940
Record last reviewed:  October 2004
Record first received:  October 5, 2004
ClinicalTrials.gov Identifier:  NCT00093288
Health Authority: United States: Food and Drug Administration
ClinicalTrials.gov processed this record on 2004-11-10