The purpose of this research study is to determine the efficacy and safety of fondaparinux (Arixtra) in preventing death and repeat heart attacks and their complications.

Condition	Treatment or Intervention	Phase
Myocardial Infarction	Drug: fondaparinux sodium  Drug: heparin  Drug: Glucose-insulin-potassium (GIK)	Phase III

Ages Eligible for Study:  21 Years and above,  Genders Eligible for Study:  Both

Criteria

Inclusion Criteria:

• Patients presenting or admitted to hospital with: a) signs and symptoms of acute myocardial infarction (AMI) b) able to randomize within 24 hours from symptom onset, and c) definite ECG changes indicating STEMI: persistant ST-elevation (greater than or equal to 0.2 mV in two contiguous precordial leads, or greater than or equal to 0.1 mV in at least two limb leads), or new left bundle branch block, or ECG changes indicating true posterior MI
• written informed consent

Exclusion criteria:

• age < 21 years
• currently receiving an oral anticoagulant agent with an INR > 1.8
• any contraindication to anticoagulation therapy such as high risk of bleeding or active bleeding
• hemorrhagic stroke within the last 12 months
• indication for anticoagulation other than acute coronary syndrome (ACS)
• pregnant women or women of child-bearing potential who are not using an effective method of contraception
• co-morbid condition with a life expectancy < 6 months
• prior enrolment in one of the fondaparinux ACS trials
• participation in another pharmacotherapeutic study within the prior 30 days or currently receiving an experitmental pharmacological agent
• known allergy to heparin or fondaparinux

Himanshu V Kothari, Ph.D.      973-325-5316    h.kothari@organonusa.com

Florida
      Brevard Cardiology Physicians, PA, Merritt Island,  Florida,  32953,  United States; Recruiting
      Wuesthoff Hospital, Rockledge,  Florida,  32955,  United States; Recruiting
      Ocala Research Institute, Inc., Ocala,  Florida,  United States; Recruiting
      Ocala Regional Medical Center, Ocala,  Florida,  United States; Recruiting
Illinois
      The University of Chicago Center for Advanced Medicine, Chicago,  Illinois,  United States; Recruiting
Maine
      St. Mary's Regional Medical Center, Lewiston,  Maine,  04243,  United States; Recruiting
New York
      Crouse Hospital, Syracuse,  New York,  13210,  United States; Recruiting
      Cardiology Associates, P.C., Johnson City,  New York,  United States; Recruiting
      Wilson Regional Medical Center of UHSH, Inc., Johnson City,  New York,  United States; Recruiting
Texas
      Northwest Texas Healthcare System, Amarillo,  Texas,  United States; Recruiting
      Amarillo Heart Group, Amarillo,  Texas,  United States; Recruiting
      Wilford Hall Medical Center, San Antonio,  Texas,  United States; Recruiting
Argentina
      Clinica Coronel Suarez, Buenos Aires,  Argentina; Recruiting
      Policlinica Bancaria, Buenos Aires,  Argentina; Recruiting
      Hospital "Luis Carlos Lagomaggiore", Mendoza,  Argentina; Recruiting
      Instituto de Cardiologia S.R.L., San Miguel de Tucuman,  Argentina; Recruiting
      Sanatorio Medico de Diagnostico y Tratamiento, Santa Fe,  Argentina; Recruiting
      Centro Privado de Cardiologia, San Miguel de Tucuman,  Argentina; Recruiting
      Hospital Centro de Salud, San Miguel de Tucuman,  Argentina; Recruiting
      Hospital San Bernardo, Salta,  Argentina; Recruiting
      Clinica Pivada Milenio S.A., Buenos Aires,  Argentina; Recruiting
      Corporacion Medica de General San Martin S.A., Buenos Aires,  Argentina; Recruiting
      Instituto Cardiovascular de Rosario, Santa Fe,  Argentina; Recruiting
      Hospital General de Agudos "Donacion Francisco Santojanni", Buenos Aires,  Argentina; Recruiting
      Antartida Instituto Medico, Buenos Aires,  Argentina; Recruiting
      Sanatorio Modelo Quilmes, Buenos Aires,  Argentina; Recruiting
      Clinica Privada Provincial S.A., Buenos Aires,  Argentina; Recruiting
      Clinica Modelo de Moron, Buenos Aires,  Argentina; Recruiting
      Hospital Italiano de La Plata, Buenos Aires,  Argentina; Recruiting
      Instituto Cardiovascular San Luis, San Luis,  Argentina; Recruiting
      Hospital Privado Centro Medico de Cordoba S.A., Cordoba,  Argentina; Recruiting
      Sanatorio Allende, Cordoba,  Argentina; Recruiting
      Clinica Privada Caraffe, Cordoba,  Argentina; Recruiting
      Hospital Frances, Buenos Aires,  Argentina; Recruiting
      Hospital Britanico de Buenos Aires, Buenos Aires,  Argentina; Recruiting
      Centro de Educacion Medica e Investigaciones Clinica "Norberto Quirno", Buenos Aires,  Argentina; Recruiting
Australia
      Royal North Shore Hospital, St. Leonards,  Australia; Recruiting
      Mackay Base Hospital, Mackay,  Australia; Recruiting
      Lismore Base Hospital, Lismore,  Australia; Recruiting
Australia, New South Wales
      Coffs Harbour Health Campus, Coffs Harbour,  New South Wales,  2450,  Australia; Recruiting
Australia, Victoria
      Central Gippsland Health Service, Sale,  Victoria,  3850,  Australia; Recruiting
      Austin Health, Heidelberg,  Victoria,  3084,  Australia; Recruiting
      Box Hill Hospital, Box Hill,  Victoria,  3128,  Australia; Recruiting
      Bendigo Hospital, Bendigo,  Victoria,  3550,  Australia; Recruiting
Australia, Western Australia
      Heart Research Institute - Sir Charles Gairdner Hospital, Nedlands,  Western Australia,  6009,  Australia; Recruiting
Austria
      Wilhelminen Hospital (Cardiology and Emergency Medicine), Vienna,  1160,  Austria; Recruiting
Belgium
      Algemeen Ziekenhuis Middelheim, Antwerpen,  2020,  Belgium; Recruiting
      Centre Hospitalier Regional Hutois, Huy,  4500,  Belgium; Recruiting
      Cliniques Universitaires Saint-Luc, BRUXELLES,  1200,  Belgium; Recruiting
      Algemeen Ziekenhuis Sint Jan, Brugge,  8000,  Belgium; Recruiting
      Sint Augustinuskliniek, Veurne,  8630,  Belgium; Recruiting
      Academic Hospital VUB, Brussels,  Belgium; Recruiting
Brazil
      Hospital Universitario Edgar Santos, Salvador,  Brazil; Recruiting
      Hospital Portugues, Salvador,  Brazil; Recruiting
      Instituto Nacional de Cardiologia Laranjeiras, Rio de Janeiro,  Brazil; Recruiting
      Instituto do Coracao, Sao Paulo,  Brazil; Recruiting
      Hospital Santa Rita, Maringa,  Brazil; Recruiting
      Santa Casa de Belo Horizonte, Belo Horizonte,  Brazil; Recruiting
      Hospital de Clinicas de Porto Alegre, Porto Alegre,  Brazil; Recruiting
      Hospital Santa Isabel, Blumenau,  Brazil; Recruiting
      Instituto de Cardiologia do Rio Grande do Sul, Porto Alegre,  Brazil; Recruiting
      Hospital Socor, Belo Horizonte,  Brazil; Recruiting
Brazil, MG
      Hospital Vera Cruz, Belo Horizonte,  MG,  30190-130,  Brazil; Recruiting
Brazil, PR
      Hospital Universitario Evangelico de Curitiba, Curitiba,  PR,  80730-150,  Brazil; Recruiting
Brazil, RJ
      Hospital Universitario Pedro Ernesto, Rio de Janeiro,  RJ,  20551-030,  Brazil; Recruiting
      Hospital Pro-Cardiaco S/A, Rio de Janeiro,  RJ,  22280-000,  Brazil; Recruiting
Brazil, RS
      Santa Casa de Misericoridia de Pelotas, Pelotas,  RS,  96015-290,  Brazil; Recruiting
      Hospital Sao Francisco - Irmandade da Santa Casa de Misericordia de Porto Alegre, Porto Alegre,  RS,  90020-090,  Brazil; Recruiting
      Hospital Sao Lucas da Pontificia Universidade Catolica do Rio Grande do Sul (PUCRS), Porto Alegre,  RS,  90610-000,  Brazil; Recruiting
      Hospital Mae de Deus, Porto Alegre,  RS,  Brazil; Recruiting
Brazil, SC
      Instituto de Cardiologia de Santa Catarina, Sao Jose,  SC,  88103-460,  Brazil; Recruiting
Brazil, SP
      Instituto Dante Pazzanese de Cardiologia, Sao Paulo,  SP,  04012-909,  Brazil; Recruiting
      Hospital Geral do Grajau, Sao Paulo,  SP,  04822-320,  Brazil; Recruiting
      Instituto de Molestias Cardiovasculares, Sao Jose de Rio Preto,  SP,  15015-210,  Brazil; Recruiting
      Hospital de Base, Sao Jose do Rio Preto,  SP,  15090-000,  Brazil; Recruiting
      Hospital Sao Paulo - UNIFESP/EPM, Sao Paulo,  SP,  04025-002,  Brazil; Recruiting
      Hospital e Maternidade Celso Pierro/ PUC Campinas, Campinas,  SP,  13059-740,  Brazil; Recruiting
      Conjunto Hospitalar de Sorocaba, Sorocaba,  SP,  18031-000,  Brazil; Recruiting
      Santa Casa de Misericordia de Marilia - Instituto do Coracao, Marilia,  SP,  17515-000,  Brazil; Recruiting
Bulgaria
      Military Medical Academy, Sofia,  Bulgaria; Recruiting
      Medical Institute - Central Clinical Base - Ministry of Interior, Sofia,  Bulgaria; Recruiting
      MHAT - Pleven EAD, Pleven,  Bulgaria; Recruiting
      2nd MHAT - Sofia, Sofia,  Bulgaria; Recruiting
      5th MHAT Sofia, Sofia,  Bulgaria; Recruiting
      MHAT - Plovdiv, Plovdiv,  Bulgaria; Recruiting
      MHAT Rousse EAD, Rousse,  Bulgaria; Recruiting
      MHAT - Haskovo, Haskovo,  Bulgaria; Recruiting
      MHAT St. Marina, Varna,  Bulgaria; Recruiting
Canada, British Columbia
      Kelowna General Hospital, Kelowna,  British Columbia,  Canada; Recruiting
      St. Paul's Hospital, Vancouver,  British Columbia,  Canada; Recruiting
      Ridge Meadows Hospital, Maple Ridge,  British Columbia,  Canada; Recruiting
Canada, Ontario
      Hamilton Health Sciences - General Site, Hamilton General Hospital, Hamilton,  Ontario,  L8L 2X2,  Canada; Recruiting
      Niagara Health System - Greater Niagara General Site, Niagara Fall,  Ontario,  Canada; Recruiting
      Henderson Hospital, Hamilton,  Ontario,  Canada; Recruiting
Canada, Quebec
      Montreal Heart Institute, Montreal,  Quebec,  Canada; Recruiting
Chile
      Hospital Clinico de la Pontificia Unversidad Catolica de Chile, Santiago,  Chile; Recruiting
      Hospital de Urgencia de la Asistencia Publica, Santiago,  Chile; Recruiting
      Hospital Barros Luco Trudeau, Santiago,  Chile; Recruiting
      Hospital Regional de Temuco, Temuco,  Chile; Recruiting
      Hospital del Salvador, Providencia,  Chile; Recruiting
      Hospital DIPRECA, Santiago,  Chile; Recruiting
China
      Queen Mary Hospital, Hong Kong,  China; Recruiting
Croatia
      Clinical Hospital Centre Rijeka, Rijeka,  51000,  Croatia; Recruiting
      Clinical Hospital Split, Split,  21000,  Croatia; Recruiting
      Clinical Hospital Dubrava, Zagreb,  10000,  Croatia; Recruiting
      University Hospital Sestre milosrdnice, Zagreb,  10000,  Croatia; Recruiting
      Clinical Hospital Centre Rebro, Zagreb,  Croatia; Recruiting
Czech Republic
      Nemocnice Slany, Slany,  Czech Republic; Recruiting
      Nemocnice Trebic, Trebic,  Czech Republic; Recruiting
      Nemocnice Ceske Budejovice, Ceske Budejovice,  Czech Republic; Recruiting
      Masarykova nemocnice, Usti nad Labern,  Czech Republic; Recruiting
      Fakultni nemocnice v Motole, Praha,  Czech Republic; Recruiting
      FN Ostrava, Ostrava - Poruba,  Czech Republic; Recruiting
      Nemocnice s ambulantni casti, Kutna Hora,  Czech Republic; Recruiting
      Krajska nemocnice Liberec, Liberec,  Czech Republic; Recruiting
      FN Brno - Bohunice, Brno,  Czech Republic; Recruiting
      IKEM, Praha,  Czech Republic; Recruiting
      Faculty Hospital Kralovske Vinohrady, Praha,  Czech Republic; Recruiting
      Krajska nemocnice Pardubice, Pardubice,  Czech Republic; Recruiting
Denmark
      Aarhus University Hospital, Aarhus,  DK-8000,  Denmark; Recruiting
      Centralsygehuset Esbjerg, Esbjerg,  6700,  Denmark; Recruiting
      Odense Universitets Hospital, Odense,  5000,  Denmark; Recruiting
      Copenhagen University Hospital, Copenhagen,  2100,  Denmark; Recruiting
      Gentofte University Hospital, Hellerup,  DK-2900,  Denmark; Recruiting
Estonia
      Tartu University Clinics, Tartu,  51014,  Estonia; Recruiting
Finland
      Central Ostrobothnia Central Hospital, Kokkola,  67200,  Finland; Recruiting
      Oulu University Hospital, Oulu,  Finland; Recruiting
France
      Hopital Jean Minjoz, Besancon,  France; Recruiting
      Hopital Bon Secours, Metz,  France; Recruiting
      Hopital Bichat, Paris,  France; Recruiting
      CHU de Caen, Caen,  France; Recruiting
      CHU de Rangueil, Toulouse,  France; Recruiting
      Hopital de la SSM, Freyming Merlebach,  France; Recruiting
      Cliniques des Franciscaines, Nimes,  France; Recruiting
      Centre Hospitalier de Belfort, Belfort,  France; Recruiting
      CHU Pasteur, Nice,  France; Recruiting
      Hopital Henri Mondor, Creteil,  France; Recruiting
      Hopital Cardiologique, Lyon,  France; Recruiting
      Hopital G Montpied, Clermont-Ferrand,  France; Recruiting
      Centre Hospitalier Dr Duchenne, Boulogne-sur-Mer,  France; Recruiting
      Polyclinique du Bois, Lille,  France; Recruiting
      Hopital Trousseau, Tours,  France; Recruiting
      Hospitaux Universitaires de Strasbourg, Strasbourg,  France; Recruiting
Germany
      University of Berlin - Charite of the Humboldt, Berlin,  10117,  Germany; Recruiting
      Medizinische Klink II - Klinikum Saarbrucken, Saarbrucken,  66119,  Germany; Recruiting
      Klinikum Nurnberg, Nurnberg,  90471,  Germany; Recruiting
      Johannes-Gutenberg-Universitaet Mainz, Mainz,  D-55101,  Germany; Recruiting
      Krankenhaus Heidenheim, Heidenheim,  89522,  Germany; Recruiting
      Staedtische Kliniken Offenbach, OFFENBACH,  Germany; Recruiting
      Stadtkrankenhaus Russelsheim, Russelsheim,  Germany; Recruiting
      Medizinische Hochschule Hannover, Hannover,  Germany; Recruiting
      HSK, Dr.-Horst-Schmidt-Kliniken GmbH, Wieshaden,  Germany; Recruiting
      St.-Marien-Krankenhaus Siegen, Siegen,  Germany; Recruiting
      Klinikum der Universitat Munchen, Munchen,  Germany; Recruiting
      Universitatsklinikum Hamburg-Eppendorf, Hamburg,  Germany; Recruiting
      Uni-Klinikum Benjamin Franklin, FU Berlin, Berlin,  Germany; Recruiting
      Kreiskrankenhaus Waldbrol, Waldbrol,  Germany; Recruiting
      Knappschafts Krankenhaus, Recklinghausen,  Germany; Recruiting
      St. Johannes Hospital Dortmund, Dortmund,  Germany; Recruiting
      Institut fur Herz-Kreislaufforschung, Bad Rothenfelde,  Germany; Recruiting
      St. Josefs Hospital, Wiesbaden,  Germany; Recruiting
      Abteilung Innere Medizin II, Monchengladbach,  Germany; Recruiting
      St. Sixtus Hospital, Haltern,  Germany; Recruiting
      Herzzentrum Duisburg, Duisburg,  Germany; Recruiting
      Helios Klinikum Wuppertal, Wuppertal,  Germany; Recruiting
      Medizinische Klinik und Poliklinik, Universitatsklinikum Heidelberg, Heidelberg,  Germany; Recruiting
      Krankenhaus Dueren, Dueren,  Germany; Recruiting
      Klinikum der Medizinischen Fakultat der Martin-Luther Universitat, Halle,  Germany; Recruiting
Hong Kong
      Prince of Wales Hospital, Shatin,  Hong Kong; Recruiting
Hungary
      Szent Istvan Hospital, Budapest,  Hungary; Recruiting
Italy
      Bentivoglio Hospital, Bologna,  40010,  Italy; Recruiting
      "Monzino" Cardiology Center, Milan,  20138,  Italy; Recruiting
      Ospedale Policlinico San Matteo, Pavia,  27100,  Italy; Recruiting
      Presidio Ospedaliero di Cittadella, Cittadella (Padova),  Italy; Recruiting
      Presidio Ospedaliero di Pistoia - UTIC, Pistoia,  Italy; Recruiting
      Ospedale Madonna delle Grazie, Matera,  Italy; Recruiting
      Belcolle Hospital, Viterbo,  Italy; Recruiting
      Ospedale Santa Corona, Savona,  Italy; Recruiting
      Hospital C.G. Mazzoni, Rome,  Italy; Recruiting
      Presidio Ospedaliero G. Fucito, Salerno,  Italy; Recruiting
      San Giovanni Battista "Le Molinette" Hospital, Turin,  Italy; Recruiting
      Ospedale Santa Croce, Castelnuovo Garfagnana (Lucca),  Italy; Recruiting
      Ospedale C.G. Mazzoni, Ascoli Piceno,  Italy; Recruiting
      Presidio Ospedaliero, San Bonifacio,  Italy; Recruiting
Korea, Republic of
      St. Paul's Hospital, Seoul,  130-709,  Korea, Republic of; Recruiting
      Seoul National University Hospital, Seoul,  110-744,  Korea, Republic of; Recruiting
      Severance Hospital, Seoul,  120-752,  Korea, Republic of; Recruiting
      Kyngpook National University Hospital, Dae-gu,  700-721,  Korea, Republic of; Recruiting
Korea, Republic of, Kwangju
      Chonnam National University Hospital, Dong-gu,  Kwangju,  501-757,  Korea, Republic of; Recruiting
Latvia
      P. Stradina Clinical University Hospital, Riga,  LV-1002,  Latvia; Recruiting
      Riga's 1st Hospital, Riga,  LV-1001,  Latvia; Recruiting
Lithuania
      Kaunas University of Medicine Hospital, Kaunas,  3007,  Lithuania; Recruiting
      Vilnius University Hospital - Santariskiu Clinic, Vilnius,  2021,  Lithuania; Recruiting
Malaysia
      Institut Jantung Negara, Kuala Lumpur,  50400,  Malaysia; Recruiting
      Department of Cardiology - Penang Hospital, Penang,  10990,  Malaysia; Recruiting
      Hospital Sultanah Aminah, Johor Bahru,  Malaysia; Recruiting
      Hospital Kota Bahru, Kelantan,  Malaysia; Recruiting
      Queen Elizabeth Hospital, Sabah,  Malaysia; Recruiting
Malaysia, Sarawak
      Department of Cardiology - Sarawak General Hospital, Kuching,  Sarawak,  93586,  Malaysia; Recruiting
Mexico
      Hospital Regional "Dr. Valentin Gomez Farias" ISSSTE, Zapopan Jalisco,  Mexico; Recruiting
      Hospital Bernardette S.A. de C.V., Guadalajara,  Mexico; Recruiting
      Hospital Juarez de Mexico, Mexico,  Mexico; Recruiting
      Hospital Central Norte de Petroleos Mexicanos, Del Azcapotzalco,  Mexico; Recruiting
      Hospital de Cardiologia, Mexico, D.F.,  Mexico; Recruiting
Mexico, Jalisco
      Hospital General Regional (HGR) No. 45, Instituto Mexicano del Seguro Social (IMSS), Guadalajara,  Jalisco,  Mexico; Recruiting
      Hospital General Regional 110, IMSS, Guadalajara,  Jalisco,  Mexico; Recruiting
      Hospital "Dr. Angel Leano", Zapopan,  Jalisco,  Mexico; Recruiting
      Hospital de Especialidades, Guadalajara,  Jalisco,  Mexico; Recruiting
Netherlands
      Onze Lieve Vrouwe Gasthuis, Amsterdam,  Netherlands; Recruiting
      Catharina Ziekenhuis, Eindhoven,  Netherlands; Recruiting
      Maaslandziekenhuis Sittard, Sittard,  Netherlands; Recruiting
      Medisch Centrum Alkmaar, Alkmaar,  Netherlands; Recruiting
      Groene Hart Ziekenhuis, lokatie Bleuland, Gouda,  Netherlands; Recruiting
      Isala Klinieken, lokatie Weezenlanden, Zwolle,  Netherlands; Recruiting
      Westfries Gasthuis, Hoorn,  Netherlands; Recruiting
      St. Antonius Ziekenhuis, Nieuwegein,  Netherlands; Recruiting
      Bernhoven Ziekenhuis, Lokatie Oss, Oss,  Netherlands; Recruiting
New Zealand
      North Shore Hospital, Auckland,  New Zealand; Recruiting
      Hawkes Bay Hospital, Hastings,  New Zealand; Recruiting
      Nelson Hospital, Nelson,  New Zealand; Recruiting
      Tauranga Hospital, Tauranga,  New Zealand; Recruiting
      Auckland City Hospital and Greenlane Clinical Centre, Auckland,  New Zealand; Recruiting
      Waikato Hospital, Hamilton,  New Zealand; Recruiting
      Wellington Hospital, Wellington South,  New Zealand; Recruiting
Norway
      The Hospital in Vestfold, Tonsberg,  N-3103,  Norway; Recruiting
Poland
      Szpital Grochowski im. dr med. Rafala Masztaka, Warszawa,  04-073,  Poland; Recruiting
      Wojewodzki Szpital Specjalistyczny, Olsztyn,  10-561,  Poland; Recruiting
      Oddzial Kardiologii z Pododdzialem Intensywnej Opieki Kardiologicznej, Swidnik,  21-040,  Poland; Recruiting
      Wojewodzki Szpital Zespolony, Skierniewice,  96-100,  Poland; Recruiting
      Szpital Miejski im. J. Brudzinskiego, Gdynia,  81-348,  Poland; Recruiting
      Szpital Morski im. PCK, Gdynia,  81-519,  Poland; Recruiting
      Szpital Specjalistyczny sw. Wojciecha - Adalberta, Gdansk,  80-462,  Poland; Recruiting
      Szpital Specjalistyczny w Wejherowie, Wejherowo,  84-200,  Poland; Recruiting
      SP Szpital Kliniczny Nr 7, Katowice,  40-635,  Poland; Recruiting
      Szpital Specjalistyxzny w Zabrzu, Zabrze,  41-800,  Poland; Recruiting
      Wojewodzkie Centrum Medyczne, Opole,  45-418,  Poland; Recruiting
      Specjalistyczny Szpital Im. A. Sokolowskiego, Walbrzych,  58-300,  Poland; Recruiting
      Spzoz Im J. Sniadeckiego, Nowy Sacz,  33-300,  Poland; Recruiting
      Samodzielny Szpital Wojewodzki im. Mikolaja Kopernika, Piotrkow Trybunalski,  97-300,  Poland; Recruiting
      Szpital Powiatowy, Radomsko,  97-500,  Poland; Recruiting
      Specjalistyczny Szpital Miejski im. M. Kopernika, Torun,  87-100,  Poland; Recruiting
      Wojewodzki Szpital Zespolony, Konin,  62-510,  Poland; Recruiting
      Szpital Wojewodzki w Poznaniu, Poznan,  60-479,  Poland; Recruiting
      Uniwetsytecki Szpital Kliniczny nr 3, Lodz,  91-425,  Poland; Recruiting
      Samodzielny Publiczny Zaklad Opieki Zdrowotnej Dzialdowo, Dzialdowo,  13-200,  Poland; Recruiting
      Wojewodzki Szpital Brodnowski, Warszawa,  Poland; Recruiting
      Szpitala Powiatowego w Sochaczewie, Sochaczew,  Poland; Recruiting
      Radomski Szpital Specjalistyczny, Radom,  Poland; Recruiting
      Samodzielny Publiczny Szpital Kliniczny nr 7, Katowice,  Poland; Recruiting
      Szpital Miejski nr 2, Ruda Slaska,  Poland; Recruiting
      Miedziowego Centrum Zdrowia S.A., Lubin,  Poland; Recruiting
      Szpital Wojewodzki im. sw. Lukasza, Tarnow,  Poland; Recruiting
      Samodzielny Publiczny Szpital Wojewodzki im. Papieza Jana Pawla II, Zamosc,  Poland; Recruiting
      Powiatowy Zaklad Opieki Zdrowotnej, Starachowice,  Poland; Recruiting
      Szpital Miejski im. dr. T. Chalubinskiego, Czestochowa,  Poland; Recruiting
      Oddzial Kardiologii, Ostrowiec Swietokrzyski,  Poland; Recruiting
      SP ZOZ, Szpital Specjalistyczny, Pulawy,  Poland; Recruiting
      Specjalistyczny Szpital im. E. Szczeklika, Tarnow,  Poland; Recruiting
Portugal
      Hospital Infante D. Pedro, Aveiro,  Portugal; Recruiting
      Hospital de Santo Andre, Leiria,  Portugal; Recruiting
      Hospital Garoia de Orta, S.A., Almada,  Portugal; Recruiting
Romania
      Emergency Clinical County Hospital Arad, Arad,  Romania; Recruiting
      "Sf. Spiridon" Emergency Clinical County Hospital, Iasi, Iasi,  Romania; Recruiting
      County Clinical Hospital Oradea, Oradea,  Romania; Recruiting
      'N. Stancioiu' Heart Institute Cluj-Napoca, Cluj Napoca,  Romania; Recruiting
      Emergency County Hospital Brasov, Brasov,  Romania; Recruiting
      Institute of Cardiovascular Diseases Timisoara, Timisoara,  Romania; Recruiting
      Caritas Clinical Hospital Bucharest, Bucharest,  Romania; Recruiting
      Coltea Emergency Hospital, Bucharest, Bucharest,  Romania; Recruiting
      'Elias' Emergency Clinical County Hospital, Bucharest,  Romania; Recruiting
      Colentina Clinical Hospital, Bucharest, Bucharest,  Romania; Recruiting
      Center of Cardiology Craiova, Craiova,  Romania; Recruiting
Russian Federation
      Institute of Clinical Cardiology of Cardiology Research Centre, Moscow,  121552,  Russian Federation; Recruiting
      Veteran's Hospital #3, Moscow,  129336,  Russian Federation; Recruiting
      City Clinical Hospital #29, Moscow,  111020,  Russian Federation; Recruiting
      Central Clinical Hospital of President Medical Center of Russian Federation, Moscow,  121536,  Russian Federation; Recruiting
      Cardiology Research Institute, St. Petersburg, St Petersburg,  194156,  Russian Federation; Recruiting
      Medical Foundation "Novaya Bolnitsa" as a base of Ural State Medical Academy, Ekaterinburg,  620109,  Russian Federation; Recruiting
      Tumen Cardiology Centre, Tumen,  625026,  Russian Federation; Recruiting
      Central Medical Sanitary Hospital #51, Zheleznogorsk,  662971,  Russian Federation; Recruiting
      Yaroslavl Regional Hospital, Yaroslavl,  150062,  Russian Federation; Recruiting
      City Clinical Hospital #4, Moscow,  113093,  Russian Federation; Recruiting
      City Hospital #20, Moscow,  129349,  Russian Federation; Recruiting
      City Hospital #23, Moscow,  109240,  Russian Federation; Recruiting
      City Clinical Hospital #11, Moscow,  103473,  Russian Federation; Recruiting
      Federal State Institution Clinical Hospital of President Administration of Russian Federation, Moscow,  Russian Federation; Recruiting
      City Hospital # 6, Moscow,  Russian Federation; Recruiting
      City Clinical Hospital #33, Moscow,  Russian Federation; Recruiting
      City Clinical Hospital #36, Moscow,  Russian Federation; Recruiting
      City Clinical Hospital #64, Moscow,  Russian Federation; Recruiting
      City Clinical Hospital #64, Moscow,  Russian Federation; Recruiting
      St-Petersburg Hospital #28, St Petersburg,  Russian Federation; Recruiting
      Regional Clinical Hospital #3, Volgograd,  Russian Federation; Recruiting
      Saratov Institute of Cardiology, Saratov,  Russian Federation; Recruiting
      Travel Hospital, St Petersburg,  Russian Federation; Recruiting
      St-George Hospital, St Petersburg,  Russian Federation; Recruiting
      Pokrovskaya City Hospital, St Petersburg,  Russian Federation; Recruiting
      City Hospital #15, St Petersburg,  Russian Federation; Recruiting
      St-George Hospital, St Petersburg,  Russian Federation; Recruiting
      Alexandrovsky Hospital, St Petersburg,  Russian Federation; Recruiting
      City Clinical Hospital #15, Moscow,  Russian Federation; Recruiting
      Voronezh Regional Clinical Hospital #1, Voronezh,  Russian Federation; Recruiting
      Institute of Therapy of Siberian Department of RAMS, Novosibirsk,  Russian Federation; Recruiting
      Scientific Research Institute of Cardiology of Tomsk Scientific Centre of Syberian Department of RAMS, Tomsk,  Russian Federation; Recruiting
      Central Medical Sanitary Hospital #122, St Petersburg,  Russian Federation; Recruiting
      City Clinical Hospital #70, Moscow,  Russian Federation; Recruiting
      Voronezh City Clinical Hospital of Emergency Medicine, Voronezh,  Russian Federation; Recruiting
      Main Military Hospital named by Burdenko, Moscow,  Russian Federation; Recruiting
      Moscow Medical Sechenov Academy, Moscow,  Russian Federation; Recruiting
      City Hospital No. 51, Moscow,  Russian Federation; Recruiting
Singapore
      Department of Cardiology - Changi General Hospital, Changi,  529889,  Singapore; Recruiting
Slovakia
      University Hospital - Spitalska, Nitra,  950 01,  Slovakia; Recruiting
      Slovak Heart Institute (SUSCH), Bratislava,  833 48,  Slovakia; Recruiting
      University Hospital, Martin,  036 59,  Slovakia; Recruiting
      Middle Slovak Heart Institute (SUSCH), Banska Bystrica,  Slovakia; Recruiting
Slovenia
      University Medical Centre Ljubljana, LJUBLJANA,  Slovenia; Recruiting
      General Hospital Celje, Celje,  Slovenia; Recruiting
      General Hospital Izola, Izola,  Slovenia; Recruiting
      General Hospital Maribor, MARIBOR,  Slovenia; Recruiting
      General Hospital Novo Mesto, Novo Mesto,  Slovenia; Recruiting
South Africa
      Cardiac Clinic - Groote Schuur Hospital, Cape Town,  7925,  South Africa; Recruiting
      Department of Cardiology - Universitas Hospital, Bloemfontein,  9301,  South Africa; Recruiting
      Rosepark Hospital, Bloemfontein,  9301,  South Africa; Recruiting
      DJW Navorsing, Krugersdorp,  1739,  South Africa; Recruiting
      Chris Hani Baragwanath Hospital, Soweto,  1804,  South Africa; Recruiting
      Tijger Trials Centre - Karl Bremer Hospital, Bellville,  7531,  South Africa; Recruiting
      Vergelegen MediClinic, Somerset West,  7130,  South Africa; Recruiting
      Hottentots Holland Hospital, Somerset West,  7130,  South Africa; Recruiting
      Lenmed Clinic, Lenasia,  1827,  South Africa; Recruiting
      GF Jooste Hospital, Mannenberg,  7764,  South Africa; Recruiting
      George Hospital, George,  South Africa; Recruiting
Spain
      Hospital Clinico San Carlos, Madrid,  Spain; Recruiting
      Hospital Central de Asturias, Oviedo,  Spain; Recruiting
      Hospital Clinic i Provincial, Barcelona,  Spain; Recruiting
      Hospital Universitario La Paz, Madrid,  Spain; Recruiting
      Hospital Universitario Dr. Peset, Valencia,  Spain; Recruiting
      Hospital Clinico Virgen de la Victoria, Malaga,  Spain; Recruiting
      Hospital Universitario Virgen de la Macarena, Sevilla,  Spain; Recruiting
      Hospital 12 de Octubre, Madrid,  Spain; Recruiting
      Hospital Son Dureta, Palma de Mallorca,  Spain; Recruiting
      Hospital General de Valencia, Valencia,  Spain; Recruiting
      Hospital General de Jerez de la Frontera, Cadiz,  Spain; Recruiting
      Hospital Nuestra Senora de Valme, Sevilla,  Spain; Recruiting
Sweden
      Akademiska sjukhuset, Uppsala,  751 85,  Sweden; Recruiting
      Vasterviks sjukhus, Vastervik,  593 81,  Sweden; Recruiting
      Medicinkliniken Lasarett, Motala,  591 85,  Sweden; Recruiting
      Universitetssjukhuset, Linkoping,  581 85,  Sweden; Recruiting
      Hoglandssjukhuset, Eksjo,  575 81,  Sweden; Recruiting
      Malarsjukhuset, Eskilstuna,  631 88,  Sweden; Recruiting
      Universitetssjukhuset, Lund,  Sweden; Recruiting
      Orebro Universitetssjukhus, OREBRO,  Sweden; Recruiting
      Lanssjukhuset, Sundsvall,  Sweden; Recruiting
Switzerland
      Cardiocentro Ticino, Lugano,  Switzerland; Recruiting
      Herzklinik Bodensee am Weinberg, Kreuzlingen,  Switzerland; Recruiting
Taiwan, Province of China
      Chang Gung Memorial Hospital, Kaohsiung Hsien,  123,  Taiwan, Province of China; Recruiting
      Mackay Memorial Hospital, Taipei,  92,  Taiwan, Province of China; Recruiting
      National Taiwan University Hospital, Taipei,  Taiwan, Province of China; Recruiting
Ukraine
      Central City Clinical Hospital, Kiev,  01023,  Ukraine; Recruiting
      Kiev Clinical Emergency Care Hospital, Kiev,  02660,  Ukraine; Recruiting
      Clinical Railway Hospital No. 1, Kiev,  03049,  Ukraine; Recruiting
      Central Clinical Hospital No. 5, Kharkov,  61018,  Ukraine; Recruiting
      City Hospital No. 1, Mykolayiv,  54003,  Ukraine; Recruiting
      Regional Clinical Cardio Preventive Center, Ivano-Frankovsk,  76025,  Ukraine; Recruiting
      City Joint Emergency Hospital, Dnepropetrovsk,  49005,  Ukraine; Recruiting
      Ukranian Institute of Cardiology, Kiev,  Ukraine; Recruiting
      City Clinical Hospital No. 1, Kiev,  Ukraine; Recruiting
      City Hospital #27, Kharkov,  Ukraine; Recruiting
      Donetsk State Medical University, Donetsk,  Ukraine; Recruiting
      Lviv Regional State Clinical Treatment-and-Diagnostic Cardiology Center, Lviv,  Ukraine; Recruiting
      City Clinical Hospital #3, Odessa,  Ukraine; Recruiting
      City Clinical Urgent Hospital No. 6, Crimea,  Ukraine; Recruiting
      City Clinical Hospital No. 1, Vinnitsa,  Ukraine; Recruiting
      Zaporozhye Regional Clinical Hospital, Zaporozhye,  Ukraine; Recruiting
      City Clinical Hospital #8, Kharkov,  Ukraine; Recruiting
      Institute of Recovery and Urgent Surgery, Donetsk,  Ukraine; Recruiting
      Zaporozhye Regional Cardiology Dispensary, Zaporozhye,  Ukraine; Recruiting
      Lugansk Multifield City Clinical Hospital No. 1, Lugansk,  Ukraine; Recruiting
United Kingdom
      Scunthorpe District General Hospital, Scunthorpe,  United Kingdom; Recruiting
      Torbay Hospital, Torquay,  United Kingdom; Recruiting
      OldChurch Hospital, Romford,  United Kingdom; Recruiting
      Bradford Royal Infirmary, Bradford,  United Kingdom; Recruiting
      Leeds General Infirmary, Leeds,  United Kingdom; Recruiting
      Blackpool Victoria Hospital, Blackpool,  United Kingdom; Recruiting
      Royal Hallamshire Hospital, Sheffield,  United Kingdom; Recruiting

Study ID Numbers:  63131 (MICHELANGELO:OASIS-6)
Record last reviewed:  July 2004
Record first received:  July 8, 2003
ClinicalTrials.gov Identifier:  NCT00064428
Health Authority: United States: Food and Drug Administration
ClinicalTrials.gov processed this record on 2004-11-10