Birth Defects Birth defects are the leading cause of infant mortality in the United States, accounting for more than 20% of all infant deaths. Of about 120,000 U.S. babies born each year with a birth defect, 8,000 die during their first year of life. In addition, birth defects are the fifth-leading cause of years of potential life lost and contribute substantially to childhood morbidity and long-term disability.   View by Topic Fetal Alcohol Syndrome Folic Acid Hereditary Blood Disorders ABCs of having a healthy pregnancy Not all birth defects can be prevented, however actions can be taken to increase a woman's chance of having a healthy baby....more Birth Defects Research To prevent birth defects, we need to learn more about their causes. Learn about CDC's birth defects research projects....more Basic facts about birth defects What is a birth defect? Which are most common? Learn answers to these and other frequently asked questions...more Bleeding and clotting disorders in women Read the latest article describing how these disorders relate to reproductive issues...more Anthrax Guidelines Review guidelines for pregnant women who have been exposed to anthrax but do not have symptoms....more