ARS Patent:Continuous Process for the Production of Lactulose for Lactose Using Boric Acid as a Complexion Agent patent (5895814)

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Continuous Process for the Production of Lactulose for Lactose Using Boric Acid as a Complexion Agent

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Patent Number: 5895814
Docket Number: 7894
Serial Number: 8510065
Date Patented: 04/20/1999

Continuous Process for the Production of Lactulose for Lactose Using Boric Acid as a Complexaion Agent

Technology Description:

The invention is an improved method of preparing lactulose, a non-caloric, complex carbohydrate. It is a valued pharmaceutical with applications as a laxative and as a treatment of disorders involving the brain. Lactose is converted to lactulose, followed by joining lactulose to boric acid. The lactulose-borate compound is split in acidic solution, the boric acid is crystallized, and the two components are separated by filtration, concentration, and column chromatography.

Reference:

Please refer to Patent Number 5,895,814, which issued on August 1, 1995.

Inventors:

Michael Kozempel Kevin Hicks

USDA-ARS-ERRC USDA-ARS-ERRC

Philadelphia, PA Philadelphia, PA

(215) 233-6588 (215) 233-6579

Michael Kurantz James Craig

USDA-ARS-ERRC USDA-ARS-ERRC

Philadelphia, PA Philadelphia, PA

(215) 233-6451 (215) 233-6589