Challenge 1:
Reduce catheter-associated adverse events by 50% among patients in healthcare settings

Challenge 2:
Reduce targeted surgical adverse events by 50%

Challenge 3:
Reduce hospitalizations and mortality from respiratory tract infections among long-term care patients by 50%

Challenge 4:
Reduce targeted antimicrobial-resistant bacterial infections by 50% by:
• preventing infections
• diagnosing and treating infections appropriately
• optimizing antimicrobial use, and
• preventing transmission in healthcare settings

Challenge 5:
Eliminate laboratory errors leading to adverse patient outcomes

Challenge 6:
Eliminate occupational needlestick injuries among healthcare personnel

Challenge 7:
Achieve 100% adherence to ACIP (Advisory Committee on Immunization Practices) guidelines for immunization of healthcare personnel