U.S. Food and Drug Administration
Center for Food Safety and Applied Nutrition
NCBI/NLM/NIH Glossary
- trimethoprim-sulfamethoxazole combination
- 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide mixture with 5-((3,4,5-trimethoxyphenyl)methyl)- 2,4-pyrimidinediamine. This drug combination has proved to be an effective therapeutic agent with broad-spectrum antibacterial activity against both gram-positive and gram-negative organisms. It is effective in the treatment of many infections, including Pneumocystis carinii pneumonia in AIDS, but is the drug of choice for urinary infection