NCEH in Partnership with Maryland
The National Center for Environmental Health (NCEH) is part of the
Centers for Disease Control and Prevention (CDC). NCEH’s work
focuses on three program areas: identifying environmental hazards,
measuring exposure to environmental chemicals, and preventing
health effects that result from environmental hazards. NCEH has
approximately 450 employees and a budget for 2004 of approximately
$189 million; its mission is to promote health and quality of life
by preventing or controlling diseases and deaths that result from
interactions between people and their environment.
NCEH and partners in Maryland collaborate on a variety of
environmental health projects throughout the state. In fiscal
years 2000–2004, NCEH awarded more than $13 million in
direct funds and services to Maryland for various projects. These
projects include activities related to addressing asthma, studying
age-related eye diseases, and inspecting cruise ships. In
addition, Maryland benefits from national-level prevention and
response activities conducted by NCEH or NCEH-funded partners.
Identifying Environmental Hazards
NCEH identifies, investigates, and tracks environmental hazards
and their effects on people’s health. Following are examples of
such activities that NCEH conducted or supported in Maryland.
Asthma
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Addressing Asthma from a Public
Health Perspective—NCEH is funding the Maryland
Department of Health and Mental Hygiene (DHMH) to develop
asthma-control plans that include disease tracking,
science-based interventions, and statewide partnerships to
reduce the burden of asthma in home, school, and occupational
environments. Funding began in fiscal year 2001 and continues
through fiscal year 2004.
Environmental Public Health Studies
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Multistate Surveillance System
for Possible Estuary-Associated Syndrome (PEAS)—NCEH is
funding DHMH to research the nature and possible health
effects of Pfiesteria piscicida (P. piscicida), a
microscopic alga that lives in estuaries and has been found near
large groups of dead fish. Although scientists do not know
whether P. piscicida affects human health, anecdotal
reports about symptoms such as headache, confusion, rash, and
eye irritation in humans exposed to water containing high
concentrations of P. piscicida have generated public
concerns. To assist in responding to these concerns the project
is (1) maintaining and expanding the Marine and Freshwater
hotline and a harmful algal blooms Web site, (2) expanding
surveillance activities by linking existing environmental
monitoring data to surveillance data, (3) developing GIS
applications to link data sets in time and space, and (4)
analyzing a cohort study that was conducted with earlier
funding. Funding began in fiscal year 1998 and is ongoing.
Environmental Public Health Tracking
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National Environmental Public
Health Tracking Program: Planning and Capacity Building—NCEH
is funding DHMH to launch, coordinate, and oversee
progress for the Maryland Environmental Health Tracking
Initiative. DHMH is working through an interagency coordinating
group that includes the Maryland Department of the
Environment to accomplish these tasks. The group plans
action steps, sets interim goals and deadlines, addresses
problems, ensures task completion, and ensures collaboration and
stakeholder involvement. Funding began in fiscal year 2002 and
continues through fiscal year 2004.
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National Environmental Public
Health Tracking Program: Centers of Excellence in Environmental
Public Health Tracking—NCEH is funding the Johns Hopkins
School of Public Health Center of Excellence in Environmental
Public Health Tracking to strengthen the environmental
health workforce through training and education, provide
technical assistance and research support for the development of
the Environmental Public Health Tracking Network, and conduct
research to investigate links between the environment and health
effects. Center efforts will be shaped by partnerships with
participating state and local agencies, national health and
environmental organizations, CDC, and NCEH. Funding began in
fiscal year 2002 and ends in fiscal year 2004.
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Measuring Exposure to Environmental
Chemicals
NCEH measures environmental chemicals in people to determine how
to protect people and improve their health. Following are examples
of such activities that NCEH conducted or supported in Maryland.
Funding
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Antiterrorism Funding to Increase
State Chemical Laboratory Capacity—In fiscal year 2003, CDC
provided more than $910,000 to Maryland to help expand
chemical laboratory capacity to prepare for and respond to
chemical-terrorism incidents and other chemical emergencies.
This expansion will allow full participation of
chemical-terrorism response laboratories in the Laboratory
Response Network.
In addition, NCEH funds laboratory development and the purchase
of state-of-the-art equipment in public health laboratories in
Maryland to develop a network of chemical laboratories and
transfer technology to measure chemical agents.
Studies
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National Heart, Lung, and Blood
Institute (NHLBI) Premier Study—This study, which began in
1998, was a randomized, multicenter clinical trial to determine
the effects of implementing recommended lifestyle interventions
on blood pressure. The study was conducted at four clinical
centers, including Johns Hopkins University in
Baltimore. In collaboration with NHLBI, NCEH measured serum
samples for folate; carotenoids; and vitamins A, E, and B12. The
main results showed that people with above-optimum blood
pressure, including those with stage 1 hypertension, can make
multiple lifestyle changes that lower their blood pressure, thus
reducing their risk for cardiovascular disease.
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Age-Related Eye Disease Study—The
National Eye Institute conducted the Age-Related Eye Disease
Study, a 10-year multicenter study, to investigate the natural
history of age-related macular degeneration and cataracts and
the role of various risk factors in their development and
progression. The study tested the effects of nutritional
supplementation on preventing and controlling these diseases
through a randomized, placebo-controlled clinical trial. NCEH
measured serum samples for carotenoids; lipids; zinc; copper;
and vitamins A, E, and C. Wilmer Eye Institute at
Johns Hopkins Hospital in Baltimore was one of the 10
study centers.
Study results showed that people at high risk for advanced AMD,
a leading cause of vision loss, lowered their risk by 25% when
treated with a high-dose combination of vitamins C and E,
beta-carotene, and zinc. In the same high-risk group, which
includes people with intermediate AMD or with advanced AMD in
only one eye, the nutrients reduced the risk for vision loss
caused by advanced AMD by about 19%. For study participants who
had either no AMD or who were in the early stages of AMD, the
nutrients provided no apparent benefit.
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Exposure to Environmental
Contaminants in Pregnant Women and Effects on Fetal Development—The
Johns Hopkins University School of Hygiene and Public Health
is conducting this study to evaluate exposure to environmental
toxicants in a sample of pregnant women, stratified by social
class, who live in and around Baltimore. The combination
of sophisticated techniques to measure both biologic markers of
exposure as well as fetal functioning will yield the first
comprehensive evaluation of the contemporaneous effects of
neurotoxicants on development before to birth. The overall
purpose of the study is to examine the relation between
environmental toxicants and fetal development.
The original sample was predominantly drawn from middle-class
women. The current substudy, comprising women from a prenatal
clinic that serves low-income patients, investigates earlier
findings that indicated large differences in measures of fetal
development by social class. NCEH measured polychlorinated
biphenyls and organochlorine pesticides in 50 maternal serum
samples. Fetal neurobehavioral functioning was assessed at 36
weeks gestation in normal, uncomplicated pregnancies of healthy
women. Data are being evaluated to determine whether any
relation exists between decrements to fetal development and the
concentrations of biologic contaminants in maternal serum.
Services
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Newborn Screening Quality
Assurance Program—NCEH provides proficiency-testing services
and dried-blood-spot, quality-control materials to monitor and
help assure the quality of screening program operations for
newborns in Maryland. The importance of accurate
screening tests for genetic metabolic diseases cannot be
overestimated. Testing of blood spots collected from newborns is
mandated by law in almost every state to promote early
intervention that can prevent mental retardation, severe
illness, and premature death.
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Lipid Standardization Program (LSP)—NCEH
provides two lipid research laboratories in Maryland with
accuracy-based standardization support for analytic measurement.
These laboratories are involved in one or more ongoing lipid
metabolism longitudinal studies or clinical trials that
investigate risk factors and complications associated with
cardiovascular disease. The LSP, supported by NCEH’s Lipid
Reference Laboratory, provides quarterly analytic performance
challenges and statistical assessment reports that allow program
participants to monitor performance over time and thus ensure
the accuracy and comparability of study results and findings.
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Helping State Public Health
Laboratories Respond to Chemical Terrorism—NCEH is working
with Maryland’s public health laboratory to prepare state
laboratory scientists to measure chemical-terrorism agents or
their metabolites in people’s blood or urine. NCEH is
transferring analytic methods for measuring chemical-terrorism
agents (including cyanide-based compounds and other chemicals)
to Maryland. In addition, NCEH instituted a proficiency-testing
program to measure the comparability of the state’s analytic
results with results from the NCEH laboratory.
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Preventing Health Effects That Result
from Environmental Hazards
NCEH promotes safe environmental
public health practices to minimize exposure to environmental
hazards and prevent adverse health effects. Following are examples
of such activities that NCEH conducted or supported in Maryland.
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Public Health Inspections of
Cruise Ships—NCEH established the model Vessel Sanitation
Program in 1975 to combine industry cooperation with CDC’s
ability to aggressively protect the health of travelers. The
program helps the industry develop and implement comprehensive
sanitation programs to minimize risks for gastrointestinal
diseases. Every vessel that has a foreign itinerary and carries
13 or more passengers is subject to two unannounced inspections
each year. These inspections result in safer vessels and
sanitation programs that protect the health of passengers and
crew members. In 2003, the Vessel Sanitation Program conducted
two inspections of cruise vessels with stops in Maryland.
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Childhood Lead Poisoning
Prevention Program—The Maryland Childhood Lead Poisoning
Prevention Program (MD CLPPP) has received NCEH funding
since 1991. In 2001, the program screened 74,925 children for
lead poisoning. The number of children under 6 years of age who
had elevated blood lead levels decreased from 2,668 in 2000 to
2,114 in 2001.
MD CLPPP is using NCEH funds to develop and implement a
childhood lead poisoning elimination plan, to maintain and
evaluate its targeted screening plan, and to increase targeted
primary prevention and case management activities and strategic
partnerships.
Resources
NCEH develops materials that public health professionals,
medical-care providers, emergency responders, decision makers, and
the public can use to identify and track environmental hazards
that threaten human health and to prevent or mitigate exposure to
those hazards. NCEH’s resources cover a range of environmental
public health issues. These issues include air pollution and
respiratory health (e.g., asthma, carbon monoxide poisoning, and
mold exposures), biomonitoring to determine whether selected
chemicals in the environment get into people and to what extent,
childhood lead poisoning, emergency preparedness for and response
to chemicals and radiation, environmental health services,
environmental public health tracking, international emergency and
refugee health, laboratory sciences as applied to environmental
health, radiation studies, safe disposal of chemical weapons,
specific health studies, vessel sanitation, and veterans’ health.
For more information about NCEH programs, activities, and
publications as well as other resources, contact the NCEH Health
Line toll-free at 1-888-232-6789, e-mail
NCEHinfo@cdc.gov, or visit
the NCEH Web site at
www.cdc.gov/nceh.
September 2004
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