NCEH in
Partnership With
New York
The National Center for Environmental Health (NCEH) is part of the
Centers for Disease Control and Prevention (CDC). NCEH’s work
focuses on three program areas: identifying environmental hazards,
measuring exposure to environmental chemicals, and preventing
health effects from environmental hazards. NCEH has approximately
450 employees and a budget for 2004 of approximately $189 million;
its mission is to promote health and quality of life by preventing
or controlling diseases and deaths that result from interactions
between people and their environment.
NCEH and partners throughout New York collaborate on a
variety of environmental health projects throughout the state. In
fiscal years 2000–2004, NCEH awarded more than $21.5
million in direct funds and services to New York for various
projects. These projects include activities related to asthma,
environmental public health tracking, and pesticide use among
pregnant women. In addition, New York benefits from national-level
prevention and response activities conducted by NCEH or
NCEH-funded partners.
Identifying Environmental Hazards
NCEH identifies, investigates,
and tracks environmental hazards and their effects on people’s
health. Following are examples of such activities that NCEH has
conducted or supported in New York.
Asthma
- Addressing Asthma from a
Public Health Perspective—NCEH is funding New York to
implement a comprehensive, statewide asthma-control plan.
Funding began in fiscal year 2002 and continues through fiscal
year 2005.
- Controlling Asthma in
American Cities—To decrease asthma-related morbidity, NCEH
is funding New York City to use innovative, collaborative
approaches to improve asthma management among urban children
younger than 18 years of age. Funding began in fiscal year 2002
and continues through fiscal year 2007.
- Development of Asthma-Care
Models—In fiscal year 2005, NCEH funded the Woodhull
Medical and Mental Health Center in Brooklyn to
develop and test a comprehensive model of care for children and
adolescents younger than 19 years of age who have asthma. This
model melds the education of patients and providers with
environmental assessments, follow-up care, and state-of-the-art
information technology to address the complex needs of families
managing asthma.
- Inner-City Asthma
Intervention—NCEH is funding grantees in New York to
provide inner-city families with asthma education and
individualized asthma-control plans. Funding began in fiscal
year 2002 and continues through fiscal year 2004.
- Asthma-Related Disaster
Relief—NCEH is funding New York to implement
community-level asthma interventions, asthma surveillance
activities, and environmental monitoring related to the 2001
World Trade Center disaster. Funding began in fiscal year 2002
and continues through fiscal year 2006.
- Replication and
Implementation of Scientifically Proven Asthma Interventions—NCEH
is funding two grantees in New York to implement two
scientifically evaluated asthma interventions that decrease
acute-care visits, decrease hospitalizations, and increase
compliance with asthma-care plans. The first grantee, the
Asthma and Allergy Foundation of America, is implementing
Asthma Care Training for Kids (ACT). The goals for ACT are to
increase asthma-control compliance behaviors and to decrease
emergency department visits and number of days spent in the
hospital. The second grantee, the American Lung Association,
is implementing Open Airways for Schools (OAS). The goals for
OAS are to increase school performance and self-management
behaviors and to decrease the number of asthma episodes. Funding
began in fiscal year 2001 and continues through fiscal year
2004.
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Environmental Public Health
Tracking (EPHT) Projects
- Infrastructure Enhancement
and Data-Linkage Demonstration for the National EPHT Network—NCEH
is funding a cooperative agreement with the New York State
Department of Health (NYSDOH) to evaluate the feasibility
and usefulness of linking health-effects data with
human-exposure data and environmental-hazard data. Funding began
in fiscal year 2003 and continues through fiscal year 2005. The
project’s goals are to
1. enhance the state’s ability to assess the relation between
air pollution and pregnancy outcomes, asthma development, and
childhood mortality;
2. develop the state’s ability to track the public health
significance of exposures to contaminants in drinking water; and
3. develop the state’s ability to track neurologic conditions,
autoimmune diseases, developmental disabilities, diabetes,
chronic diseases other than reproductive outcomes, cancer, and
asthma.
NYSDOH also is developing strategies for quickly communicating
information generated by the national EPHT Network to local,
tribal, and federal governments; health-care providers;
nongovernment organizations; the public; and other stakeholders.
The state also will work with the universities active in the
EPHT program to develop and provide training to state and local
staff on surveillance practices, environmental assessment,
biomonitoring, evaluation, and risk communication and to
evaluate the environmental public health indicators.
- Data-Linkage Demonstration
for the National EPHT Network—NCEH is funding two grantees—NYSDOH
and the New York City Department of Health and Mental Hygiene
(NYC DOHMH)—to conduct demonstration projects for the
national EPHT Network. The NYSDOH project will link public water
supply monitoring data geographically with birth-outcome data
according to water district. NYSDOH and NCEH will work together
to ensure that this demonstration project is compatible with the
developing national EPHT Network.
The purpose of the NYSDOH project is to demonstrate and evaluate
methods for linking data from existing health effects
surveillance systems with data from existing human exposure and
environmental hazards surveillance and monitoring systems in New
York. NCEH and its partners will use the methods, tools, and
best practices developed through this project to advance the
development of the national EPHT Network.
The NYC DOHMH project will link hazard, exposure, and
health-outcome data associated with heavy metals and pesticides.
Ongoing surveillance of these environmental and health concerns
will allow the city to report data publicly, evaluate progress
toward the reduction of heavy metals and pesticides, launch
interventions to reduce health risks, and improve environmental
quality.
Lessons learned through the NYC DOHMH project will be used to
expand the NYC DOHMH Environmental and Health Effects Tracking
program. NYC DOHMH has completed a preliminary inventory of data
related to heavy metals and pesticides, convened an advisory
panel of stakeholders, and begun assessing the city’s
technical-infrastructure needs.
Funding for both projects began in fiscal year 2004 and
continues through fiscal year 2006.
- Planning and
Capacity-Building for the National EPHT Network—NCEH is
funding a cooperative agreement with NYC DOHMH to assess,
evaluate, and enhance the city’s surveillance systems that track
health effects, exposure, and hazard surveillance data. This
project, titled Environmental Connections, will build on NYC
DOHMH’s existing environmental public health tracking systems,
and on the tracking systems of the department’s sister agencies.
Environmental Connections also will cultivate NYC DOHMH’s
partnerships with local academic institutions, community-based
organizations, private-sector employers, unions, and federal
agencies. Funding began in fiscal year 2003 and continues
through fiscal year 2005.
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Environmental Public Health
Studies Projects
- Assessing Physical and
Mental Health and Other Conditions After the Attack on the World
Trade Center in New York City—At the request of the New
York City Commissioner of Health, NCEH collaborated with and
provided technical assistance to NYC DOHMH to assess
physical and mental-health needs among lower Manhattan residents
after the September 11, 2001, attack on the World Trade Center.
Researchers found that in the three surveyed areas of lower
Manhattan, basic community services (such as utilities and
medical or pharmacy services) were available. However, residents
were tremendously concerned about air quality and its potential
effects on health. The high proportion of the local population
experiencing health problems potentially related to respiratory
irritants supported this concern. Another major concern in all
three areas surveyed was mental health. Thousands of people
living in lower Manhattan potentially may be at risk for
posttraumatic stress disorder and could benefit from supportive
mental health services. Many of these people may not have access
to or be aware of available mental health programs.
- Assessing Mercury Exposure
Among Young Children in New York City―Requested by NYC
DOHMH, this ongoing study is designed to determine whether
children in New York City communities are being exposed
to mercury, and, if so, what sources of mercury might be
responsible for exposures. Researchers will enroll a total of
400 children from three public health clinics in the study.
Parents are approached during visits to the clinics and asked to
enroll their children in the study. Researchers will seek an
additional 50 children for a door-to-door pilot study conducted
in conjunction with this study.
New York State will analyze all of the urine samples.
NCEH will analyze all of the blood samples and, for quality
control, a subset of approximately 10% of the urine samples.
Funding began in fiscal year 2004.
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Measuring Exposure to Environmental Chemicals
NCEH measures environmental
chemicals in people to determine how to protect people and improve
their health. Following are examples of such activities that NCEH
has conducted or supported in New York.
Funding
- Antiterrorism Funding to
Increase State Chemical Laboratory Capacity—In fiscal year
2003, CDC provided more than $1.4 million to New York and
more than $90,000 to New York City to assist them in
expanding chemical laboratory capacity to prepare and respond to
chemical terrorism incidents and other chemical emergencies.
This program expansion will allow for full participation of
chemical-terrorism response laboratories in the Laboratory
Response Network. NCEH also continues to fund laboratory
development and the purchase of state-of-the-art equipment in
the state’s and city’s public health laboratories in support of
developing a network of chemical laboratories and of
transferring technology to measure chemical agents.
- Biomonitoring Grants―In
fiscal years 2001 and 2002, NCEH awarded planning grants to
develop a plan for implementing a biomonitoring program for the
state. In this way, the state could make decisions about which
environmental chemicals within its borders were of health
concern and could make plans to measure levels of those
chemicals in the New York population. In 2003, New York
also received a grant to implement the biomonitoring program in
the state.
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Studies
- Pesticide Use Among
Pregnant Women in New York City―In this study, Mt. Sinai
School of Medicine’s Children’s Environmental Health Center
and NCEH collaborated to evaluate pesticide use among 426
pregnant women. The women were from three racial or ethnic
groups living chiefly in East Harlem and surrounding
neighborhoods in New York City. NCEH measured levels of
12 breakdown products (or metabolites) in the urine of these
women. The metabolites represented exposure to a range of
organophosphate and synthetic pyrethroid pesticides. Mt. Sinai
researchers investigated the prevalence of exposure in relation
not only to reported use of pesticides, race or ethnicity,
housing stock (kind and geographic location), and seasons of the
year, but also to maternal age. Study data indicate that
exposure to indoor pesticides is common and preliminary results
show that pesticide levels in urine differ by educational status
of the women and season of the year but not by reported
pesticide use during pregnancy. Data on levels of various
metabolites and demographic correlates of exposure are being
evaluated.
- The Effect of Prenatal
Exposure to Ambient and Indoor Pollutants on Birth Outcomes,
Neurocognitive Development, and DNA―In collaboration with
Columbia University’s Center for Children’s Environmental Health,
NCEH measured levels of 29 pesticides or their metabolites in
blood samples collected at birth from 142 mothers and 155
newborns enrolled in this prospective cohort study. Seven of the
pesticides, among them the organophosphate pesticides
chlorpyrifos and diazinon, were detected in 54%–97% of the
maternal and umbilical cord blood samples, and levels in these
samples were significantly correlated. However, levels of these
chemicals in the air were not correlated with blood levels. A
fungicide known as o-phenylphenol was detected in 100% of
personal air samplers worn by the pregnant women but not in
their blood samples. The remaining pesticides were detected in
less than 30% of the personal air and blood samples. Levels of
two pesticides were significantly higher in the personal air
samples of women who reported using exterminators, can sprays,
or pest bombs during pregnancy than in women who reported no
pesticide use or who used only boric acid, traps, or gels.
Findings indicate frequent, but decreasing, pesticide exposures
among this minority group, but findings also show ready transfer
of pesticides to the developing fetus. Researchers also
evaluated exposure levels in relation to adverse birth outcomes;
results indicated that prenatal exposure to the pesticide
chlorpyrifos impaired fetal growth and that exposure to diazinon
may contribute to the effects. These findings support recent
regulatory action to phase out the residential uses of certain
pesticides such as chlorpyrifos.
- Relation of Exposure to
Hormonally Active Chemicals and the Onset of Puberty in Young
Girls―Building on an earlier study which suggested that
African Americans were more likely than whites to achieve
puberty at an early age (9 years), the Mt. Sinai School of
Medicine’s Breast Cancer and Environment Center is
conducting a longitudinal study to further evaluate
environmental exposures and their impact on the onset of puberty
in young girls. NCEH will collaborate on the study and measure
levels of phytoestrogens, phthalates, alkyphenols, pesticides,
and other chemicals in the blood and urine of study
participants. This study is in the late planning stages; field
work should begin during the late summer or early fall of 2004.
- Ross School Study―For
several years, the Ross boarding school in Long Island
has promoted a wellness program that includes physical activity
and meals that contain organically produced food. To evaluate
the effectiveness of these meals in reducing overall exposure to
pesticides, NCEH collaborated with Massachusetts General
Hospital and Harvard University in a cross-sectional study of
students and faculty who ate meals prepared primarily at the
school. Meals prepared at Ross School had been hypothesized to
be lower in pesticide residues than meals that did not contain
organically produced foods. Researchers compared levels of
pesticide metabolites in this group and in a group of
age-matched people who did not eat organically produced foods.
Study data are being analyzed. Results probably will be
available in summer 2004.
- New York City Health and
Nutrition Examination Study (HANES)―Many states and cities
are keenly interested in assessing their residents’ exposure to
a host of environmental chemicals to determine whether those
levels are higher, lower, or similar to background levels in the
general U.S. population. NCEH is providing support for measuring
levels of organophosphate and pyrethroid pesticide metabolites
in a 400-sample subset of the 2,000 samples that will be
collected by New York City health officials. Study
protocols are being developed. NCEH already has transferred
methods for measuring organophosphate pesticides and trace
metals in urine and will supply quality-control materials to
NYSDOH, which eventually will analyze samples for the New
York City HANES.
- Perchloroethylene Study―NYSDOH
is evaluating exposure to the dry-cleaning chemical
perchloroethylene. Researchers will examine possible adverse
health effects (including neurologic effects) among children and
adults who live in buildings that also house dry-cleaning
facilities using this chemical. NCEH is evaluating blood levels
of perchloroethylene in both case- and control-participants.
NCEH also will measure levels of lead and mercury in the blood
and urine of study participants. The study is ongoing.
- Transdisciplinary
Tobacco-Use Research Centers/International Tobacco Consortium―This
ongoing project is a collaborative effort between the Roswell
Park Research Institute in Buffalo and NCEH. It is
designed to assess the influence of policies that regulate
product characteristics on cigarette design, the chemical
composition of smoke (also known as “smoke chemistries”),
smokers’ behaviors and perceptions, and biomarkers of exposure.
NCEH will establish and maintain a repository of cigarette packs
from multiple countries and will characterize samples from those
packs for many features, including the weight and blend of the
tobacco, filter type and weight, and filter ventilation.
NCEH will assess smoke chemistries, including substances such as
tar, nicotine, carbon monoxide, free nicotine, tobacco-specific
nitrosamines, and polycyclic aromatic hydrocarbons. The
laboratory also will assess smoking topography—how people smoke
cigarettes—using portable devices and biologic markers of
exposure. In another project, NCEH will assess changes in design
and smoke chemistries over time in various brands and will
assess smoke chemistries of fire-safe cigarettes (cigarettes
capable of self-extinguishing). Researchers will determine
whether smokers’ behaviors (e.g., reported number of cigarettes
smoked daily, puff patterns, brand switching, quitting) and
perceptions (relative hazards and acceptability of various
brands) change once changes in policy occur.
- Exposure Study of
Persistent Pollutants in Urban Anglers―This pilot study, in
collaboration with the Mt. Sinai School of Medicine, is
designed to examine the possibility of a relation between
exposure to polybrominated diphenyl ethers (PBDEs) and health
effects among people who obtain their fish and shellfish from
the Hudson River in New York Harbor. Although
adverse health effects from PBDE exposure are not well
understood, limited data support the hypothesis that PBDEs may
affect the thyroid gland and influence estrogen function.
Experimental data also indicate that PBDEs may negatively affect
the developing nervous system. NCEH will measure levels of PBDEs
as well as levels of other persistent organic
pollutants―dioxins, furans, and polychlorinated biphenyls―in the
serum of about 100 people who catch and eat fish and shellfish
from the Hudson River in New York Harbor. The laboratory is
analyzing samples.
- Assessing Exposure to
Arsenic―This ongoing study will evaluate the relation
between soil contamination from and human exposure to an
arsenical pesticide produced in a plant in Middleport.
Study participants are children younger than 7 years of age.
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Services
- Blood Lead Laboratory
Reference System (BLLRS)—In New York, 21 laboratories
participate in NCEH’s standardization program to improve the
overall quality of laboratory measurements of blood lead levels.
This program assists laboratories nationwide in evaluating their
performance on these critical laboratory tests. NCEH provides
BLLRS materials to the laboratories four times a year without
charge. Additionally, NCEH is a reference laboratory for several
New York State proficiency-testing programs involved in
analyzing other trace and toxic metals.
- Lipid Standardization
Program―CDC provides accuracy-based analytical measurement
standardization support to seven lipid research laboratories in
New York involved in one or more ongoing lipid metabolism
longitudinal studies or clinical trials investigating risk
factors and complications associated with cardiovascular
disease.
- Cholesterol Reference
Method Laboratory Network (CRMLN)―NCEH established the CRMLN
to assist manufacturers in calibrating diagnostic products used
for lipid and lipoprotein testing. The Wadsworth Center for
Laboratories and Research in NYSDOH is one of four
U.S. laboratories in the CRMLN. These laboratories use CDC
reference methods or designated comparison methods closely
linked to CDC reference methods. This ensures that diagnostic
products are properly calibrated and traceable to the accuracy
base maintained at CDC. More than 95% of the participants in the
proficiency-testing surveys of the College of American
Pathologists have been certified through the CRMLN. This is
directly attributed to manufacturers properly calibrating their
products through the CRMLN.
- Helping State Public Health
Laboratories Respond to Chemical Terrorism—NCEH is working
with New York’s public health laboratory to prepare state
laboratory scientists to measure chemical terrorism agents or
their metabolites in people’s blood or urine. NCEH has conducted
training on operating state-of-the-art laboratory instruments
and on using specific methods to analyze these agents.
Additionally, NCEH has transferred methods for measuring nerve
agents, cyanide, and trace metals to the state laboratory and
has instituted a proficiency testing program to test the
comparability of analytical results from the state laboratory
and NCEH.
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Preventing Health Effects From Environmental Hazards
NCEH promotes safe environmental
public health practices to minimize exposure to environmental
hazards and prevent adverse health effects. Following are examples
of such activities that NCEH has conducted or supported in New
York.
- New York State Childhood
Lead Poisoning Prevention Program—NYSDOH and NYC
DOHMH lead poisoning prevention programs have received CDC
funding since 1991. New York is among the states screening the
most children younger than 6 years of age for lead. In 2001, New
York and New York City together reported 432,944 children
screened for blood lead levels. Furthermore, the number of
children younger than 6 years of age with elevated blood lead
levels decreased 62% from 1997 to 2001—from 25,627 to 9,771. The
NYSDOH Health Lead Poisoning Prevention Program leverages NCEH
funds to provide funding and technical assistance to 57 local
health departments and New York City.
- Monitoring of the Emergency
Responders to the World Trade Center Attack September 11, 2001—CDC
used funds received from the Federal Emergency Management Agency
to award two grants: $4.8 million to the New York City Fire
Department and $2.3 million to NYSDOH to conduct
medical evaluations of responders at World Trade Center Ground
Zero. These medical evaluations will serve as a baseline to
monitor any long-term health outcomes associated with the rescue
workers. Evaluations and interviews are nearly complete; the
project is now in the assessment phase.
- Cruise Ship Public Health
Inspections—NCEH established the model Vessel Sanitation
Program in 1975 to combine cruise-ship industry cooperation with
CDC’s ability to take aggressive actions to protect the health
of travelers. The program assists the industry in developing and
implementing comprehensive sanitation programs to minimize risks
for gastrointestinal diseases. Every vessel that has a foreign
itinerary and carries 13 or more passengers is subject to two
unannounced inspections each year. In 2003, NCEH’s Vessel
Sanitation Program conducted 17 inspections of cruise vessels
that stopped at New York City. Since the program’s
inception, rates and outbreaks of diarrheal disease among
passengers have continued to decrease because of environmental
sanitation inspections.
- Environmental Health
Specialists Network (EHS-Net)—As part of an eight-state
cooperative agreement with NCEH and the Food and Drug
Administration (FDA), the New York EHS-Net Program has
received NCEH funding since 2000. These funds have enabled New
York to describe the number and type of retail markets,
institutions, and restaurants of the local food programs in the
New York EHS-Net catchment area and the status of the FDA Model
Food Code in these areas; to identify high-risk egg-handling
practices; to evaluate behavioral factors that influence safe
food-handling practices; and to evaluate the knowledge,
attitudes, and behaviors of environmental health specialists
regarding food safety and inspections. Thus far, New York has
performed research evaluations of many food-service
establishments (both disease and nondisease outbreaks) and has
led revision of the EHS-Net data collection instrument. New York
and the other EHS-Net partners have been working toward the
national goal of reducing foodborne disease outbreaks caused by
pathogenic organisms.
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Resources
NCEH develops materials that
public health professionals, medical-care providers, emergency
responders, decision makers, and the public can use to identify
and track hazards in the environment that threaten human health
and to prevent or mitigate exposure to those hazards. NCEH’s
resources cover a range of environmental public health issues,
including air pollution and respiratory health (e.g., asthma,
carbon monoxide poisoning, and mold exposure), biomonitoring to
determine whether and how much of selected chemicals in the
environment get into people, childhood lead poisoning, emergency
preparedness for and response to chemicals and radiation,
environmental health services, environmental public health
tracking, international emergency and refugee health, laboratory
sciences as applied to environmental health, radiation studies,
safe disposal of chemical weapons, specific health studies, vessel
sanitation, and veterans’ health.
For more information about NCEH programs, activities, and
publications and other resources, contact the NCEH Health Line
toll-free at 1-888-232-6789, e-mail NCEHinfo@cdc.gov, or visit the
NCEH Web site at
www.cdc.gov/nceh.
May 2004
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