Agent Name |
Manganese |
CAS Number |
7439-96-5 |
Formula |
Mn |
Major Category |
Metals |
Synonyms |
Manganese metal: Colloidal manganese, Manganese-55 Synonyms of other compounds vary depending upon the specific manganese compound. |
Category |
Metals, Elemental |
Description |
A lustrous, brittle, silvery solid; |
Sources/Uses |
MINING, SMELTING, AND METALLURGY: Ore mining and crushing operations; Iron and steel production; Ferrous & nonferrous alloys (for rock crushers, railroad points and crossings, etc.); MANUFACTURING: Dry-cell batteries; Anti-knock gasoline additive; Incendiary devices; Matches; Pigments for ceramics, glass, or paints; Dyes & inks; Pesticides; USING: Grind, drill, or arc weld Mn alloy; use Mn welding rods; |
Comments |
Manganese is an essential nutrient in the human diet. Daily needs are in the range of 1-10 mg per day. [ATSDR ToxProfiles] Heavy exposure to fume can cause acute pneumonitis. [Harber, p. 498] In reproductive studies, high doses can cause testicular damage in animals. [ATSDR Case Studies # 29] Manganese can accumulate in the body over time to cause chronic neurological disease. [Sullivan, p. 933] |
Reference Link |
EPA - Air Toxics Website - Manganese Compounds |
Exposure Assessment |
Skin Designation (ACGIH) |
No |
Bioaccumulates |
Yes |
TLV (ACGIH) |
0.2 mg/m3 |
PEL (OSHA) | Ceiling(OSHA) = 5 mg/m3 |
MAK |
0.5 mg/m3, inhalable fraction |
IDLH (NIOSH) |
500 mg/m3 |
Excerpts from Documentation for IDLHs |
Chronic exposures to workers averaging 47 mg/m3 caused manganese poisoning, while no cases occurred at exposures less than 30 mg/m3 [Flinn et al. 1940]. Chronic exposure to concentrations averaging 210 mg/m3 have been associated with pneumonia [Lloyd-Davies 1946]. Workers chronically exposed to concentrations of manganese dust averaging 20 mg/m3 showed signs of manganism [Smyth et al. 1973]. |
Explanatory Notes |
Melting Point = 2271 degrees F; For TLV, see ACGIH "Notice of Intended Changes." |
Half Life |
Whole body: 2-5 weeks depending on body stores; [TDR, p. 1556] |
Reference Link |
International Chemical Safety Cards (WHO/IPCS/ILO) |
Adverse Effects |
Toxic Pneumonitis |
Yes |
Neurotoxin |
Parkinson's Syndrome |
Reproductive Toxin |
Yes |
Links to Other NLM Databases |
Health Studies |
Human Health Effects from Hazardous Substances Data Bank: MANGANESE, ELEMENTAL
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