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Clinical Trial System of Future
The recent voluntary recall of rofecoxib (Vioxx) by Merck & Co., Inc., illustrates all too well the importance of well-designed clinical trials and vigilant surveillance for any new drug or medical product. Some 3 years after FDA approval and widespread use, rofecoxib was found to be associated with a two-fold increased risk of cardiovascular toxicities in people who took the drug for 18 months or longer in a clinical trial to prevent colon adenomas. The recall has resulted in the careful review of any cardiovascular effects of other drugs in the class of drugs known as COX-2 inhibitors.
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View Archive of Director's Updates
Progress with a Purpose - A series designed to bring the nation's leaders to NIH to discuss the extraordinary advances in their fields as we work toward eliminating the suffering and death due to cancer by 2015.
02/02/04 Mark B. McClellan, M.D., Ph.D.
03/19/04 Carl B. Feldbaum
09/16/04 Julie Louise Gerberding, M.D., M.P.H.
Director's Seminar Series
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NCI Cancer Bulletin
The NCI Cancer Bulletin provides useful and authoritative news about cancer research, including important NCI programs and initiatives. With special reports and regular features, the NCI Cancer Bulletin is a valuable resource for the cancer community.
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The cancer Biomedical Informatics Grid (caBIG) Initiative - Designing and Deploying a Novel, Community-Based Cancer Research Platform
caBIG is a new initiative coordinated by NCI in partnership with other members of the cancer research community. caBIG seeks to create a network that links organizations, institutions, and individuals to enable the sharing of cancer research infrastructure, data, and tools. It is an open-access, open-source activity that promises to expedite progress in cancer research.
NIHSeniorHealth
This Web site makes aging-related health information easily accessible for people seeking reliable, easy-to-understand online health information. It was developed by the National Institute on Aging and the National Library of Medicine, with information from NCI and other components of NIH. Topics include breast, colorectal, lung, and prostate cancers.
The Nation's Investment in Cancer Research for Fiscal Year 2005
Each year, as mandated by the National Cancer Act of 1971, NCI prepares a plan for building on research successes, supporting the cancer research workforce with the technologies and resources it needs, and ensuring that research discoveries are applied to improve human health. This annual plan and budget proposal is provided directly to the President of the United States for formulating the budget request to Congress.
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The National Advanced Technologies Initiative for Cancer: Harnessing the Full Potential of Advanced Technologies to Eliminate Suffering and Death Due to Cancer
Our nation's past successes in creating technologies to enhance scientific discovery - from the space program to the Human Genome Project - have produced dramatic scientific breakthroughs and advances. Now we have an opportunity to achieve an equally unimagined goal: to eliminate suffering and death due to cancer.
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Welcome to NCI
I invite you to explore our Web site for valuable cancer-related health information and to find out more about the exciting work being conducted by NCI-supported scientists throughout the country.
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