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National Breast and Cervical Cancer Early Detection Program Breast and Cervical Cancer logo
Breast and Cervical Cancer > Awareness and Pap Test Information

Cervical Cancer Health Awareness

Cervical Cancer and Pap Test Information

According to the American Cancer Society, an estimated 10,520 new cases of invasive cervical cancer will be diagnosed in 2004 and about 3,900 women will die of the disease.1 The good news is that cervical cancer is preventable and curable if it is detected early.

The National Breast and Cervical cancer Early Detection Program icon Learn more about the National Breast and Cervical Cancer Early Detection Program.
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1Source: Cancer Facts and Figures 2004, American Cancer Society, 2004.


Why get a pap test?

Find out where you can get a free or low-cost mammogram and Pap test.

Cervical cancer rates are higher among women aged 40 years and older; however, cervical intraepithelial neoplasia (or CIN), the precursor lesion to cervical cancer, most often occurs among young women. Screening women using the Papanicolaou (Pap) test is an important strategy that can prevent cervical cancer from developing most of the time by finding lesions at an early stage when they can be removed before they become cancer.

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New Screening Interval Recommendations

A recent publication entitled "Risk of Cervical Cancer Associated with Extending the Interval between Cervical-Cancer Screenings" found evidence that most women can safely extend their cervical cancer screening interval from once a year to once every three years. The authors used data from the National Breast and Cervical Cancer Early Detection Program to estimate the risk involved in extending the screening interval for Pap tests from each year (annually) to every two years or every three years.

The researchers also estimated the average numbers of additional Pap tests and colposcopic examinations that would be needed to avert one case of cancer with the use of various screening intervals among women of various ages.

According to lead author George Sawaya, MD, of the University of California, San Francisco, for women aged 30 years or older who wait three years to have a Pap test after they have had three or more negative annual Pap tests, the increase in risk of developing cervical cancer is approximately three in 100,000. He said the study provides information for women and their clinicians in making informed decisions about how often to be screened.

Coauthor Herschel Lawson, MD, of the CDC, said, "These results validate the decision of the National Breast and Cervical Cancer Early Detection Program to lengthen the screening interval of program-enrolled women with multiple successive normal Pap tests and concentrate program resources on identifying and screening women not previously screened or not screened for three or more years."

Sawaya GF, McConnell KJ, Kulasingam SL, Lawson HW, Kerlikowske K, Melnikow J, Lee NC, Gildengorin G, Myers ER, Washington AE. Risk of Cervical Cancer Associated with Extending the Interval between Cervical-Cancer Screenings.* The New England Journal of Medicine 2003;349(16):1501–1509.

The following organizations now recommend cervical cancer screening at longer intervals (2—3 years):

*Links to non-Federal organizations found at this site are provided solely as a service to our users. These links do not constitute an endorsement of these organizations or their programs by CDC or the Federal Government, and none should be inferred. The CDC is not responsible for the content of the individual organization Web pages found at these links.


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Basic Facts and Risk Factors

New Cervical Cancer Fact Sheet
A new cervical cancer fact sheet Basic Facts on Screening and the Pap Test is now available. The fact sheet has been written at the sixth grade reading level and addresses the basics of cervical cancer and testing.

Risk Factors Associated with Cervical Cancer
While cervical cancer is rare, risk factors associated with cervical cancer include the following

  • Failure to receive regular Pap test screening
    Even though never and rarely screened women make up a small proportion of the overall population (10 to 15 percent), they have the greater burden of disease (60 percent of women newly diagnosed). Data indicate that half of women with newly diagnosed invasive cervical cancer have never had a Pap test and 10% have not been screened within the past 5 years.

  • Human papillomavirus (HPV) infection
    While HPV rarely causes cervical cancer, experts agree that infection with certain strains of the HPV is one of the strongest risk factors for cervical cancer.

  • Immunosuppressive disorders
    Women with HIV/AIDS or other immunosuppressive disorders are at greater risk of developing cervical cancer from HPV infection:

More Information on Cervical Cancer and HPV


*Links to non-Federal organizations found at this site are provided solely as a service to our users. These links do not constitute an endorsement of these organizations or their programs by CDC or the Federal Government, and none should be inferred. The CDC is not responsible for the content of the individual organization Web pages found at these links.


Please note: Some of these publications are available for download only as *.pdf files. These files require Adobe Acrobat Reader in order to be viewed. Please review the information on using and downloading Acrobat Reader software.

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Strategies for Reaching Underserved Populations

Cervical Cancer Mortality Among Foreign-Born Women Living in the United States, 1985 to 1996
According to the study, Cervical Cancer Mortality Among Foreign-Born Women Living in the United States, 1985 to 1996, deaths and death rates from cervical cancer increased for foreign-born women while continuing to decrease for U.S.-born women from 1985 through 1996. Increases in death rates among foreign-born women were highest in the South while, cervical cancer deaths and death rates for U.S.-born women decreased uniformly in all regions.

Although an estimated 12,200 cases of invasive cervical cancer were expected to be diagnosed in 2003 and an estimated 4,100 cervical cancer deaths were expected in 2003, mortality rates have declined over the past several decades largely as Pap screening has become more prevalent. Hard to reach populations are increasingly becoming the focus of efforts to encourage cervical cancer prevention and early detection.

Findings from the study indicate that cervical cancer control efforts should be intensified in areas of the United States with large foreign-born communities. Additionally, doctors and health professionals should be educated about the need for improved cervical cancer testing among foreign-born women living in the U.S.

Seeff LC, McKenna MT. Cervical Cancer Mortality Among Foreign-born Women Living in the United States, 1985 to 1996.* Cancer Detection and Prevention 2003;27(3):203-208.

Outreach Literature Review
The incidence and mortality rates for cervical cancer have leveled off during the past 40 years except for foreign born-women, where it continues to rise. With early detection through Pap test screening, cervical cancer can be mostly prevented. Minority populations and persons of low socioeconomic status, however, still have high incidence and mortality rates. The following information summarizes the main findings in the cervical cancer screening outreach literature and is organized by population or ethnic group. These summaries address some barriers to Pap tests screening and some strategies currently under study that may improve outreach to specific populations.

Asian American and Pacific Islanders


Training on Understanding Cultural and Psychosocial Barriers to Pap Testing
The American Social Health Association (ASHA), in cooperation with the American Society for Colposcopy and Cervical Pathology (ASCCP) developed the training, Understanding Cultural and Psychosocial Barriers to Pap Testing.* This course seeks to facilitate increased Pap testing and follow-up rates by addressing cultural health beliefs and barriers and how they affect Pap testing use. The following populations were identified as under-screened: underinsured and uninsured women, women of lower socioeconomic status, women from rural areas, ethnic minority women and lesbian women.

In addition to this CME opportunity, ASCCP and ASHA are offering six additional training courses*

  • The Natural History and Epidemiology of HPV
  • Follow-up After an Abnormal Pap: Addressing Barriers
  • The ASCCP Guidelines to Managing AGC
  • The ASCCP Guidelines to Managing ASC
  • Colposcopy of High Grade Lesions
  • Immune Response to HPV

Information Resources

*Links to non-Federal organizations found at this site are provided solely as a service to our users. These links do not constitute an endorsement of these organizations or their programs by CDC or the Federal Government, and none should be inferred. The CDC is not responsible for the content of the individual organization Web pages found at these links.


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Information for Clinicians

  • Reporting Pap Tests
    Bethesda 2001 updates the earlier Bethesda System, first published in 1989 and revised in 1991. The 2001 version reflects the most current knowledge about the biology of Pap test abnormalities and addresses new screening technologies that appeared in the past decade.
  • Managing Abnormal Pap Tests*
    American Society for Colposcopy and Cervical Pathology guidelines for the management of abnormal Pap tests.
  • Advances In Cervical Cancer Prevention*
    Association of Reproductive Health Professionals published clinical proceedings.

*Links to non-Federal organizations found at this site are provided solely as a service to our users. These links do not constitute an endorsement of these organizations or their programs by CDC or the Federal Government, and none should be inferred. The CDC is not responsible for the content of the individual organization Web pages found at these links.


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Page last reviewed: Tuesday, October 12, 2004

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