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Office of Genomics and Disease Prevention
   

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The Prevention Effectiveness Fellowship

National Center for Environmental Health &
Office of Genomics and Disease Prevention


The mission of NCEH is to provide national leadership, through science and service, to promote health and quality of life by preventing and controlling disease, birth defects, disability, and death resulting from interactions between people and their environment. The mission of OGDP is to promote and coordinate the integration of genetics into public health research and services throughout CDC. For example, OGDP encourages research on gene-environment interactions to gain insight into more effective disease prevention opportunities that may come from targeting the environmental factors that interact with genetic susceptibility to produce disease. OGDP also seeks to address policy questions arising from the identification of genetic risk factors for disease and the development of laboratory tests for susceptibility genotypes. OGDP is located administratively within NCEH, and works closely with programs in NCEH and other centers at CDC. The Prevention Effectiveness Fellow at OGDP/NCEH would have the opportunity to participate in one of the emerging areas of public health in the new millennium.

Potential and Ongoing Research Projects for Fellow Involvement

1. Economists and epidemiologists at CDC are engaged with academic partners to assess the costs and likely effectiveness of population-based screening for hereditary hemochromatosis. The Fellow would have the opportunity of working with experienced public health economists to update and elaborate a cost-effectiveness model for hemochromatosis screening of adults.

2. Genetic tests for mutations that increase risks for certain kinds of cancer are already available and being promoted. Evaluation of the risks and benefits of such tests from an individual perspective can be modeled with the end product being the development of an interactive decision model that providers could use to counsel individuals regarding the decision to be tested.

3. The largest genetic testing program in the United States is the screening of dried blood spots from 3.9 million newborns each year for a number of metabolic or genetic diseases. A new laboratory technology called tandem mass spectrometry has been developed that may fundamentally alter the way newborn screening is done. A quantitative and qualitative policy analysis of the implications of this technology is urgently needed. This project would be done in collaboration with the Division of Laboratory Sciences at NCEH.

For information on how to apply, visit http://www.cdc.gov/epo/fellow.htm

EPO information: EIS Officer


Last Updated August 14, 2004