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Office of Genomics and Disease Prevention  
Office of Genomics and Disease Prevention

HuGE Case Studies
Welcome to the Office of Genomics and Disease Prevention’s HuGENet™ Case Studies Series, an on-line presentation designed to sharpen your epidemiological skills and enhance your knowledge of the genetics of chronic diseases.
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Purpose

To train health professionals in the practical application of human genome epidemiology (HuGE), which translates gene discoveries to disease prevention by integrating population-based data on gene-disease relationships and interventions.  Students will acquire conceptual and practical tools for critically evaluating the growing scientific literature in specific disease areas.

Instructions

Case studies are presented as follows:

  1. Educational objectives
  2. Case studies
    • Overview about the topic followed by
    • A summary of the information contained in each article
    • Questions and answers about the article
    • Workspace and an opportunity to submit your answer
    • Our answer key
  3. Bibliography
  4. Medline Search Opportunity

*Note: Although you may quit and resume at any time, it is important to read the case study in the order in which it is presented.

Case Studies  

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NOD2 and Crohn disease
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Factor V Leiden and Venous Thrombosis
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Fictional Scenario To Test Your Knowledge of Gene-Environment Interaction: Rheumatoid Arthritis, Herbal Supplements and Fictitious Rheumatoid Arthritis Gene
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Genomics and Cancer Prevention
Last Updated October 12, 2004