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Publications |
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CDC Distributed Publications |
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International Publications |
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Targeting |
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Risk Factors |
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U.S. Trends |
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Interventions |
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Laboratory |
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Laboratory: |
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1. |
Title: Impact
of Lead-Based Paint Abatement on Children's Blood Lead Levels, St. Louis
Publication: Am J Epidemiol 1994; 139: 1016-1026. Abstract:
In order to evaluate the effectiveness
of lead-based paint (LBP) hazard abatement in reducing children's blood lead (PbB) levels,
we conducted a retrospective cohort study in St. Louis, Missouri. LBP hazard abatement
consists of the removal of peeling and chipping lead-based paint. We reviewed
environmental and medical records of the St. Louis City Health Department and abstracted
data on children with PbB levels greater than or equal mg/dL during 1989 or 1990. Among
185 children selected, 54 children had not moved or received chelation therapy and had
their PbB levels measured 10 to 14 months after diagnosis. The geometric mean (GM) PbB
level decreased 23% among children living in abated dwellings (n = 37) and 12% among
children in non-abated dwellings (n = 17) (p = 0.07, t-test). The estimated size of the
abatement effect was similar using multiple regression (-12%, p = 0.06) and generalized
linear models (-5% to -16%, p = 0.003), when adjusted for important covariates. The effect
of abatement was much greater among children whose PbB levels at diagnosis were greater
than or equal 35 mg/dL.Centers for Disease Control and Prevention. |
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2. |
Articles or
citations of studies dealing with the importance of nutrition in minimizing the effects of
lead exposure in young children:
- Hu H, Kotha S, Brennan T. The Role of
Nutrition in Mitigating Environmental Insults: Policy and Ethical Issues. Environmental
Health Perspectives. 103 (Supplement 6): 185-190 (1995).
- Mahaffey K. Nutrition and Lead:
Strategies for Public Health. Environmental Health Perspectives. 103 (Supplement 6):
191-196 (1995).
- Mahaffey K. Environmental Lead Toxicity:
Nutrition as a Component of Intervention. Environmental Health Perspectives. 89: 75-78
(1990).
- Goyer R. Nutrition and Metal Toxicity.
American Journal of Clinical Nutrition. 61 (Supplement): 646S-650S (1995).
- Sargent J. The Role of Nutrition in the
Prevention of Lead Poisoning in Children. Pediatric Annals. 23 (11): 636-642 (1994).
- Lucas S, Sexton M, Langenberg P.
Relationship Between Blood Lead and Nutritional Factors in Preschool Children: A
Cross-sectional Study. Pediatrics. 97: 74-78 (1996).
- Ruff H, Markowitz M, Bijur P, Rosen J.
Relationships among Blood Lead Levels, Iron Deficiency, and Cognitive Development in
Two-Year-Old Children. Environmental Health Perspectives. 104 (2): 180-185 (1996).
- Bruening K, Kemp F, Simone N, Holding Y,
Louria D, Bogden J. Dietary Calcium Intakes of Urban Children at Risk of Lead Poisoning.
Environmental Health Perspectives. 107 (6): 431-435 (1999).
- Simon J, Hudes E. Relationship of
Ascorbic Acid to Blood Lead Levels. JAMA. 281 (24): 2289-2293 (1999).
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