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Doxycycline and penicillin G procaine
are antibiotics used to treat bacterial infections in many different parts of
the body. They do not work for viral infections (for example, the common cold).
Doxycycline and penicillin G procaine have been approved for all forms of
anthrax. (inhalational, gastrointestinal, and cutaneous). In October 2001, FDA
published a Federal Register notice clarifying that these drugs were
approved for inhalational anthrax (post-exposure). Use of doxycycline in
children under 8 presents special concerns because of possible tooth
discoloration. Long-term use of intravenous doxycycline or penicillin G procaine
presents safety concerns, and patients should be switched, when appropriate, to other antibiotics to
complete a 60 day course of therapy for inhalational anthrax (post-exposure).
Related Links from FDA
Background Information
For more information about doxycycline and penicillin G procaine,
please contact the Division of Drug Information at druginfo@cder.fda.gov
or 1-888-INFOFDA (463-6332).
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Drug Information
FDA/Center for Drug Evaluation and Research
Last Updated: June 18, 2003
Originator: OTCOM/DLIS
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