With support from NCRR, 10 Islet Cell Resource (ICR) Centers isolate, purify,
and characterize human pancreatic islets for subsequent transplantation into patients
with type I diabetes. The ICR centers procure whole pancreata and acquire relevant data
about donors; improve islet isolation and purification techniques; distribute
islets for use in approved clinical protocols; and perfect the methods of storage
and shipping. In this way, the centers optimize the viability, function, and availability
of islets and help clinical researchers capitalize on the recently reported successes
in islet transplantation.
The NCRR Division for Clinical Research Resources (DCRR) supports the ICR centers, which will be
electronically linked through the Administrative and Bioinformatics Coordinating Center
(ABCC). The ABCC, located at the City of Hope National Medical Center in Duarte,
California, provides database and other informatics support to the ICR centers to give the
research community a single entry point to the program. Qualified clinical researchers
from not-for-profit, domestic institutions may request islets by submitting a written
application to the director of the ABCC.
Administrative and Bioinformatics Coordinating Center (ABCC):
City of Hope National Medical Center (Duarte, CA)
Division of Information Sciences
Contact: Dr. Joyce C. Niland, Director
Telephone: 626-301-8802
e-mail: jniland@coh.org
ICR Locations:
City of Hope National Medical Center and Beckman Research Institute (Duarte, CA)
Contact: Dr. Fouad Kandeel
Telephone: 626-301-8486
e-mail: fkandeel@coh.org
Columbia University, College of Physicians and Surgeons (New York, NY)
Contact: Dr. Mark Hardy
Telephone: 212-305-5502
e-mail: mah1@columbia.edu
Joslin Diabetes Center (Boston, MA)
Contact: Dr. Gordon Weir
Telephone: 617-732-2581
e-mail: gordon.weir@joslin.harvard.edu
Puget Sound Blood Center (Seattle, WA)
Contact: Dr. Jo Anna Reems
Telephone: 206-292-2317
e-mail: joanna@psbc.org
University of Colorado Health Science Center (Denver, CO)
Contact: Dr. Ronald G. Gill
Telephone: 303-315-6390
e-mail: ron.g.gill@uchsc.edu
University of Miami (Miami, FL)
Contact: Dr. Camillo Ricordi
Telephone: 305-243-6913
e-mail: ricordi@miami.edu
University of Minnesota (Minneapolis, MN)
Contact: Dr. Bernhard Hering
Telephone: 612-626-5697
e-mail: bhering@umn.edu
University of Pennsylvania (Philadelphia, PA)
Contact: Dr. Ali Naji
Telephone: 215-662-2066
e-mail: alinaji@mail.med.upenn.edu
University of Tennessee (Memphis, TN)
Contact: Dr. A. Osama Gaber
Telephone: 901-448-5924
e-mail: agaber@utmem.edu
Washington University (St. Louis, MO)
Contact: Ms. Barbara Olack
Telephone: 314-362-8319
e-mail: olackb@msnotes.wustl.edu
NIDDK Collaborative Islet Transplant Registry:
The EMMES Corporation (Rockville, MD)
Contact: Ms. Nicole Close
Telephone: 301-251-1161
e-mail: nclose@emmes.com
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