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Oregon Evidence-based Practice Center


The Oregeon Evidence-based Practice Center in Portland, Oregon, serves as a resource center for the production of systematic reviews and related projects in evidence-based medicine. The focus of the Center is in the areas of adult health, prevention, mental health and substance abuse, and dental health.


EPC Director Mark Helfand, M.D., M.S., M.P.H., also oversees the Oregon EPC Outcomes Research Unit, which provides research and consulting services in database design, data management, clinical guidelines, performance measurement, cost effectiveness analysis, and design and management of research and clinical quality improvement projects. Associate Director Merwyn Greenlick, Ph.D., is professor and chair of the Department of Public Health and Preventive Medicine and was the former director of the Kaiser Permanente Center for Health Research. EPC Associate Director William Hersh, M.D., chair of the Division of Medical Informatics and Outcomes Research, is one of several Oregon EPC faculty involved with the Cochrane Collaboration. Heading the work at the Center for Health Research is Jack F. Hollis, Ph.D., a senior investigator who directs CHR's program in epidemiology and disease prevention, including studies in health behavior and health promotion.

Investigators with the Evidence-based Practice Center have a particular interest in diagnostic technology assessment, prevention effectiveness, evidence-based informatics, research in managed care, and critical appraisal of cost-effectiveness analysis and decision analysis. In the past, faculty affiliated with the Center have investigated areas such as acute head injury, thyroid function tests, smoking cessation programs, cancer screening, diagnostic use of upper GI endoscopy, asthma diagnosis and management, anterior cruciate ligament surgery, and statewide trauma systems.


The Center is a collaboration between Oregon Health & Science University and the Kaiser Permanente Center for Health Research, which has strong expertise in the areas of prevention effectiveness, health economics, and managed care. Since 1964, the CHR has conducted public domain research on a broad range of health and medical care issues, using Kaiser Permanente's large operating medical and dental care system as a research setting and laboratory. Other scientific partners include the Portland Veterans Affairs Medical Center and the Center for Outcomes Research and Education, part of the Providence Health System in Portland. This collaboration enjoys support from, and seeks to serve, private organizations and governmental agencies engaged in the delivery of care services throughout the Northwest.

Additional Information

All inquiries related to the Oregon Evidence-based Practice Center should be directed to E-mail address: epc@oshu.edu. The Center's Web site is http://www.ohsu.edu/epc.

Or contact:

Mark Helfand, M.D., M.S., M.P.H.
Oregeon Evidence-based Practice Center Director
Assistant Professor, School of Medicine
Division of Medical Informatics and Outcomes Research
3181 SW Sam Jackson Park Road
Portland, OR 97201-3098
Phone: (503) 494-4277
Fax: (503) 494-4551
E-mail: helfand@ohsu.edu

Internet Citation:

Oregon Evidence-based Practice Center. Profile, May 2004. Agency for Health Care Policy and Research, Rockville, MD. http://www.ahrq.gov/clinic/epc/ohsuepc.htm

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